Thanks for the explanation, Bruce!

Best Regards,
Yi

On 13 Nov 2017, at 5:48 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu> wrote:

Hi Yi

yes, brainmask.mgz is the skull stripped image.

And no, n3 is pretty gentle so I would think letting our normal intensity 
normalization run would be fine (and better than not doing it)

cheers
Bruce


> On Mon, 13 Nov 2017, Yi Li wrote:
> 
> Hi Bruce,
> 
> Thanks for the help! Is the skull-stripped image in Brainmask.mgz?
> 
> Another question: since my raw image has gone through B1 correction and N3 
> normalization, will you suggest I omit the nu and normalize step in 
> -autorecon1?
> 
> Best Regards,
> Yi
> 
> 
> -----Original Message-----
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl
> Sent: Monday, November 13, 2017 10:50 AM
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] [strip skull for unregistered images]
> 
> Hi Yi
> 
> autorecon1 should do the skull stripping, so there is no need for the 
> separate mri_mask call. The threshold of '5' is so to preserve edits in which 
> voxels are turned 'off' (they are set to 1 I believe, but we reserve
> 2-4 as additional 'off' values).
> 
> The masking will not transform the voxel coordinates of the image
> 
> cheers
> Bruce
> 
> 
>> On Mon, 13 Nov 2017, Yi Li wrote:
>> 
>> 
>> Dear FS experts,
>> 
>>  
>> 
>> I would like to strip skulls from unregistered images which have gone
>> through GradWarp, B1-correction, N3 normalization and phantom-based scaling.
>> I run the following two commands in freeSurfer:
>> 
>> recon-all -autorecon1 -subjid <subjid>
>> 
>> mri_mask -T 5 T1.mgz brainmask.mgz T1.final.mgz
>> 
>>  
>> 
>> My questions are
>> 
>> 1)      Currently I use 5 as threshold (-T 5). Is there a guidance for
>> the setting of this parameter?
>> 
>> 2)      In the output file T1.final.mgz, is the skull-stripped image
>> represented in ijk space (image index space) or in XYZ space (via
>> transformation matrix)?
>> 
>> 3)      If the skull-stripped image is represented in XYZ space, how
>> do I get it in ijk space?
>> 
>>  
>> 
>> Thanks in advance for the help!
>> 
>>  
>> 
>> Best Regards,
>> 
>> Yi Li (PhD)
>> 
>> Senior Computational Scientist
>> 
>> Computational Sciences
>> 
>> The Jackson Laboratory
>> 
>> Farmington, CT 06032
>> 
>> Tel: 860-837-2156
>> 
>>  
>> 
>> ---
>> 
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