P via Development of GNU Guix and the GNU System distribution. 
<guix-devel@gnu.org> writes:

> Can we tell Guix that an input is runtime only? Or only needed in
> certain stages of the build?

We cannot and we cannot guarantee that the presence of a package during
the build isn’t going to affect the build outcome.

> For example, if a large package (let's
> say... written in Rust) uses Lua for a utility script at run time, but
> doesn't touch it at build time changing the Lua version should not
> result in a recompilation.

We cannot guarantee this.

--
Ricardo


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