Yea, I've tried that before. It does not work very well. You can proceed, but it will not be providing you with a very good correction.

On 8/9/2021 9:30 AM, Shane Schofield wrote:

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Hi Freesurfer Experts,

I am trying to obtain coregister diffusion data b0 with T1.

One problem is that I do not have any means to correct for EPI distortions.

Because of this,  I am experimenting with DOF = 9 and DOF = 12. The mincost for 12 was consistently the lowest compared to 6 and 9 across my datasets [DOF 6 = 0.23, DOF 9 = 0.22, DOF 12 = 0.19]. However, it is hard to tell that DOF 12 is the best just by looking at the coregistered B0s overlaid on the brainmask.

Would it be fine to proceed with the DOF 12 option?

Thank you.

Best Wishes,
Shane

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