External Email - Use Caution
Hello Freesurfer experts,
I am attempting to run the command
mri_glmfit --y lh.RBS_ADRC_N0_control.10.mgh --fsgd RBS_ADRC_APOE_age22.fsgd
dods --C APOE_ageINT.mtx --surf fsaverage lh --cortex --glmdir
lh.RBS_ADRC_N0.glmdir
On this .fsgd file:
“RBS_ADRC_APOE_age22.txt”
Using the following design matrix:
“lh.RBS_ADRC_N0.txt”
I am receiving the error message:
--------------------------------
ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08
--------------------------------
Possible problem with experimental design:
Check for duplicate entries and/or lack of range of
continuous variables within a class.
I would appreciate your insights into what may be the likely cause of this
error and apologize that the files are in text format. If need be, I can
convert these to their proper formats.
misc information:
Freesurfer 6.00
CentOS v7
Best,
Curtis
GroupDescriptorFile 1
Title RBS_ADRC_APOE_age2_sex_control
Class FE4neg1
Class FE4pos1
Class FE4neg2
Class FE4pos2
Class ME4neg1
Class ME4pos1
Class ME4neg2
Class ME4pos2
Variables Age Age2
Input FSURF_RBS01LJ00635_20150619_121551_20150619.121551_1 FE4pos1
-1.316730879 1.733780208
Input FSURF_RBS01LJ04931_20140410_123922_20140410.123922_1 FE4pos1
-5.216730879 27.21428106
Input FSURF_RBS01LJ05491_20150522_120949_20150522.120949_1 FE4pos1
11.88326912 141.212085
Input FSURF_RBS01LJ00357_20140528_123655_20140528.123655_1 FE4neg1
-5.616730879 31.54766577
Input FSURF_RBS01LJ02140_20140612_121718_20140612.121718_1 FE4neg1
-5.716730879 32.68101194
Input FSURF_RBS01LJ03496_20140812_121641_20140812.121641_1 FE4neg1
-0.716730879 0.513703153
Input FSURF_RBS01LJ04399_20150624_115927_20150624.115927_1 FE4neg1
3.083269121 9.506548473
Input FSURF_RBS01LJ04474_20140710_121401_20140710.121401_1 FE4neg1
-3.316730879 11.00070372
Input FSURF_RBS01LJ04692_20140910_124909_20140910.124909_1 FE4neg1
-2.416730879 5.840588141
Input FSURF_RBS01LJ04841_20150107_121028_20150107.121028_1 FE4neg1
8.183269121 66.96589351
Input FSURF_ADRC3047_20150204_161246_20150204.161246_1 FE4neg1
-11.21673088 125.8150516
Input FSURF_ADRC3537_20150415_141949_20150415.141949_1 FE4neg1
3.783269121 14.31312524
Input FSURF_RBS01LJ02603_20151007_121518_20151007.121518_1 FE4pos1
8.483269121 71.96585498
Input FSURF_RBS01LJ03097_20151209_120245_20151209.120245_1 FE4pos1
10.08326912 101.6723162
Input FSURF_RBS01LJ03591_20140820_124751_20140820.124751_1 FE4pos1
-3.516730879 12.36739608
Input FSURF_RBS01LJ03597_20160323_120518_20160323.120518_1 FE4pos1
3.983269121 15.86643289
Input FSURF_RBS01LJ04191_20160527_120933_20160527.120933_1 FE4pos1
-4.316730879 18.63416548
Input FSURF_RBS01LJ04226_20150114_121418_20150114.121418_1 FE4pos1
-0.816730879 0.667049329
Input FSURF_RBS01LJ04471_20150902_123724_20150902.123724_1 FE4pos1
0.783269121 0.613510516
Input FSURF_RBS01LJ04972_20160608_105227_20160608.105227_1 FE4pos1
5.183269121 26.86627878
Input FSURF_RBS01LJ05204_20150923_120105_20150923.120105_1 FE4pos1
-1.016730879 1.03374168
Input FSURF_RBS01LJ06014_20150612_115706_20150612.115706_1 FE4pos1
-3.216730879 10.34735755
Input FSURF_RBS01LJ06333_20150821_115630_20150821.115630_1 FE4pos1
