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Dear Mr. Greve


Thanks for your suggestions.


However I'm still a bit puzzled about how to contrast two runs corresponding to 
different stimulations (StimA: runA and StimB:runB) from one subject.

I have two runs each containing a paradigm file corresponding to one of the two 
stimulations.

How is it possible to contrast those two stimulation conditions acquired in two 
different runs since one run and thus also the paradigm file does not contain 
both stimulation conditions?

Seemingly both stimulation conditions must be in one paradigm file set to 
different onset timings to perform mkcontrast-sess


My folder Structure is as follows

Project Name

Session = Subject

Runs (001, 002) = Stimulation A and Stimulation B, each with a separate 
paradigm file


I know that I do not have to model the no-stimulation periods explicitely


Best wishes

Chris

________________________________
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> im Auftrag von Douglas N. Greve 
<dgr...@mgh.harvard.edu>
Gesendet: Freitag, 6. März 2020 17:54:16
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] within-subject contrast between runs



On 3/6/2020 11:15 AM, Milde, Christopher wrote:

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Dear Freesurfer Experts,


I have a very basic questions about creating subject-wise contrasts between runs



Background

Study with two runs per subject where each run corresponds two a different 
condition (i.e. Stimulation A (on - off) and Stimulation B (on - off).

I performed the preprocessing and 1st levels stats in the native subjects space


Questions

  *   How can I obtain a within-subjects contrast between two runs (the 
Stimulation A vs. Stimulation B )  obtained in two runs within one session?

The easiest way is to code the conditions differently in the paradigm file (eg, 
instead of two conditions, you'd have 4, ARun1, BRun1, ARun2, BRun2), then just 
create contrasts as normal

  *   Can I obtain this within-subject contrast by staying in the native 
subject space?

It can be done in fsaverage or the native subject surface space, it is not 
related.

  *   Do I have to concatenate both runs and create a new parradigm file?

No, see above


Thanks for your support


Sincerely

Chris





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