Don't use gender as a continuous variable. You need four classes
(TLE-Male, TLE-Female, etc) and change the contrast to reflect it,
otherwise I think it looks ok. Load the sig.mgh file into freeview (or
the tksurferfv freeview wrapper)
On 2/19/2020 10:31 PM, 邓刊 wrote:
External Email - Use Caution
Dear Freesurfer support,
we met some probelm when we investigate difference between two groups.
We have two sets of data, one is the TLE group, the other is the
extraTLE. We also has the variables: age,gender and neuropsychological
test scores. We want to analyze the relationship between cortical
thickness and neuropsychological test, controlling for age, gender and
group.
The contrast in the full DODS model in the mri_glmfit is 0 0 0 0 0.5
0.5 0 0, with the fsgd file being:
GroupDescriptorFile 1 Title MyTitle MeasurementName thickness Class
Class1_TLE Class Class3_extra_TLE Variables Age factor4 gender Input
PT1_01 Class1_TLE 23 12 1 Input PT1_03 Class1_TLE 38 10.26 0 Input
PT1_04 Class1_TLE 26 13 0 Input PT1_06 Class1_TLE 45 13 1 Input PT1_11
Class1_TLE 20 15 1 Input PT1_12 Class1_TLE 23 10.26 0 Input PT1_14
Class1_TLE 39 9 1 Input PT1_27 Class1_TLE 51 14 1 Input PT1_32
Class1_TLE 33 11 0 Input PT1_33 Class1_TLE 27 8 1 Input PT1_34
Class1_TLE 19 8 0
Preproc was done with:
mris_preproc --fsgd patients_age_gender_Arithmetic.fsgd \ --cache-in
thickness.fwhm15.fsaverage \ --target fsaverage \ --hemi rh \ --out
rh_thickness_Arithmetic/rh.thickness.fwhm15_arithmetic.mgh
GLM was done with:
mri_glmfit --y
rh_thickness_Arithmetic/rh.thickness.fwhm15_arithmetic.mgh \
--fsgd patients_age_gender_Arithmetic.fsgd dods \ --C
difference_Arithmetic_all.mtx \ --surf fsaverage rh \ --glmdir
rh_thickness_Arithmetic
My questions are：
(1)Are the command lines, fsgd file and the contrast matrix correct?
(2)We have used qdec (DODS) to visualize the results, but I can't open
the sig.mgh file. I dont know why? The terminal shows that :
Reading /usr/local/freesurfer/tktools/tkUtils.tcl Using
/usr/local/freesurfer/lib/tcl/fsgdfPlot.tcl ERROR: MRISread: file
'/usr/local/freesurfer/subjects/Neuropsychology/rh_thickness_Arithmetic/difference_Arithmetic_all/F.mgh'
has 0 vertices! Probably trying to use a scalar data file as a
surface! Invalid argument
I dont know how to solve it.I very appreciate your help.
Kind regards, Kan
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