5.683269121 32.2995479
Input FSURF_140116cw015_20140116_095920_20140116.095920_1 FE4pos1
-7.216730879 52.08120458
Input FSURF_140716cw019_20140716_103307_20140716.103307_1 FE4pos1
-3.216730879 10.34735755
Input FSURF_150430cw025_20150430_121606_20150430.121606_1 FE4pos1
-8.216730879 67.51466634
Input FSURF_ADRC3351_20170522_124419_20170522.124419_1 FE4pos1
0.783269121 0.613510516
Input FSURF_ADRC3383_20130425.100851_1 FE4pos1 3.783269121
14.31312524
Input FSURF_ADRC3564_20170713_101052_20170713.101052_1 FE4pos1
-1.216730879 1.480434032
Input FSURF_ADRC3572_20170605_115303_20170605.115303_1 FE4pos1
-6.216730879 38.64774282
Input FSURF_ADRC3748_20210702_115232_20210702.115232_1 FE4pos2
-1.916730879 3.673857262
Input FSURF_ADRC3828_20201102_145018_20201102.145018_1 FE4pos2
-3.916730879 15.34078078
Input FSURF_ADRC3834_20201027_143411_20201027.143411_1 FE4pos2
-2.316730879 5.367241966
Input FSURF_ADRC8092_20130418.111516_1 FE4pos1 1.783269121
3.180048758
Input FSURF_RBSBDV100155_20150715_120042_20150715.120042_1 FE4pos1
13.18326912 173.7985847
Input FSURF_RBSBDV100193_20150506_111413_20150506.111413_1 FE4pos1
12.28326912 150.8787003
Input FSURF_RBSD1LJ00018_20160713_115259_20160713.115259_1 FE4pos1
-15.51673088 240.7689372
Input FSURF_RBSR02J00518_20160525_122715_20160525.122715_1 FE4pos1
-3.616730879 13.08074225
Input FSURF_RBSV1LJ00507_20160127_115959_20160127.115959_1 FE4pos1
10.28326912 105.7456238
Input FSURF_RBSV1LJ00526_20141212_111046_20141212.111046_1 FE4pos1
0.283269121 0.080241395
Input FSURF_RBS01LJ00091_20150911_111339_20150911.111339_1 FE4neg1
9.583269121 91.83904705
Input FSURF_RBS01LJ00164_20150410_104001_20150410.104001_1 FE4neg1
-4.416730879 19.50751166
Input FSURF_RBS01LJ00306_20141212_121346_20141212.121346_1 FE4neg1
-7.416730879 55.00789693
Input FSURF_RBS01LJ00317_20141105_123305_20141105.123305_1 FE4neg1
-1.316730879 1.733780208
Input FSURF_RBS01LJ00468_20140813_123403_20140813.123403_1 FE4neg1
-3.516730879 12.36739608
Input FSURF_RBS01LJ00619_20140807_124633_20140807.124633_1 FE4neg1
-0.916730879 0.840395505
Input FSURF_RBS01LJ01301_20150527_115654_20150527.115654_1 FE4neg1
14.68326912 215.5983921
Input FSURF_RBS01LJ01777_20160422_115348_20160422.115348_1 FE4neg1
-6.816730879 46.46781988
Input FSURF_RBS01LJ01853_20140415_123921_20140415.123921_1 FE4neg1
-13.41673088 180.0086675
Input FSURF_RBS01LJ02061_20150605_140834_20150605.140834_1 FE4neg1
-5.216730879 27.21428106
Input FSURF_RBS01LJ02190_20160122_115103_20160122.115103_1 FE4neg1
-0.916730879 0.840395505
Input FSURF_RBS01LJ02338_20140513_122958_20140513.122958_1 FE4neg1
-4.816730879 23.20089636
Input FSURF_RBS01LJ02350_20140521_123432_20140521.123432_1 FE4neg1
19.48326912 379.5977756
Input FSURF_RBS01LJ02484_20160506_112352_20160506.112352_1 FE4neg1
-3.116730879 9.714011372
Input FSURF_RBS01LJ02501_20140827_121901_20140827.121901_1 FE4neg1
-4.816730879 23.20089636
Input FSURF_RBS01LJ02661_20141119_131254_20141119.131254_1 FE4neg1
-1.216730879 1.480434032
Input FSURF_RBS01LJ02915_20160316_115408_20160316.115408_1 FE4neg1
-6.216730879 38.64774282
Input FSURF_RBS01LJ03061_20160217_122244_20160217.122244_1 FE4neg1
