It might capture specific anatomical features that are unique to your 
data set. It can be tricky though as you need to make sure to include an 
equal mix of all your groups. Eg, if you have 20 ADs and 10 controls, 
you'd need to make an atlas with 10 ADs and 10 controls.


On 11/08/2017 03:57 PM, Mehta, Chintan wrote:
> Dear Doug,
> Are there reasons why registering to my_subject_average 
> (template defined from, say, average in a cross-sectional sample) can 
> be better than registering to fsaverage?
> Thank you.
> Best,
> Chintan
>
>
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