tswmmeejsdad .:
> \\ snippet of postfix config
> 
> mynetworks = 127.0.0.0/8, 10.x.x.0/19
> smtpd_sender_restrictions = check_sender_access
> hash:/etc/postfix/access-sender reject
> 
> My questions is - Is there a way to get postfix to allow Outlook out of
> office replies 

Whitelist the Exchange server.

/etc/postfix/main.cf:
    smtpd_sender_restrictions = 
        check_client_access hash:/etc/postfix/access-client
        check_sender_access hash:/etc/postfix/access-sender 
        reject

/etc/postfix/access-client:
    # The Exchange server name or IP address.
    1.2.3.4     OK

You may also need to do this in smtpd_recipient_restrictions
(or smtpd_relay_restrictions, if applicable).

        Wietse

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