External Email - Use Caution They just described this regarding the ICC in their methods section: "For the present study, intrinsic cortical curvature was calculated using Gaussian curvature calculations in the following regions of interest from both the left (LH) and right (RH) hemispheres: the caudal anterior cingulate cortex (henceforth “ACC”), the rostral middle frontal cortex (henceforth “DLPFC”), the superior parietal region (henceforth “parietal cortex”), and the superior temporal region (henceforth “temporal cortex”). The regions of ICC quantification were chosen from their delineation atlas, the Desikan-Killiany cortical atlas (Desikan et al., 2006), for their approximation to regions of observed glutamatergic dysregulation (Iwata et al., 2019; Shah et al., 2020b) and structural decline (Anderson et al., 2015; Bodnar et al., 2010; Fan et al., 2023; Wannan et al., 2019) in available literature."
Thanks, Vittal On Wed, Jul 23, 2025 at 3:50 PM <[email protected]> wrote: > Send Freesurfer mailing list submissions to > [email protected] > > To subscribe or unsubscribe via email, send a message with subject or > body 'help' to > [email protected] > > You can reach the person managing the list at > [email protected] > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Freesurfer digest..." > > Today's Topics: > > 1. Inquiry Regarding Intrinsic Cortical Curvature (ICC) Calculation in > FreeSurfer > (vittal korann) > 2. Re: Inquiry Regarding Intrinsic Cortical Curvature (ICC) Calculation > in FreeSurfer > (Fischl, Bruce R.,PHD) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Wed, 23 Jul 2025 15:44:14 -0400 > From: vittal korann <[email protected]> > Subject: [Freesurfer] Inquiry Regarding Intrinsic Cortical Curvature > (ICC) Calculation in FreeSurfer > To: Freesurfer support list <[email protected]> > Message-ID: > <CACyMoT3Vps-CC9G= > [email protected]> > Content-Type: multipart/alternative; > boundary="000000000000b91b68063a9def84" > > External Email - Use Caution > > Dear FreeSurfer Team, > > I’m currently working on a project involving cortical morphology and am > particularly interested in calculating Intrinsic Cortical Curvature (ICC) > using FreeSurfer. > > I came across a recent publication ( > > https://secure-web.cisco.com/1oL8IZPRfQ5o5UDqVHfF8rU4SLPTHeXEdS4OHOftgKkxaXnXs_JcjgvX9Pe6OjBAkg-u6fxy2Cx-D41wHlEOMEUS_Tk4d7v7Qx3Likv_shYeRtBnydcyfIwu-HBDJKzLVej16EUEX-HNd8WGxTf7Ghvp8It6AivG6yuekw2Fms7MQqM2usIj69bSUOCgHXEJVNndJssFPN8-cnhlMpo8F3l1h9DmbUW45d2fUw_JIGOzVK4lBhAakU7epXVGW1WTQ80Aykb2L7XDlPgosOWOufDrB0xiUu0Tc0OmbMxmp5guJBLGRXwomIYU_9p_795vNmXJLXjWb0vLGetc7x5nWPw/https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F38761434%2F) > that utilized ICC in their > statistical analysis. I’d like to clarify a couple of points regarding how > ICC is derived within the FreeSurfer framework: > > 1. Is Gaussian curvature as computed by FreeSurfer considered equivalent to > ICC? > > 2. If not, are there additional steps or specific tools required to compute > ICC beyond the standard curvature outputs (e.g., via mris_curvature or > mris_curvature_stats)? > > Any guidance or documentation you could share would be greatly appreciated. > I’m aiming to ensure methodological consistency with published work and > would be grateful for your insights. > > Thank you for your time and support. > > With regards, > Vittal > -------------- next part -------------- > A message part incompatible with plain text digests has been removed ... > Name: not available > Type: text/html > Size: 3036 bytes > Desc: not available > > ------------------------------ > > Message: 2 > Date: Wed, 23 Jul 2025 19:49:47 +0000 > From: "Fischl, Bruce R.,PHD" <[email protected]> > Subject: [Freesurfer] Re: Inquiry Regarding Intrinsic Cortical > Curvature (ICC) Calculation in FreeSurfer > To: Freesurfer support list <[email protected]> > Message-ID: <[email protected] > prd04.prod.outlook.com> > Content-Type: multipart/alternative; boundary="_000_DM5PR04MB126142 > 7D8F3DADE6FD8C37DEEF5FADM5PR04MB1261namp_" > > Sorry, what is their definition of ICC? Certainly Gaussian Curvature is an > intrinsic geometric measure of curvature, but not sure if that is what they > mean > > From: