On the page http://esw.w3.org/topic/HCLSIG_BioRDF_Subgroup/Tasks/URI_Best_Practices/Use_Cases I have written that an "ontology of resolvable resources" would be practical in some cases.
I have created such a small ontology, it can be downloaded / imported from http://neuroscientific.net/ont/resolvable.owl cheers, Matthias