1.183269121 1.400125813
Input FSURF_RBS01LJ03232_20151028_125157_20151028.125157_1 FE4neg1
7.783269121 60.57927821
Input FSURF_RBS01LJ03318_20160205_115709_20160205.115709_1 FE4neg1
1.183269121 1.400125813
Input FSURF_RBS01LJ04182_20160603_120109_20160603.120109_1 FE4neg1
-14.81673088 219.5355139
Input FSURF_RBS01LJ04198_20150220_120148_20150220.120148_1 FE4neg1
4.083269121 16.67308671
Input FSURF_RBS01LJ04287_20140821_124250_20140821.124250_1 FE4neg1
-3.416730879 11.6740499
Input FSURF_RBS01LJ04364_20160330_115439_20160330.115439_1 FE4neg1
2.283269121 5.213317879
Input FSURF_RBS01LJ04476_20150218_115458_20150218.115458_1 FE4neg1
3.983269121 15.86643289
Input FSURF_RBS01LJ04618_20150515_110410_20150515.110410_1 FE4neg1
-1.016730879 1.03374168
Input FSURF_RBS01LJ04627_20140918_114906_20140918.114906_1 FE4neg1
-2.916730879 8.50731902
Input FSURF_RBS01LJ04700_20150508_121040_20150508.121040_1 FE4neg1
-3.216730879 10.34735755
Input FSURF_RBS01LJ04927_20150306_115244_20150306.115244_1 FE4neg1
0.783269121 0.613510516
Input FSURF_RBS01LJ05290_20140520_124627_20140520.124627_1 FE4neg1
-12.51673088 156.6685519
Input FSURF_RBS01LJ05819_20150408_104652_20150408.104652_1 FE4neg1
1.083269121 1.173471989
Input FSURF_RBS01LJ05878_20151216_120029_20151216.120029_1 FE4neg1
4.083269121 16.67308671
Input FSURF_RBS01LJ05972_20141205_122637_20141205.122637_1 FE4neg1
0.983269121 0.966818164
Input FSURF_RBS01LJ05990_20140409_125014_20140409.125014_1 FE4neg1
-6.116730879 37.41439665
Input FSURF_RBS01LJ06026_20150617_111835_20150617.111835_1 FE4neg1
-3.516730879 12.36739608
Input FSURF_130815cw002_20130815_105335_20130815.105335_1 FE4neg1
-7.216730879 52.08120458
Input FSURF_ADRC3412_20210430_135006_20210430.135006_1 FE4neg2
1.383269121 1.913433461
Input FSURF_ADRC3588_20170711_101058_20170711.101058_1 FE4neg1
-0.216730879 0.046972274
Input FSURF_ADRC3757_20211102_135734_20211102.135734_1 FE4neg2
-1.679744578 2.821541846
Input FSURF_ADRC3851_20211221_112829_20211221.112829_1 FE4neg2
-1.123580194 1.262432452
Input FSURF_ADRC8137_20150206_145758_20150206.145758_1 FE4neg1
8.783269121 77.14581645
Input FSURF_BBB001_20220503_151815_20220503.151815_1 FE4neg2 -10.20577197
104.1577816
Input FSURF_RBS01LJ03006_20160617_104608_20160617.104608_1 FE4pos1
-5.316730879 28.26762724
Input FSURF_RBS01LJ03738_20160617_114857_20160617.114857_1 FE4pos1
-17.31673088 299.8691683
Input FSURF_RBS01LJ06270_20150121_121845_20150121.121845_1 FE4pos1
4.683269121 21.93300966
Input FSURF_RBS01LJ06323_20140730_125445_20140730.125445_1 FE4pos1
-1.016730879 1.03374168
Input FSURF_RBS01LJ06331_20140903_125402_20140903.125402_1 FE4pos1
-3.516730879 12.36739608
Input FSURF_ADRC2634_20130425.141123_1 FE4pos1 4.783269121
22.87966348
Input FSURF_ADRC3257_20150731_142304_20150731.142304_1 FE4pos1
1.783269121 3.180048758
Input FSURF_ADRC3759_20210707_131821_20210707.131821_1 FE4pos2
-4.616730879 21.31420401
Input FSURF_ADRC3779_20211005_142630_20211005.142630_1 FE4pos2
0.183269121 0.033587571
Input FSURF_RBS01LJ00504_20160108_110442_20160108.110442_1 FE4neg1
3.883269121 15.07977907
