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FreeSurfer does not need ACPC alignment to be done.  It does benefit from 
on-scanner B1- correction such as “Pre-Scan Normalize” on Siemens scanners.

Matt.

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Toshiharu 
Kamishikiryo <k5105...@gmail.com>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Sunday, April 23, 2023 at 4:46 PM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] ACPC alignment and RF/B1 bias correction before processing



        External Email - Use Caution
Hello Freesurfer experts

Would it be more accurate to apply ACPC alignment and RF/B1 bias correction to 
T1w.nii.gz before recon-all to improve pial estimation accuracy?

Thanks in advance

Regards
Kamishikiryo
Research Student

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