External Email - Use Caution Dear Douglas,
Thank you for your kind help and advice! Good to know that a two-stage model is not needed for one subject. So I should not run the longitudinal preprocessing either, right? Following your advice, I created this FSGD file below for subjid1 with 5 timepoints (0, 3, 6, 9, 12). Name of the imaging files: subjid1_base, subjid1_3mo, subjid1_6mo, subjid1_9mo, subjid1_12mo GroupDescriptorFile 1 Title Onesubject Class Class1 Variables TimePoint Input subjid1_base Class1 0 Input subjid1_3mo Class1 3 #Input subjid1_6mo Class1 6 Input subjid1_9mo Class1 9 Input subjid1_12mo Class1 12 Does this look okay to you? You also wrote that I should "remove the mean of the time points from the time point number number". (The mean is 6 in our case) I wonder why? Does this mean that the TimePoint variables should be -6 -3 0 3 6 instead? (and not 0 3 6 9 12) GroupDescriptorFile 1 Title Onesubject Class Class1 Variables TimePoint Input subjid1_base Class1 -6 Input subjid1_3mo Class1 -3 #Input subjid1_6mo Class1 0 Input subjid1_9mo Class1 3 Input subjid1_12mo Class1 6 Sincerely, Isa Rosselini On Thu, Apr 17, 2025 at 5:37 PM Isabella Rossellini <[email protected]> wrote: > > Dear Douglas, > > I am sorry for the late response. I did not see your message up until now. > I would like to see how the brain changes for a patient with anxiety > who got better gradually (again, we have 5-time points (0, 3, 6, 9, > 12). And then do the same for another participant who did not get > better up until 12 months. > That is the reason I would like to look at patients one by one. > > I ran the mri_glmfit analysis but I received an error message: > > ERROR: DOF=0 > > Is this because I tried to run it on one participant? > > Sincerely, > Isa Rosselini > > Date: Mon, 3 Feb 2025 09:20:40 -0500 > From: "Douglas N. Greve" <[email protected]> > Subject: Re: [Freesurfer] longitudinal analysis on one subject > To: [email protected] > Message-ID: <[email protected]> > Content-Type: text/plain; charset="utf-8" > > The glm can be run on this data in theory. With only 5 time points, you > probably won't have much power though. What are you trying to test? > > On Sat, Feb 1, 2025 at 11:56 PM Isabella Rossellini > <[email protected]> wrote: > > > > Hello Freesurfer users/experts, > > > > I am working with Freesurfer 7.4.1 on a MacStudio (macOS 15.2) and I would > > like to ask your opinion about the following. > > > > Basically, we had an anxiety treatment study and I would like to analyze > > one subject who has 5-time points (0, 3, 6, 9, 12) with a longitudinal > > pipeline, two-stage model. > > Is it possible to run this on one person only and see the changes between > > these time points? > > > > I have never done this before on one subject so I am not sure what the best > > approach would be to look at the changes. > > After running the longitudinal preprocessing (base, long), should I > > generate the tables of freesurfer parcellation/segmentation stats data > > (aparcstats2table, asegstats2table)? > > Or can I just follow the two stage model steps? Maybe glm only works on a > > group of subjects. > > https://secure-web.cisco.com/1PBrCxPtnV_cyA4wjTbApPKLTn7-VE-boLvlA7ZOq8U2_gMV3mVfwQW400P-AE4blknStdaEUX25IhFSt8AiV9yKnPhcMfMsvDVhYBDCWINUX4zFR9AFCp1Nji_lfI_mAeWZRm2W83Uw_qjKJGBEXYTF9O2jJ7oVZLqWa7nrfPGfIZ-Smi4A52OI_0-Ug7qyllBjyrVvncJf0ytOeKlGbgX4LTbfpae9BzVf4ZD-yNFUdSGTJVdehj4I6Tq9OQLYN0ETVRr7-z_K8Z0UEJM1jZnkWLYTRmUX6PPXhAAgTbotdvGBvMC4nJYm2UG4qVLMmfsH2VuMVHFRqAPc_S6p9Yw/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FLongitudinalTwoStageModel > > > > (We have 9 more subjects - 10 in total - so I was hoping to visualize the > > pattern of changes one by one, in each subject, since these patients showed > > different changes in anxiety based on self-reported > > questionnaires) > > > > Sincerely, > > Isa Rosselini > > _______________________________________________ Freesurfer mailing list -- [email protected] To unsubscribe send an email to [email protected] https://mail.nmr.mgh.harvard.edu/mailman3/lists/[email protected]/ The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at https://www.massgeneralbrigham.org/complianceline <https://www.massgeneralbrigham.org/complianceline> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
