Lyx and BibDesk connection

[Dr . Joachim K . Rennstich]

I am new user to Lyx and I have been working on a Mac (10.5) with  
TeXShop and BibDesk successfully so far. I just updated to the latest  
Mac install for TeX and gave Lyx another try in v1.6 and want to do  
the switch. Here's my problem - whenever I try to send something from  
BibDesk to Lyx, I get the following error msg:

Unable to open the LyX pipe at "/Users/jrennstich/Library/ 
Application Support/LyX-1.6/.lyxpipe.in" for writing.  You should  
quit LyX and possibly remove the pipe manually if this error  
persists.  The underlying system error code was 6 (Device not  
configured).


I saw the post here http://wiki.lyx.org/Mac/Environment about changing  
the .MacOSX/environment.plist but I am simply not able to find the  
relevant files: neither the .lyxpipe.in, nor ~/.MacOSX/ 
environment.plist.

Any help how to link Lyx and BibDesk successfully and help Lyx and  
BibDesk identify my .bib libraries would be greatly appreciated. I  
couldn't find that information in a search on here, my apologies, if  
this has been covered before :-( Needless to say, since I cannot find  
the lyxpipe.in nor the environment.plist, I am one of those sad Mac- 
users, who need a GUI and some guidance if that won't let me do the  
stuff I need to do... ;-)

Thx,
-Joachim