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Dear Freesurfer experts,

Could you please let me know how to normalize fMRI data without upsampling
the original voxel size from 5 x 5 x 7 mm to 2 x 2 x 2 mm? I have tried
this as follows:

1. Register functional (data.nii) to anatomical matrix



    bbregister --s $subject --bold --init-fsl --mov data.nii --reg
register.dof6.dat



2. Register anatomical to mni152:

      mni152reg --s $subject



3. Create registration between functional and mni152

      mri_matrix_multiply -im register.dof6.dat -iim reg.mni152.2mm.dat -om
reg.mni152.dat



4. Resample func to mni152 space

     mri_vol2vol --targ $FSLDIR/data/standard/MNI152_T1_2mm.nii.gz --mov
data.nii --reg reg.mni152.dat --o data.mni152.nii --no-resample



I checked the registrations after each step. After step 4, the functional
data and the template are not fully aligned if I use “no-resample”.
Without no-resample, the registration seems successful, but the fMRI data
has a voxel size of 2mm.

Best,

Maria
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