Dear UCSCers,

I'm interested in comparing the performance of various multiple genome 
alignment methods in a yeast 7-way genome alignment. This whole-genome 
alignment is precomputed and available in UCSC web
http://hgdownload.cse.ucsc.edu/goldenPath/sacCer2/multiz7way/

As far as I know, this alignment was created with the Penn State multiz 
alignment tool applied to pairwise alignments which are produced by a 
pipeline consisting of the Penn State blastz aligner, followed by the 
UCSC chain/net process. I would like to know if blastz pairwise local 
alignments used as input for the 7-way alignment are available somewhere 
through the UCSC web.  Could you provide me the BLASTZ parameters you 
used for the alignments, as well as the BLASTZ version? (BLASTZ was 
replaced by LASTZ, I don't know up to which point the results for each 
method are similar)

Thanks in advance,

Meri

-- 
Meritxell Oliva
PhD Student 
Comparative Bioinformatics Group
Bioinformatics and Genomics Programme
 
Centre de Regulacio Genomica (CRG)
Dr. Aiguader, 88
08003 Barcelona
Spain
 
email:  [email protected]

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