vittal korann <[email protected]> > Sent: Wednesday, July 23, 2025 3:44 PM > To: Freesurfer support list <[email protected]> > Subject: [Freesurfer] Inquiry Regarding Intrinsic Cortical Curvature (ICC) > Calculation in FreeSurfer > > > External Email - Use Caution > Dear FreeSurfer Team, > > I’m currently working on a project involving cortical morphology and am > particularly interested in calculating Intrinsic Cortical Curvature (ICC) > using FreeSurfer. > > I came across a recent publication ( > https://secure-web.cisco.com/1-UbYW5YOKtHO1qd9O61dhUh5cyQZurOOYLYojZIKRajJtUfJfudoTO0pOdSRujMbECUl7qtZm5FPT7VJGhuZMEoaQfNGSG6HKOCmHu2vkSlXP6tBq6ObkvPfswSfc8Dtp4o6uDVpJtBMlp33NL86k3nSSGD9KnVprHrGCPENFArXya7DGbYujQetvhjMWSCA_kPjIf0mVILV5K5y4UZ1NiWjnSX-Q2bCShItcOmYpdfRDWTDz8lebOEsGgSFulDYpWn8pX84yq0XqZF2AcHwZe377Bh7AV3MVN9SgbL_uJGyRffcMaPiOktIk6Y5kZ0LFnWfNebVzLZL8o25ahQZ0A/https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F38761434%2F< > https://secure-web.cisco.com/1oL8IZPRfQ5o5UDqVHfF8rU4SLPTHeXEdS4OHOftgKkxaXnXs_JcjgvX9Pe6OjBAkg-u6fxy2Cx-D41wHlEOMEUS_Tk4d7v7Qx3Likv_shYeRtBnydcyfIwu-HBDJKzLVej16EUEX-HNd8WGxTf7Ghvp8It6AivG6yuekw2Fms7MQqM2usIj69bSUOCgHXEJVNndJssFPN8-cnhlMpo8F3l1h9DmbUW45d2fUw_JIGOzVK4lBhAakU7epXVGW1WTQ80Aykb2L7XDlPgosOWOufDrB0xiUu0Tc0OmbMxmp5guJBLGRXwomIYU_9p_795vNmXJLXjWb0vLGetc7x5nWPw/https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F38761434%2F>) > that utilized ICC in their statistical analysis. I’d like to clarify a > couple of points regarding how ICC is derived within the FreeSurfer > framework: > > 1. Is Gaussian curvature as computed by FreeSurfer considered equivalent > to ICC? > > 2. If not, are there additional steps or specific tools required to > compute ICC beyond the standard curvature outputs (e.g., via mris_curvature > or mris_curvature_stats)? > > Any guidance or documentation you could share would be greatly > appreciated. I’m aiming to ensure methodological consistency with published > work and would be grateful for your insights. > > Thank you for your time and support. > > With regards, > Vittal > > -------------- next part -------------- > A message part incompatible with plain text digests has been removed ... > Name: not available > Type: text/html > Size: 5515 bytes > Desc: not available > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Freesurfer mailing list -- [email protected] > To unsubscribe send an email to [email protected] > > https://secure-web.cisco.com/1QCmv8iVYlzVGjKt5Cz9UFcZ08IY-OtsVt_IJ07ej3Qwq-j3hFy_7ldiK2bmsNjxnn0O7M3xROqSfRB3KX8h00UDrifjOh4Ji5VmdN504M6jRezYuDxD5pJoxwOEkESztDI4qXTbRu4urrLWpaMJjRN1GEjxL65g1l3IHLIU1DNPeIAesBIOkX9VCY4z5xDYi9taLN6ZY78ZXxAxt8xPM37ZJkY_oxI0U2eySnsQ_U4ozC17mOlxl6q7jU1jDrXJuVKrZFQNlNeJlo908JxcTZdfA2JtR5BjrJlvTSXcd3_WsHzljKd5qOPIQwUkD2-8g_GJQ2APVQkCzV9347QkoBQ/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman3%2Flists%2Ffreesurfer%40nmr.mgh.harvard.edu%2F > > > ------------------------------ > > End of Freesurfer Digest, Vol 257, Issue 59 > ******************************************* > The information in this e-mail is intended only for the person to whom it > is addressed. If you believe this e-mail was sent to you in error and the > e-mail contains patient information, please contact the Mass General > Brigham Compliance HelpLine at > https://secure-web.cisco.com/16j-fQK89_CHKZvP1hHEbPAtxQe27CCt1fpsF7M4axzQCe2e52MGJd-7cPYaz5oRsipuwU_MPDQtSHGsJtpB-M4r-ofDs6BT76NH2bUA77PsE-0cmuToXOY70eq7LNlGQSbSjhPDe5keh5mTvZbhRma7wBEq6faNCnlGcHS0SzuFFN4KhihAxgjpnoz1HkfCCumlOw3mBOq22X-NKVv_9o-xCQKlO2baEfKpj7_M6n9iNGFMb--g3sJn-URUmZAgo-UuqBZDlCN61cxJ9E255JCnassu18LMZrw0v4r82hnpRIIUnaQ7b7jzeY5bsKEEmgytLAPeT9m5j5jQy5RL88g/https%3A%2F%2Fwww.massgeneralbrigham.org%2Fcomplianceline > < > https://secure-web.cisco.com/16j-fQK89_CHKZvP1hHEbPAtxQe27CCt1fpsF7M4axzQCe2e52MGJd-7cPYaz5oRsipuwU_MPDQtSHGsJtpB-M4r-ofDs6BT76NH2bUA77PsE-0cmuToXOY70eq7LNlGQSbSjhPDe5keh5mTvZbhRma7wBEq6faNCnlGcHS0SzuFFN4KhihAxgjpnoz1HkfCCumlOw3mBOq22X-NKVv_9o-xCQKlO2baEfKpj7_M6n9iNGFMb--g3sJn-URUmZAgo-UuqBZDlCN61cxJ9E255JCnassu18LMZrw0v4r82hnpRIIUnaQ7b7jzeY5bsKEEmgytLAPeT9m5j5jQy5RL88g/https%3A%2F%2Fwww.massgeneralbrigham.org%2Fcomplianceline> > . >
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