yes, it is the same contrast
On 11/20/2023 3:30 PM, Laura Willers de Souza wrote:
External Email - Use Caution
Great, thanks so much!
But I am having difficulty understanding how to construct the contrast
to answer the following question "Is the interaction between group
(CU/CI) and cortisol significant regressing out the effect of sex,
age, APOE_carrier, abeta and ptau?" It seems like the contrast would
be the same as before.. Can you help me with this?
Thanks again!
*Laura Willers de Souza *
PhD Student in Pharmacology and Therapeutics
Zimmer Lab - Federal University of Rio Grande do Sul
- Porto Alegre/RS - Brazil
-----
Douglas N. Greve
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Wed, 15 Nov 2023 06:54:36 -0800
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Yes, that looks right (assuming that cortisol is your first variable)
---- On 11/7/2023 3:49 PM, Laura Willers de Souza wrote:
External Email - Use Caution Hello FreeSurfer Developers,
Following the FSGD examples on the website, I built the following test:
Question: Is there an association between cortisol and cortical
thickness regressing out the effect of sex, age, APOE4_carrier (1=1 or
2 alleles, 0=no alleles), abeta, ptau, diagnosis (CU and CI)?
Regressors: 2 factors (sex, diagnosis) with 2 levels each, 5
covariates (age, APOE4_carrier (1=1 or 2 alleles, 0=no alleles),
abeta, ptau, cortisol) >> 24 regressors
Contrast: 0 0 0 0 0.5 -0.5 0.5 -0.5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
FSGD: GroupDescriptorFile 1 Title CSF_semgrupos Class MaleCU Class
MaleCI Class FemaleCU Class FemaleCI Variables Cortisol Age ABETA ptau
APOE4_carrier Input 098_S_4003_I224603 MaleCI 11 81.3 741.5 22.83 1
Does this feel right to you?
I am having difficulty understanding how to construct the contrast to
answer the following question "Is the interaction between group
(CU/CI) and cortisol significant regressing out the effect of sex,
age, APOE_carrier, abeta and ptau?" It seems like the contrast would
be the same as before.. Can you guys help me with this?
Thanks in advance! *Laura Willers de Souza * PhD Student in
Pharmacology and Therapeutics Zimmer Lab - Federal University of Rio
Grande do Sul - Porto Alegre/RS - Brazil
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