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Hi Doug,

we have v.6.0 on a cluster, so I quickly run one subject there (the one,
whose files and pictures I attached previously). This time the BBR-sum was
0.9476, so slightly better but still bad :(

Best regards,
Patrycja

2018-05-14 16:56 GMT+02:00 Douglas Greve <dgr...@mgh.harvard.edu>:

> It might be the initialization with FLIRT. Do you have access to FS6.0? If
> so, can you try running 6.0 instead to see if it fixes the problem?
>
> On 5/14/18 4:05 AM, Patrycja Naumczyk wrote:
>
>
> Hi All,
>
> I'm still struggling with the registration - so far I tried performing
> slice-timing and/or motion correction in SPM instead of FS, but that did
> not changed the results.
>
> I came up with a new idea, but don't know how to verify it. I used GE
> scanner for data acquisition, which meant I had to convert the fMRI data
> and make the directory tree myself (as the dcm-unpack did not work well). I
> used MRIconvert for converting to nifti, which does not preserve some of
> the FS-Fast crucial data (i.e. the TR, which I had to update with
> mri_convert in all files). Is it possible that this is the reason of
> bbregister's misalignment? Like, the script needs some additional
> information that should be embedded in the data and is not (due to outside
> conversion)?
>
> I was thinking of maybe working around the problem by manually registering
> the rs-fMRI template to task-based template and then merging the two
> registration files (rs-fMRI_to_taskBased and taskBased_to_anatomical) and
> feeding that to the preproc-sess with "-regfile" flag. Potentially it could
> work, but maybe there is a simpler solution?
>
> The only difference between the properly aligned task-based fMRI and
> faulty rs-fMRI is that the latter has lower resolution (task based:
> 2.5x2.5x3.2mm, rs-fMRI: 3.4x3.4x3.3mm) and was longer (task-based: 160
> volumes, rs-fMRI: 400 volumes).
> I attach screenshot of the problem in tkregister. Left - task-based fMRI,
> middle - rs-fMRI, right - rs-fMRI with task-based registration file used.
>
> Best regards,
> Patrycja
>
> 2018-05-12 15:20 GMT+02:00 Patrycja Naumczyk <patrycja.naumc...@gmail.com>
> :
>
>> Hi All,
>>
>> I'm running FS v. 5.3 on Gentoo Linux.
>>
>> I made a study, where all subjects during one session had T1,
>> resting-state and task-based fMRI. I processed all anatomical data through
>> standard recon-all (it worked well), and the task-based fMRI through
>> FS-FAST - which also generated fine results.
>>
>> Now I wanted to look into the rs-fMRI with functional connectivity. I
>> made a separate directory tree for this purpose (in order not to mess task
>> and rest data), and unfortunately the bbregister doesn't handle the
>> registration during preproc-sess properly. Misalignment is big and covers
>> all runs. BBR-sums of all of participants (N=39) exceed 0.8 (some of them
>> exceed 1.0). What's interesting is that bbregister previously managed the
>> task-based fMRI data well (with no BBR-sum exceeding 0.8). I double checked
>> the data for any i.e. conversion/orientation faults, but found none.
>>
>> The command for preprocessing was identical in rs-fMRI and task-based
>> fMRI:
>> preproc-sess -sf <sessid> -d <ProjectDirectory> -surface fsaverage lhrh
>> -mni305 -fwhm 5 -per-run -fsd bold
>>
>> I attach exemplary register log file from rs-fMRI subject registration
>> (BBRsum=0.9704). This subject's task-based fMRI BBR-sum was 0.55.
>>
>> My question is - what may be the cause of such a discrepancy between
>> registration of two functional runs taken one by one (the rs-fMRI preceded
>> the task based)? Does anyone have an idea how to fix the problem?
>>
>> Best regards,
>> Patrycja
>>
>
>
>
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