OK,  thanks guys.

On Tue, Oct 25, 2011 at 9:56 AM, Hiram Clawson <[email protected]> wrote:

> Good Morning Archie:
>
> Please note the difference in data value resolution between the values you
> obtain
> from the .wib files with hgWiggle, and the original ascii data values you
> find in
> the wigFix files.  Note the "Known issues section:" at
> http://genomewiki.ucsc.edu/**index.php/Wiggle<http://genomewiki.ucsc.edu/index.php/Wiggle>
>
> hgWiggle is the convenient query mechanism to work with the wiggle data
> sets with
> the caveat of the loss in resolution of the data values.  And yes, it can
> work on
> whole chromosome, or even whole genome queries.  The original ascii data
> files
> have the non-lossy data values, but they are simple ascii data files with
> no
> indexing available to allow convenient access.  If you have a spread sheet
> or R system
> which can handle a couple billion numbers in one table, you could perhaps
> throw all
> those numbers into that system.  I'm not familiar with what procedures you
> would use there
> to manipulate such a set of numbers.  See also:
> http://genomewiki.ucsc.edu/**index.php/Using_hgWiggle_**without_a_database<http://genomewiki.ucsc.edu/index.php/Using_hgWiggle_without_a_database>
>
> You could convert the wigFix files into bigWig files to avoid the loss of
> resolution.
> However, the query utilities into bigWig files are going to return ascii
> data values, or
> summaries in regions.  You would again need to manage the returned ascii
> data values.
> See also:  http://genomewiki.ucsc.edu/**index.php/Selecting_a_**
> graphing_track_data_format<http://genomewiki.ucsc.edu/index.php/Selecting_a_graphing_track_data_format>
>
> --Hiram
>
>
> Archie Russell wrote:
>
>> Thanks
>>
>> Will hgWiggle work for whole chromosomes?
>>
>> Could I also use the "wigFix" files (they are in ascii)
>>
>> Thanks,
>>  Archie
>>
>
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