If you run this, it will create a new brain.finalsurfs and rerun just what you need to rerun recon-all -s subject -autorecon2 -nogcareg -nocalabel -nonormalization2 -autorecon3

On 6/22/2020 1:20 PM, Danielian, Laura (NIH/NINDS) [E] wrote:

        External Email - Use Caution

Interesting – I never did any editing directly on the original brain.finalsurfs.mgz.  I only did cerebellar edits on the brain.finalsurfs.manedit.mgz copy of brain.finalsurfs.mgz. Looks like those edits copied over somehow.

Regardless, it sounds like this will be easy to correct.  Where can I find an unedited copy of brain.finalsurfs.mgz and when/how would I reintegrate that into the processing stream?

Thanks,

Laura

*From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Monday, June 22, 2020 at 12:13 PM
*To: *"freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] Longitudinal Stream Problem


It looks like someone edited the brain.finalsurfs.mgz. In the attached is the image of the brain.final... You can see where the brain is missing. The white surface (green line) stops at that edge. When I used the unedited brain, the surfaces went to the right place (yellow surface)

On 6/22/2020 9:21 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

    *        External Email - Use Caution *

    Thanks Douglas.  I could send other problem data sets too if it
    would help.  Just let me know.

    Thanks,

    Laura

    *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
    <mailto:dgr...@mgh.harvard.edu>
    *Reply-To: *Freesurfer support list
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Date: *Friday, June 19, 2020 at 6:10 PM
    *To: *"freesurfer@nmr.mgh.harvard.edu"
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

    OK, I have it now and am able to verify the problem. It's really
    strange -- I don't know why it is behaving like this. It may take
    me a few days to dig into.

    On 6/18/2020 11:39 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

        *        External Email - Use Caution *

        Sorry I’m not sure why it didn’t upload.  I just tried it
        again.  danielianall.tar.gz  - Should include all parts.  EM2
        is the cross-sectional.  EM is the base. EM2.long.EM is the
        long.  I also tried sending just the base again. 
        danielianbase.tar.gz.

        Thanks,

        Laura

        *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
        <mailto:dgr...@mgh.harvard.edu>
        *Reply-To: *Freesurfer support list
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Date: *Thursday, June 18, 2020 at 9:12 AM
        *To: *"freesurfer@nmr.mgh.harvard.edu"
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

        I have not seen that file appear. Can you re-upload it?

        On 6/16/2020 10:19 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

            *        External Email - Use Caution *

            Hi Douglas,

            OK I just uploaded the base separately. 
            danielianbase.tar.gz  I thought it was part of the
            original bundle.  Sorry!

            Laura

            *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
            <mailto:dgr...@mgh.harvard.edu>
            *Reply-To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Date: *Tuesday, June 16, 2020 at 10:10 AM
            *To: *"freesurfer@nmr.mgh.harvard.edu"
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

            I have your data, but it does not have the base image. Can
            you upload that as well?

            On 6/15/2020 5:15 PM, Danielian, Laura (NIH/NINDS) [E] wrote:

                *        External Email - Use Caution *

                Hi Douglas,

                I just upload the files as danielian.tar.gz.  I didn’t
                notice any damage or artifact on this particular brain
                or the others that had this same problem. This subject
                is a healthy control and most of the subjects (3 of 4)
                that are having this problem are healthy.  For each we
                used 2 T1s for the original cross-sectional input. 
                The cross was reconstructed fine as was the base and
                the 2 other longitudinal timepoints for this same
                subject.  The same is the case with the others I’m
                having trouble with – all of the their other
                timepoints are fine for the cross/base/longitudinal
                surfaces.  The warped surfaces are always lower
                posterior (cerebellum adjacent) and sometimes also
                temporal.  Upper cortical and frontal regions are
                unaffected.

                Thanks for your help!

                Laura

                *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
                <mailto:dgr...@mgh.harvard.edu>
                *Reply-To: *Freesurfer support list
                <freesurfer@nmr.mgh.harvard.edu>
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                *Date: *Friday, June 12, 2020 at 10:35 AM
                *To: *"freesurfer@nmr.mgh.harvard.edu"
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                <freesurfer@nmr.mgh.harvard.edu>
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

                Hard to tell from just that view. Was there a lot of
                brain change with that time point? Or was there an MRI
                artifact? If no to both, then you can upload all the
                cross, the base, and that one long. Follow
                instructions below (you can make one tarball for all
                subjects)

                From the linux command line,
                Create the file you want to upload, eg,
                cd $SUBJECTS_DIR
                tar cvfz subjects.tar.gz ./subject1 ./subject2
                Now log  into our anonymous FTP site:
                ftp surfer.nmr.mgh.harvard.edu
                It will ask you for a user name: use "anonymous" (no
                quotes)
                It will ask you for a password: use "anonymous" (no
                quotes)
                cd transfer/incoming
                binary
                put subjects.tar.gz
                Send an email that the file has been and the name of
                the file.








                On 6/9/2020 6:32 PM, Danielian, Laura (NIH/NINDS) [E]
                wrote:

                    *        External Email - Use Caution *

                    Hi, I’ve finished processing a data set that
                    included longitudinal data and I’m having a
                    problem with a small percentage of the
                    longitudinal timepoints. To review what I’ve done,
                    I edited all of the individual (cross-sectional)
                    timepoints until the wm and pial surfaces were
                    correct, then created the base and edited that
                    until it looked good, and then created the
                    longitudinal files for each cross-sectional
                    timepoint.  Most of these did not need editing and
                    some needed slight edits to either wm or brainmask
                    which corrected the longitudinal surfaces.

                    However, in a small handful of cases, the wm/pial
                    surfaces were so distorted that editing would not
                    fix the problem.  In these cases, longitudinal
                    surfaces were very different from both the
                    original cross-section and base.  I’ve tried to
                    attach a file that shows an example – it might
                    only affect a small portion of the brain but in
                    these cases I don’t think I could edit it to
                    improve the surfaces.  In the example I attached,
                    red/blue are from the long file and pink/lt blue
                    are from the base.

                    Do you have any suggestions for why this might be
                    happening and how to fix it?  I’m running v6.0.

                    Thanks!

                    Laura Danielian







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