Have you looked at this page? https://surfer.nmr.mgh.harvard.edu/fswiki/FsgdExamples You should be able to generalize the two groups, one covariate, to three groups
On 08/24/2018 01:06 PM, O'Dell, Ryan wrote: > > External Email - Use Caution > > Dear freesurfers, > > > I have what is likely a basic question but I'm new not only to > FreeSurfer but contrast matrix design and group analysis as well, and > was hoping for some help/clarification. > > > Basically I want to run a GLM on our structural/functional data in > order to determine if there's any significant correlation between > cortical thickness and cortical amyloid deposition (measured by PiB), > factoring in any potential effects of APOE genotype (e3e3, e3e4, > e4e4). This means I want to construct an FSGD file with a 3 groups > (the 3 APOE genotypes) and 1 covariate (our calculated cortical > composite PiB value) for this analysis. However, I'm struggling with > the proper contrast designs which test the various hypotheses in such > a setup. > > > Any answers, thoughts, or insights would be greatly appreciated. I > know this type of analysis is also likely QDEC-able, but I think the > FSGD approach would be more beneficial for my understanding of > contrast matrix design. Please let me know if I've left out any > information that could potentially help clarify my question/request. > > > Best, > > > Ryan O'Dell MD/PhD > > PGY2 Psychiatry Resident, NRTP > > Yale University > > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