Input FSURF_RBS01LJ01885_20140213_124057_20140213.124057_1 FE4neg1
-4.816730879 23.20089636
Input FSURF_RBS01LJ01985_20141114_121221_20141114.121221_1 FE4neg1
0.183269121 0.033587571
Input FSURF_RBS01LJ02258_20150529_120557_20150529.120557_1 FE4neg1
-0.216730879 0.046972274
Input FSURF_RBS01LJ03293_20151118_120348_20151118.120348_1 FE4neg1
11.38326912 129.5788159
Input FSURF_RBS01LJ03583_20160408_115730_20160408.115730_1 FE4neg1
-8.316730879 69.16801251
Input FSURF_RBS01LJ03877_20150320_115330_20150320.115330_1 FE4neg1
1.583269121 2.50674111
Input FSURF_RBS01LJ04829_20160331_113751_20160331.113751_1 FE4neg1
-4.316730879 18.63416548
Input FSURF_RBS01LJ05281_20151022_102545_20151022.102545_1 FE4neg1
7.383269121 54.51266291
Input FSURF_RBS01LJ05449_20160706_120010_20160706.120010_1 FE4neg1
-12.41673088 154.1752057
Input FSURF_RBS01LJ05501_20140423_115304_20140423.115304_1 FE4neg1
3.283269121 10.77985612
Input FSURF_RBS01LJ05635_20140911_124649_20140911.124649_1 FE4neg1
-6.416730879 41.17443517
Input FSURF_RBS01LJ05748_20140312_124653_20140312.124653_1 FE4neg1
0.883269121 0.78016434
Input FSURF_RBS01LJ05907_20150304_115018_20150304.115018_1 FE4neg1
4.083269121 16.67308671
Input FSURF_RBS01LJ06259_20160304_115101_20160304.115101_1 FE4neg1
-8.716730879 75.98139722
Input FSURF_140708cw018_20140708_103713_20140708.103713_1 FE4neg1
2.783269121 7.746587
Input FSURF_ADRC3342_20130404.111429_1 FE4neg1 -1.216730879
1.480434032
Input FSURF_ADRC3461_20170619_113842_20170619.113842_1 FE4neg1
-6.216730879 38.64774282
Input FSURF_ADRC3551_20170905_141603_20170905.141603_1 FE4neg1
6.783269121 46.01273997
Input FSURF_ADRC3601_20210208_133217_20210208.133217_1 FE4neg2
3.283269121 10.77985612
Input FSURF_ADRC3703_20200922_133743_20200922.133743_1 FE4neg2
-6.844128139 46.84208999
Input FSURF_ADRC3732_20200918_135302_20200918.135302_1 FE4neg2
-4.137278824 17.11707607
Input FSURF_ADRC3736_20220412_125703_20220412.125703_1 FE4neg2
-3.09892266 9.603321652
Input FSURF_ADRC3765_20210728_131319_20210728.131319_1 FE4neg2
-2.216730879 4.91389579
Input FSURF_RBSBDV100223_20150429_120910_20150429.120910_1 FE4neg1
15.18326912 230.5316612
Input FSURF_RBSV1LJ00557_20150424_121352_20150424.121352_1 FE4neg1
-1.316730879 1.733780208
Input FSURF_RBS01LJ04458_20150204_113710_20150204.113710_1 FE4neg1
3.983269121 15.86643289
Input FSURF_ADRC3608_20220503_131319_20220503.131319_1 FE4neg2
4.91477597 24.15502284
Input FSURF_RBS01LJ00424_20150325_104510_20150325.104510_1 ME4pos1
6.483269121 42.0327785
Input FSURF_RBS01LJ00514_20150604_095117_20150604.095117_1 ME4pos1
6.483269121 42.0327785
Input FSURF_RBS01LJ04477_20150218_105622_20150218.105622_1 ME4pos1
-16.21673088 262.9823604
Input FSURF_RBS01LJ04517_20150624_105834_20150624.105834_1 ME4pos1
6.583269121 43.33943232
Input FSURF_RBS01LJ04965_20140917_121934_20140917.121934_1 ME4pos1
-1.916730879 3.673857262
Input FSURF_RBS01LJ05872_20160624_113547_20160624.113547_1 ME4pos1
-3.016730879 9.100665196
Input FSURF_RBS01LJ06171_20140709_124427_20140709.124427_1 ME4pos1
20.98326912 440.297583
Input FSURF_RBS01LJ03740_20150729_112412_20150729.112412_1 ME4neg1
7.683269121 59.03262439
