Backing up large dbs with tar

[Van]

Greetings:

I have a 600M data file that never gets backed up.  The following error 
occurs in the cron job:

tar: /data/mysql/"my_db_name"/"my_large_table_name".MYI: file changed as we 
read it

Is there a way I can set this one table to read-only prior to the backup 
without affecting other db writes during this operation?

Thanks,
Van

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