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Hi Donatas,

I've read your full paper and it is very interesting. During my investigation on the use of SAMSEG and ASEG for AD/MCI patients, I've found some unexpected behaviors. I'm using the 7.2 version of Freesurfer and I've realized that I get different results using the same data but when I run the SAMSEG multiple times (on the same patient). This doesn't happen with ASEG.


Differently from using ASEG, SAMSEG provides also the chance to execute the code using multiple threads.

In the first run I've executed SAMSEG on ADNI patient id 002_S_0685 using the MP-RAGE series having ID I18211 (the link below provides the NIFTI version of the series which has been used for the processing). This patient is part of ADNI dataset.

https://secure-web.cisco.com/17-NqRPTAKNaVCf_i6zhkdra4uObi5n9QwHlBaAsfxUilF3YlRCCMnG3JWzp7vK6jLC93IssuFIawxv6AiuG07kkilM8R6uINFjkrDH88uafjcSNKfZaf_hh3l_JWeYzYT9UKCPn3mtP3yzw4fWfPczuXqpfclCm4vKIRu6oJlFJwsNo_YAP_QoAagY3LZU4UoxJnSOkZs5tP-eRBVqkzLf8Kn7_GD0OE2tUggJ9bOM6yjRATNqC6aA9Ndb_9z7uzxZOMAFfPZC2WaXdAT_aZA4bubzLI5D1JFQagC9J2VCxatC0tfvTleHPMUxuaxvon4MdteS5Mp2YWlz7RmWP7Mg/https%3A%2F%2Fdrive.google.com%2Fdrive%2Ffolders%2F15oghna17Qz-OSuo9E3-rldOt935AEEuO%3Fusp%3Dsharing <https://secure-web.cisco.com/17-NqRPTAKNaVCf_i6zhkdra4uObi5n9QwHlBaAsfxUilF3YlRCCMnG3JWzp7vK6jLC93IssuFIawxv6AiuG07kkilM8R6uINFjkrDH88uafjcSNKfZaf_hh3l_JWeYzYT9UKCPn3mtP3yzw4fWfPczuXqpfclCm4vKIRu6oJlFJwsNo_YAP_QoAagY3LZU4UoxJnSOkZs5tP-eRBVqkzLf8Kn7_GD0OE2tUggJ9bOM6yjRATNqC6aA9Ndb_9z7uzxZOMAFfPZC2WaXdAT_aZA4bubzLI5D1JFQagC9J2VCxatC0tfvTleHPMUxuaxvon4MdteS5Mp2YWlz7RmWP7Mg/https%3A%2F%2Fdrive.google.com%2Fdrive%2Ffolders%2F15oghna17Qz-OSuo9E3-rldOt935AEEuO%3Fusp%3Dsharing>

The first execution of SAMSEG was with default settings (1 thread) and results are attached, the second was using --threads 6.

These results from the SAME series are similar but they are NOT the same.

Do you have an explanation for that?

