While we are at listing our favorite R GUIs, I'll throw RKWard into the ring: http://rkward.sf.net .
I assume you are aware of the list of R GUI projects at http://rwiki.sciviews.org/doku.php?id=guis:projects ? Also, the Journal of Statistical Software is planning a special issue on R GUI (scheduled to be published some time this year; http://www.jstatsoft.org/). You may want to look out for that. Regards Thomas
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