[ccp4bb] Permanent Crystallographer needed at Colorado State
Dear Colleagues: I’d like to advertise a new PhD-level, permanent staff scientist position available at Colorado State University, located in Fort Collins, CO. Fort Collins is a wonderful place to live, located at the foothills of the Rocky Mountains with over 300 days of sunshine a year. We are looking for someone to manage our diverse X-ray laboratory and serve as a crystallographer for the laboratory. This is someone that I have traditionally worked quite closely with. The full job description is here: https://jobs.colostate.edu/postings/131812 We are explicitly looking for someone with experience in single crystal X-ray structure solution and single crystal diffractometer operation and maintenance. We would also prefer applicant with experience with powder diffraction, thin-film diffraction, and/or small-angle X-ray scattering. The salary range is listed at $60,000-$75,000 USD. The position is open to international and domestic applicants. To ensure full consideration, applications must be received by September 8 2023. Thank you, Jamie James R. Neilson, PhD Associate Professor Department of Chemistry Colorado State University neilsonlab.colostate.edu phone: 970 491 2958 he/him/his To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] postdoctoral positions available
Dear Colleagues, A postdoctoral position is immediately available for a highly motivated individual interested in elucidating molecular mechanisms of ubiquitin signaling and DNA repair. Research is focused on the enzymatic machinery responsible for protein ubiquitination and large protein complexes involved in regulating DNA repair and immunity. These issues will be addressed using a multidisciplinary approach that includes cryo-EM and X-ray crystallography, complemented with biochemical/biophysical techniques and cell-based assays. Successful candidates will join the vibrant scientific community at UT Health San Antonio and enjoy abundant access to state-of-the-art cryo-EM instrumentation including a Glacios TEM equipped with a Falcon 4 direct electron detector and Selectris Imaging Filter that are the centerpiece of our brand new cryo-EM facility. Access to outstanding X-ray crystallography and NMR resources are also available. Candidates should hold a recently obtained PhD in biochemistry, chemistry, or related subject. Demonstrated expertise in cryo-EM is highly desirable, though individuals with expertise in protein chemistry, and/or the biochemical analysis of protein ubiquitination and/or DNA repair will also be considered. Experience with protein expression in insect and mammalian cells is a plus. Recent publications highlighting our research interests: *Structural insights into BCDX2 complex function in homologous recombination [https://www.nature.com/articles/s41586-023-06219-w] *Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer [https://www.nature.com/articles/s41467-023-39780-z] *Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6 [https://www.nature.com/articles/s41467-022-32613-5] *Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design [https://www.science.org/doi/10.1126/sciadv.abd4596] Interested candidates should e-mail a cover letter, CV, and the names of three references to: ols...@uthscsa.edu. Best, -Shaun To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] Assistant Professor Position in Biophysics/Structural Biology. Rice University@Houston
Dear All, Assistant Professor in BioSciences: The Department of BioSciences at Rice University (https://biosciences.rice.edu/) invites applications for three tenure-track, assistant professor positions to begin July 1, 2024. Rice University is a private research university located in Houston, Texas and is a member of the Texas Medical Center. Research in the BioSciences Department at Rice University leverages quantitative approaches to study biological systems using both bottom-up and top-down experimental procedures. We particularly welcome applications in neuroscience, biophysical and structural biology, and synthetic biology, including scholars who leverage computational biology approaches in each of these areas. We seek applicants with research programs that will complement the existing research in the BioSciences department. The successful candidate will lead a dynamic, innovative, and independent research program supported by external funding and will teach courses at the graduate and undergraduate levels. Rice University seeks to expand access, diversity, and inclusion. These aims have long been a part of the university’s strategic designs (see, Vision for the Second Century), and they will continue moving forward. In this spirit, we welcome applicants who have the skills, knowledge, and commitment to mentor all members of our diverse student population, including applicants of all genders, members of historically underrepresented groups, and others who exemplify diverse cultural experiences. Candidates must have a PhD or equivalent degree in a biological science or a relevant field of natural science or engineering (or have completed the requirements for a PhD by July 1, 2024). To apply, please submit the following materials online at http://apply.interfolio.com/130021: (1) cover letter; (2) curriculum vitae; (3) research statement (3 pages max); (4) statement of teaching philosophy (2 pages max); (5) diversity statement (2 pages max); and (6) contact information for three references. Application review will commence October 31, 2023 and will continue until the position is filled. For additional information, please contact the search chair, Dr. Daniel Wagner: dswag...@rice.edu. Best Yang To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
Re: [ccp4bb] An unknown but strong positive electron density in my crystal
THank you - it is on a two fold axis you said? That means it could be a sort of average of a molecule.. Eleanor PS Any anomalous peaks? On Mon, 14 Aug 2023 at 10:32, Yue Li wrote: > Hi everyone, > > Thank you for your replies. I have uploaded the figures to a website. The > link is here: > > yueliblog.webador.co.uk > > > Best wishes, > Yue > > > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 > > This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a > mailing list hosted by www.jiscmail.ac.uk, terms & conditions are > available at https://www.jiscmail.ac.uk/policyandsecurity/ > To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
Re: [ccp4bb] An unknown but strong positive electron density in my crystal
Hi everyone, Thank you for your replies. I have uploaded the figures to a website. The link is here: yueliblog.webador.co.uk Best wishes, Yue To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/