Input FSURF_RBS01LJ05297_20160323_105811_20160323.105811_1 ME4neg1
7.883269121 62.14593203
Input FSURF_ADRC3389_20150410_140549_20150410.140549_1 ME4neg1
-1.216730879 1.480434032
Input FSURF_RBS01LJ00181_20150911_120634_20150911.120634_1 ME4pos1
9.983269121 99.66566234
Input FSURF_RBS01LJ00503_20160108_120205_20160108.120205_1 ME4pos1
4.283269121 18.34639436
Input FSURF_RBS01LJ00917_20140226_125128_20140226.125128_1 ME4pos1
-3.616730879 13.08074225
Input FSURF_RBS01LJ01913_20140326_125049_20140326.125049_1 ME4pos1
-3.216730879 10.34735755
Input FSURF_RBS01LJ03225_20151113_105550_20151113.105550_1 ME4pos1
6.683269121 44.66608614
Input FSURF_RBS01LJ03748_20140514_121615_20140514.121615_1 ME4pos1
-8.416730879 70.84135869
Input FSURF_RBS01LJ03974_20141121_111546_20141121.111546_1 ME4pos1
0.183269121 0.033587571
Input FSURF_RBS01LJ04680_20150417_115910_20150417.115910_1 ME4pos1
-1.316730879 1.733780208
Input FSURF_RBS01LJ04735_20150116_110340_20150116.110340_1 ME4pos1
-7.116730879 50.6478584
Input FSURF_RBS01LJ04809_20150603_121726_20150603.121726_1 ME4pos1
16.48326912 271.6981609
Input FSURF_RBS01LJ05201_20150128_121827_20150128.121827_1 ME4pos1
4.583269121 21.00635584
Input FSURF_RBS01LJ05203_20150923_104940_20150923.104940_1 ME4pos1
-0.916730879 0.840395505
Input FSURF_RBS01LJ05634_20140911_114909_20140911.114909_1 ME4pos1
-2.916730879 8.50731902
Input FSURF_RBS01LJ05672_20150403_113903_20150403.113903_1 ME4pos1
2.083269121 4.340010231
Input FSURF_RBS01LJ06127_20160304_103835_20160304.103835_1 ME4pos1
-4.216730879 17.78081931
Input FSURF_ADRC3347_20150320_140834_20150320.140834_1 ME4pos1
5.783269121 33.44620173
Input FSURF_ADRC3665_20211020_130037_20211020.130037_1 ME4pos2
7.013406107 49.18786523
Input FSURF_ADRC3826_20210623_150011_20210623.150011_1 ME4pos2
2.383269121 5.679971703
Input FSURF_ADRC8238_20150729_141855_20150729.141855_1 ME4pos1
-2.216730879 4.91389579
Input FSURF_RBS01LJ00505_20151202_120905_20151202.120905_1 ME4neg1
7.683269121 59.03262439
Input FSURF_RBS01LJ00634_20150619_105909_20150619.105909_1 ME4neg1
-1.116730879 1.247087856
Input FSURF_RBS01LJ01716_20160212_121103_20160212.121103_1 ME4neg1
3.483269121 12.13316377
Input FSURF_RBS01LJ02017_20160511_114537_20160511.114537_1 ME4neg1
-20.01673088 400.6695151
Input FSURF_RBS01LJ02500_20140827_112012_20140827.112012_1 ME4neg1
-3.916730879 15.34078078
Input FSURF_RBS01LJ02990_20160316_104954_20160316.104954_1 ME4neg1
-5.516730879 30.43431959
Input FSURF_RBS01LJ04470_20150902_113448_20150902.113448_1 ME4neg1
9.183269121 84.33243175
Input FSURF_RBS01LJ04610_20150717_104459_20150717.104459_1 ME4neg1
11.48326912 131.8654697
Input FSURF_RBS01LJ04876_20150225_104947_20150225.104947_1 ME4neg1
4.283269121 18.34639436
Input FSURF_RBS01LJ05216_20140625_122850_20140625.122850_1 ME4neg1
-14.31673088 204.9687831
Input FSURF_RBS01LJ05406_20140507_124234_20140507.124234_1 ME4neg1
-0.116730879 0.013626098
Input FSURF_RBS01LJ05490_20150522_110259_20150522.110259_1 ME4neg1
13.18326912 173.7985847
Input FSURF_RBS01LJ05500_20140423_125302_20140423.125302_1 ME4neg1
6.283269121 39.47947085
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