Fastmail says that Legacy Guest accounts do not have SMTP permission. Do you have a paid account, or a Legacy Guest account?
https://www.fastmail.fm/help/technical/servernamesandports.html I vaguely recall that is one reason why I stopped using fastmail. If you have an account for which Fastmail allows SMTP, make sure you have enabled SMTP on the fastmail end. The following page talks about how to use your ISP's SMTP server in conjuntion with fastmail, as an alternative, and also has a statement from Fastmail. http://www.emaildiscussions.com/showthread.php?t=66248 Eliana