My sincere thanks, Viktor.

Removing the domain from $mydestination fixed the problem.
Testuser2's message was properly delivered to the mailbox on the MDA server.

-----Original Message-----
From: <[email protected]> on behalf of Viktor Dukhovni 
<[email protected]>
Reply-To: "[email protected]" <[email protected]>
Date: Friday, August 6, 2021 at 11:04
To: "[email protected]" <[email protected]>
Subject: Re: [EXTERNAL] Re: Inbound/Outbound Settings on a Postfix Relay-Only

    On Fri, Aug 06, 2021 at 12:33:22PM +0000, White, Daniel E. 
(GSFC-770.0)[NICS] wrote:


    From which we can conlude that you've listed the domain in
    "mydestination" (domains delivered to local accounts on the MTA host),
    which requires that the recipient "testuser2" be listed in /etc/passwd,
    or in the local aliases(5) table.

 
        Viktor.

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