"no route to host" error message

[Engin qwert]

Hello, I set my postfix server using a ready made shell script. The Mail server 
is working as excepted except the localhost it self. So the Mail Server can not 
send mail using Icedove, Telnet nor PHP' mail () function. When I run "mailq" 
command the error message is as shown below.--------------679D8120710      611 
Fri Jul 13 12:34:05  some_sender@some_domain.tld               (connect to 
mx2.hotmail.com[65.55.92.184]:25: No route to host)                             
            some_receip...@hotmail.com--------------Note: I changed the 
receipent and the sender addresses