#145: transform (ETL) GPC i2b2 data to PCORNet CDM
--------------------------+------------------------------
 Reporter:  dconnolly     |       Owner:  campbell
     Type:  enhancement   |      Status:  assigned
 Priority:  major         |   Milestone:  drn-basic-query
Component:  data-sharing  |  Resolution:
 Keywords:                |  Blocked By:  109
 Blocking:  160           |
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Changes (by ngraham):

 * owner:  ngraham => campbell


Comment:

 Dr. Cambell, at HackathonTwo, you agreed to supply a specific example of
 where that "path" approach to building the CDM breaks down (involving the
 SNOMET-CT hierarchy).  I may not be capturing it accurately, but I tried
 to create a very simplistic example.  Your specific (and clinically
 relevant) example will likely be a lot more helpful.

 == Details ==

 Dr. Campbell from UNMC brought up a case involving the SNOMED-CT hierarchy
 where he believes using i2b2 paths (current design approach - comment:3)
 breaks down for building the CDM (see [http://listserv.kumc.edu/pipermail
 /gpc-dev/2015q1/001117.html his e-mail on the gpc-dev list]).

 As I understand it, there are SNOMED-CT concept paths that depending on
 the parentage have different children.  In other words, CODE:1234 may have
 different codes associated with it depending on where it is in the
 hierarchy.

 For example, consider the following:
 {{{
 \i2b2\grandparent1\parent1\CODE:123\CODE:456\
 ..
 \i2b2\grandparent_ABC\parent_DEF\CODE:123\CODE:789\
 }}}

 A researcher wants to find all patients with CODE:123 and CODE:789.
 Knowledge of SNOMED-CT tells them that by selecting CODE:123 they should
 also get all patients with CODE:789 (as CODE:789 is a child of CODE:123
 the second path above).

 However, their i2b2 search used the first path above and therefore get
 patients with CODE:123 and CODE:456 instead.

 In another example, say the following path was used in i2b2:
 {{{
 \i2b2\grandparent_UVW\parent_XYZ\CODE:123\
 }}}

 In this case, the researcher _only_ gets patients with CODE:123 (when,
 again, given their knowledge of SNOMED-CT they should also have gotten
 patients with CODE:789).

 As I understand it from Dr. Campbell, a code may have 55 (or more)
 different places in the hierarchy each with their own set of children.

--
Ticket URL: 
<http://informatics.gpcnetwork.org/trac/Project/ticket/145#comment:19>
gpc-informatics <http://informatics.gpcnetwork.org/>
Greater Plains Network - Informatics
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