Hi Andrea,

I remember you got the recommendation to try ELK on the Biohackathon mailing list. Is ELK not working for you? You might also want to give TrOWL a try if ELK is not working for you for some reason. Konclude might also be an option as it seems to outperform most other reasoners, but it does not have a Protege plugin (don't know if this matters to you). You can also have a look at the recent results of the OWL reasoner evaluation here:
http://vip.cs.man.ac.uk:8080/live.html

I have not worked with HPO yet, so those are just some general recommendations.

Best,
Matthias



Am 04.08.2014 13:53, schrieb Andrea Splendiani:
Hi all,

I have stumbled onto a problem for which I would like to hear from your experience.

In a project, I am using the Human Phenotype Ontology (http://www.human-phenotype-ontology.org/). For the sake of the project, I really only need the is_a structure of the ontology, but as an OWL version was existing, and as we have anyway an RDF framework to integrate data, I was thinking of using this version. The OWL version is not a simple representation of the is_a structure, as it is including axioms to map phenotypes to, from a quick inspection, anatomical parts and "qualities".

Now, as with any ontology, I was at first trying to classify it. This is an ontology (with imports) of around 20k classes (<200k axioms, ~60k logical axioms). It is big, but not huge.
I simply cannot classify it in any reasonable time.
I have tried a variety of reasoners and, in my longest wait, I have waited for days but we are under 1%).

Does anybody have experience in classifying it ?

If classification is unfeasible, than which use cases does the OWL representation cater to?

best,
Andrea Splendiani


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