Hi Nazanin

the nonlinear registration is actually to our segmentation atlas (*.gca). I guess you could try using something else, but you should extract a mean intensity image from the gca as a target, not the MNI305. You can do this with:

mri_convert -nth 0 <file>.gca mean_gca.mgz

FYI, this:

mri_convert -nth 1 <file>.gca labels_gca.mgz

would give you the highest prior label at each spot (and 2 would give you the prior)

cheers
Bruce



On Mon, 30 Oct 2017, N Saf wrote:

Dear Experts,
In the volume-based stream, if I'm right the FreeSurfer does two registration 
with MNI305 ,one affine and one
nonlinear , is it possible to perform the nonlinear registration somewhere else 
and then use the result in
FreeSurfer and run the rest of the analysis ? 

thank's alot for your great support.

BRG,
Nazanin


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