I know you've probably already checked these but I'll ask anyway for the group:

Can the user ping your server?
Have you looked through the log files?
Are you using SMTP Auth and is it configured accordingly in the client?
Have the user reboot, this solves 9 out of 10 problems.

---------- Original Message ----------------------------------
From: "Vincent Toussaint" <[EMAIL PROTECTED]>
Reply-To: [EMAIL PROTECTED]
Date:  Tue, 13 Jan 2004 14:46:02 -0500

>One of my users can't send any mail with OE.  He's always getting this
>error :
> 
>The connection to the server has failed. Account: 'mail1', Server:
>'xxx.xxx.xxx.xxx', Protocol: SMTP, Port: 25, Secure(SSL): No, Socket
>Error: 10061, Error Number: 0x800CCC0E
> 
>I have look the MS Knoledge Base, the IpSwitch KB and the list archives
>without any results.  The user can send using the web interface.
> 
>Any chance this could be related to the Verisign certificat expiration
>of last week ?
> 
>We run Imail 8.05 with AV solution in a corporate environnement.  1
>domain with 110 users on Active Directory.
> 
>Vincent Toussaint
> 
>
>

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