Regards
# Measure Unknown, 938678.804563, mm^3
# Measure Skull, 70514.097706, mm^3
# Measure Soft_Nonbrain_Tissue, 1117216.914116, mm^3
# Measure Brain-Stem, 19382.400237, mm^3
# Measure CSF, 510336.929212, mm^3
# Measure Left-Cerebellum-Cortex, 46227.404805, mm^3
# Measure Right-Cerebellum-Cortex, 46954.827348, mm^3
# Measure 4th-Ventricle, 1927.249860, mm^3
# Measure Fluid_Inside_Eyes, 10681.567722, mm^3
# Measure Left-Cerebral-Cortex, 194854.703127, mm^3
# Measure Right-Cerebral-Cortex, 198395.911108, mm^3
# Measure Left-Cerebellum-White-Matter, 13367.296942, mm^3
# Measure Right-Cerebellum-White-Matter, 13442.628195, mm^3
# Measure Right-Cerebral-White-Matter, 200768.332902, mm^3
# Measure Left-Cerebral-White-Matter, 199392.351036, mm^3
# Measure Right-choroid-plexus, 2202.554448, mm^3
# Measure Right-Amygdala, 1483.776188, mm^3
# Measure Left-Amygdala, 1543.083787, mm^3
# Measure Right-Hippocampus, 3889.943347, mm^3
# Measure Right-Inf-Lat-Vent, 773.181432, mm^3
# Measure Left-Hippocampus, 3957.909089, mm^3
# Measure Left-choroid-plexus, 1732.272325, mm^3
# Measure Left-Inf-Lat-Vent, 374.679073, mm^3
# Measure Optic-Chiasm, 194.020527, mm^3
# Measure Right-VentralDC, 3517.897243, mm^3
# Measure Left-VentralDC, 3616.708619, mm^3
# Measure 3rd-Ventricle, 2767.856042, mm^3
# Measure Left-Accumbens-area, 582.221221, mm^3
# Measure Left-Putamen, 4786.334982, mm^3
# Measure Right-Putamen, 4722.605242, mm^3
# Measure Right-vessel, 80.863621, mm^3
# Measure Right-Accumbens-area, 461.768868, mm^3
# Measure WM-hypointensities, 20335.889722, mm^3
# Measure Left-Lateral-Ventricle, 20190.963456, mm^3
# Measure Left-vessel, 61.352892, mm^3
# Measure Right-Lateral-Ventricle, 18727.913621, mm^3
# Measure Right-Pallidum, 1703.159618, mm^3
# Measure Left-Caudate, 3777.300280, mm^3
# Measure Right-Thalamus, 5636.150208, mm^3
# Measure Left-Pallidum, 1656.295530, mm^3
# Measure Right-Caudate, 3583.231471, mm^3
# Measure Left-Thalamus, 6017.696659, mm^3
# Measure non-WM-hypointensities, 89.673417, mm^3
# Measure 5th-Ventricle, 15.867564, mm^3
# Measure Unknown, 939056.015091, mm^3
# Measure Skull, 71767.719764, mm^3
# Measure Soft_Nonbrain_Tissue, 1112717.212711, mm^3
# Measure Brain-Stem, 19396.749933, mm^3
# Measure CSF, 511873.576213, mm^3
# Measure Left-Cerebellum-Cortex, 46226.557363, mm^3
# Measure Right-Cerebellum-Cortex, 46977.164462, mm^3
# Measure 4th-Ventricle, 1932.334854, mm^3
# Measure Fluid_Inside_Eyes, 10678.846479, mm^3
# Measure Left-Cerebral-Cortex, 195097.957627, mm^3
# Measure Right-Cerebral-Cortex, 198722.232809, mm^3
# Measure Left-Cerebellum-White-Matter, 13367.963053, mm^3
# Measure Right-Cerebellum-White-Matter, 13448.109331, mm^3
# Measure Right-Cerebral-White-Matter, 201145.753968, mm^3
# Measure Left-Cerebral-White-Matter, 199725.946038, mm^3
# Measure Right-choroid-plexus, 2196.836003, mm^3
# Measure Right-Amygdala, 1483.180736, mm^3
# Measure Left-Amygdala, 1541.752663, mm^3
# Measure Right-Hippocampus, 3885.522213, mm^3
# Measure Right-Inf-Lat-Vent, 774.735928, mm^3
# Measure Left-Hippocampus, 3954.921244, mm^3
# Measure Left-choroid-plexus, 1727.665580, mm^3
# Measure Left-Inf-Lat-Vent, 375.969644, mm^3
# Measure Optic-Chiasm, 194.100725, mm^3
# Measure Right-VentralDC, 3514.663768, mm^3
# Measure Left-VentralDC, 3624.351918, mm^3
# Measure 3rd-Ventricle, 2772.144481, mm^3
# Measure Left-Accumbens-area, 583.409147, mm^3
# Measure Left-Putamen, 4795.974528, mm^3
# Measure Right-Putamen, 4727.161970, mm^3
# Measure Right-vessel, 81.049494, mm^3
# Measure Right-Accumbens-area, 460.463919, mm^3
# Measure WM-hypointensities, 20286.439923, mm^3
# Measure Left-Lateral-Ventricle, 20198.148413, mm^3
# Measure Left-vessel, 61.483040, mm^3
# Measure Right-Lateral-Ventricle, 18752.376148, mm^3
# Measure Right-Pallidum, 1706.206364, mm^3
# Measure Left-Caudate, 3781.345908, mm^3
# Measure Right-Thalamus, 5643.708765, mm^3
# Measure Left-Pallidum, 1657.771589, mm^3
# Measure Right-Caudate, 3579.185246, mm^3
# Measure Left-Thalamus, 6021.094626, mm^3
# Measure non-WM-hypointensities, 90.822737, mm^3
# Measure 5th-Ventricle, 16.024828, mm^3
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