Did you read the error message? It says:
Variable 2 has character string Female
Variables should be continuous numbers
You have listed Gender and Race as strings, they have to be numbers (eg, 1, 2)
You probably want to have these be discrete variables instead of continuous

On 11/10/2021 6:20 PM, Zeng, Qi wrote:

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Hi Douglas,

Here is the command line:
mri_glmfit \
  --y rh.thickness-rate.MyStudy.10.mgh \
  --fsgd FSGD/MyStudy.fsgd dods\
  --C Contrasts/Case-Control_age_gender_race_etiv.mtx\
  --surf fsaverage rh \
  --cortex \
  --glmdir rh.thickness-rate.MyStudy.10.mgh_age_gender_race_etiv.glmdir \
  --eres-save

Also error message in terminal:
gdfRead(): reading FSGD/MyStudy.fsgd
WARNING: variable 1 is "Gender" which is often a discrete factor
  The proper way to handle discrete factors is to create classes.
  See *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://surfer.nmr.mgh.harvard.edu/fswiki/FsgdExamples <https://secure-web.cisco.com/1NHVxBIRnha6EjEdEho81-VE9d-vjJ6ivzt10z28vhX9c94pCwosQpkLG4Hfu3nLYp7KMDne5wAk9mK45YIQJEZBe6UlteF2wwLohmZJzp070UjHvv6fqugRAkgBk0uNO3Fsgo5BzblW95J5iO5sXWwZLK-LGAZJJTBaU7mLTkO5L70JRSscCW3pdc-G5KchZMbVyeY65gGH4w5MMIYBSVHvX03spMjZ85XkHbkgYYmWXTFnzqUGhqGgHygP5sLeR7OWPKIzEb7X3pHi7POf0UyEHJAZpQLU9bgT2BnOcClt0kW4mll1ODQDC2Y0U7-0f/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsgdExamples>
ERROR: gdfReadV1: Format Error: Input line 1, subjid = sub001_base
 Variable 2 has character string Female
 Variables should be continuous numbers
FSGDF Format Error: file = FSGD/MyStudy.fsgd, tag=Input

Also attached FSGD file below.
Thank you so much for the help!

Best,
Zeng




On Wed, Nov 10, 2021 at 5:41 PM Douglas N. Greve <dgr...@mgh.harvard.edu> wrote:

    please send your command line and full terminal output as well as
    the fsgd file

    On 11/10/2021 5:12 PM, Zeng, Qi wrote:

            External Email - Use Caution

    Hi Freesurfer experts,

    Here, I want to design a simple group comparison (two levels:
    Case vs. Control) and also count for 4 covariates (two continuous
    and two categoricals). However, the GLM model cannot recognize my
    discrete variables. What do you suggest to change?
    >> FSDG file:
    GroupDescriptorFile 1
    Title MyStudy
    Class Control
    Class Case
    Variables agegenderrace eTIV
    Inputsub001_baseControl85FemaleWhite1350519
    Contrast:
    >> Design matrix for Case-Control and regress out the effect of
    age, gender, race, and eTIV.
    -1 1 0 0 0 0 0 0 0 0

    Best,
    Zeng




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