External Email - Use Caution
Hi Douglas,
Thanks for your clarification. This is my first time to run PetSurfer. We did
want to normalize by cerebellar grey matter, and I will add the "--rescale 8
47". I just copied "6" from the example command. I know "6" should be the FWHM
of the point-spread function (PSF) of the scanner as measured in image space. I
did ask the technician at the PET centre, and he replied that the
reconstruction method was "OP-OSEM 8i21s" and the filter was "XYZ gaussian
2.00". Can I use "2" for psf in the command?
Thanks,
Angel
________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu
<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Douglas N. Greve
<dgr...@mgh.harvard.edu>
Sent: Thursday, March 21, 2024 9:44 PM
To: freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: Can kinetic modeling be applied to PET
data with single frame?
Yes, though that will normalize by the pons. If you want to normalize by
something else, you will need to specify it with --rescale. Eg, if you want to
normalize by ceberbellar gray matter, add
--rescale 8 47
Where did you get "6" from for the psf?
On 3/20/2024 10:57 PM, WONG Wan Wa wrote:
External Email - Use Caution
Hi Douglas,
Thanks for your reply. We used different tracers for diagnosis of AD or other
neurodegenerative diseases, including PIB, FDG, Flutemetamol and TAU. If an SUV
analysis is used, is it done by mri_gtmpvc? Is there any subsequent analysis
needed?
This is my mri_gtmpvc command:
mri_gtmpvc \
--i
$SUBJECTS_DIR/sub-QM001/pet/sub-QM001_ses-001_trc-C11PIB_rec-05MINS_run-001_pet.nii.gz
\
--reg
$SUBJECTS_DIR/sub-QM001/pet/sub-QM001_ses-001_trc-C11PIB_rec-05MINS_run-001_pet.reg.lta
\
--psf 6 \
--seg $SUBJECTS_DIR/sub-QM001/mri/gtmseg.mgz \
--default-seg-merge \
--auto-mask 1 .01 \
--mgx .01 \
--o $SUBJECTS_DIR/sub-QM001/pet/gtmpvc.output
Is this command okay?
Thanks,
Angel
________________________________
From:
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
on behalf of Douglas N. Greve
<dgr...@mgh.harvard.edu><mailto:dgr...@mgh.harvard.edu>
Sent: Wednesday, March 20, 2024 11:27 PM
To: freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: Can kinetic modeling be applied to PET
data with single frame?
you cannot apply kinetic modeling to one frame. What is you ligand? For a one
frame acquisition, you usually use an SUV analysis.
On 3/20/2024 12:03 AM, WONG Wan Wa wrote:
External Email - Use Caution
Hi experts,
As stated in the subject, can kinetic modeling be applied to PET data with only
one frame? Or we just stop at ROI analysis without kinetic modeling?
Best,
Angel
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