If you want to test for an interaction between Age and Weight, you need 
to create a new covariate which is Age*Weight, then test the sig of this 
covariate. I would demean Age and Weight for both the inidvidual 
covaraite and before computing the product.


On 04/12/2018 12:35 PM, David S Lee wrote:
> Hi FreeSurfer Experts,
>
> I have two groups (Male and Female) and two covariates (Age and 
> Weight). I want to test change of cortical thickness with age and 
> weight, after removing effects of Group. In other words, is there an 
> interaction between age and weight, regressing out the effects of groups.
>
> How can I set up my Design Matrix to test this?
>
> Thank you,
>
> -- 
> David S. Lee
> Associate Research Specialist
> Center for Healthy Minds
> University of Wisconsin - Madison
> (608) 890-1115 <tel:%28608%29%20890-1115>
>
>
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