What do you mean by one analysis? I don't think it would make sense to average 
the images together. If you mean that different subjects have different scans, 
then it is not ideal, but you could include scan as part of your statistical 
design. Just make sure that different populations are balanced across the 
different scans.

On 11/15/2020 9:47 PM, 王颖喆 wrote:

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Hello Freesurfer Developers,

I'm attempting to analyze data using freesurfer. The dataset we used includes 
two different series of MRI DICOM:
The first series (n=562) was collected using the following paremeters: t1_fl3d 
(Voxel Size = 0.9×0.9×1.5mm,  FOV = 220 mm, TR = 21ms, TE = 7.65ms, Flip Angle 
= 30⁰);
The second series  (n=300) : MPRAGE(Voxel Size = 1×1×1mm, FOV = 256mm, TR = 
2300ms, TE = 2.98ms, Flip Angle = 9⁰).
All brain MRIs were performed on the same 3.0T Siemens scanner.
I'd like to know if it is accpetable to include both of these imagings in one 
analysis? Is there any pre-processing step need to be done?
Thank you!

Yingzhe Wang








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