[Fis] New Discussion Session
Dear FIS Colleagues, We are preparing a new discussion session. Our invitee will be my colleague *Alberto Jiménez Schuhmacher*. He is a molecular biology researcher of our Institute (IIS Aragon) who has recently established his own lab. (So, he is relatively young!) But he has a very brilliant record of research achievements, mostly related to cancer physiology and detection and "virtual biopsies". In what extent are we heading towards a new research paradigm of *DATAISM, as the end of classical hypothesis-driven research and the beginning of data-correlation-driven research?* In a few days he will post his kickoff text. Best wishes to all, Raquel -- ----- Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - --- El software de antivirus Avast ha analizado este correo electrónico en busca de virus. https://www.avast.com/antivirus ___ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis
[Fis] [Informational Bookkeeping] Jerry LR Chandler
Mensaje original Asunto: Re: [Fis] Informational Bookkeeping Fecha: Mon, 8 Sep 2014 09:51:28 -0400 De: Jerry LR Chandler jerry_lr_chand...@me.com A: Raquel del Moral rdelmoral.i...@aragon.es Raquel: The bookkeeping of cells and all other living creatures is in terms of atomic numbers. The exactness of this bookkeeping is ensured by the physical laws of the conservation of mass and the conservation of electricity. The method of bookkeeping is by the principles of relatonomics (a term coined for the purpose of bookkeeping by the electrical content of the atomic numbers.) Cheers Jerry On Sep 8, 2014, at 8:11 AM, Raquel del Moralrdelmoral.i...@aragon.es wrote: Dear Pedro, The concept of bookkeeping looks very interesting for biology, however, I can't see clearly how to apply it below the level of nervous systems. Counting maybe found in most biomolecules, but really registering in a book keeping manner is possible in the lower levels? e.g. unicellulars. Do you think that they modify their behaviour after checking their own bookkeeping registers? Just this brief comment! Best, Raquel El 05/09/2014 14:14, Pedro Marijuan escribió: Dear FIS colleagues, A very interesting comment by Bob about energy as a bookkeeping device in the other discussion track motivates these rough reflections. Actually, within the culture of mechanics (following Frank Wilczek) energy appears as the more reliable concept, beyond its cousins force and mass. Mechanics, like most scientific theories, finally is but a method to count upon variable aspects of simplified phenomena and provide inter-subjective objectivity(?). Numbers are due to our mental counting operations; and concepts, formulas and theories become bookkeeping devices to obtain more complex counting that dovetail with more complex phenomena. That our mental counting dovetails with nature's pretended counting is what the experimental side of science tries to establish. It becomes of great merit that energy constructs such as those mentioned by Bob do their bookkeeping accurately, in spite of their intrinsic limitations. My concern with the views expressed in the other track is that informational bookkeeping appears to be rather different from the mechanical physical bookkeeping or counting. There are new aspects not covered by the extensive and inflexible mechanical-dynamic counting, and which are essential to the new informational organizations we are discovering --and practicing around-- and to the new worldview that presumably we should search and promote. Is there bookkeeping in life? Do molecules count? Do bacteria or unicellulars bookkeep--and organisms? And complex brains? And individuals? And social groups? And companies and markets? And cities, regions and countries? Admittedly it is a potpourri; but yes, there are some clear instances where quite explicit a bookkeeping is maintained. It may be about signaling flows, about self production stuff flows, or about their inextricable mixing--involving whatever aspects. But these bookkeepings are made with attentional flexibility and different closure procedures that allow for new forms of compositional hierarchy (informational) not found in the mechanical. They are adaptive, they recognize, they are productively engaged in life cycles where the meaning is generated, they co-create new existential realms... In our own societies, the exaggerated importance of new informational devices (historically: numbers, alphabets, books, calculi, computers, etc.) derives from their facilitation and acceleration of all the enormous bookkeeping activities that subtend the social complexity around. Who knows, focusing on varieties of bookkeeping might be quite productive! best ---Pedro *Pedro C. Marijuán Fernández* Dirección de Investigación Instituto Aragonés de Ciencias de la Salud (IACS) Instituto de Investigación Sanitaria Aragón (IIS Aragón) Centro de Investigación Biomédica de Aragón (CIBA) Avda. San Juan Bosco, 13, planta 1 50009 Zaragoza Tfno. +34 976 71 4857 email. dirinvestigacion.i...@aragon.es mailto:dirinvestigacion.i...@aragon.es www.iacs.aragon.es ___ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis . -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis . ___ Fis
Re: [Fis] Informational Bookkeeping
Dear Pedro, The concept of bookkeeping looks very interesting for biology, however, I can't see clearly how to apply it below the level of nervous systems. Counting maybe found in most biomolecules, but really registering in a book keeping manner is possible in the lower levels? e.g. unicellulars. Do you think that they modify their behaviour after checking their own bookkeeping registers? Just this brief comment! Best, Raquel El 05/09/2014 14:14, Pedro Marijuan escribió: Dear FIS colleagues, A very interesting comment by Bob about energy as a bookkeeping device in the other discussion track motivates these rough reflections. Actually, within the culture of mechanics (following Frank Wilczek) energy appears as the more reliable concept, beyond its cousins force and mass. Mechanics, like most scientific theories, finally is but a method to count upon variable aspects of simplified phenomena and provide inter-subjective objectivity(?). Numbers are due to our mental counting operations; and concepts, formulas and theories become bookkeeping devices to obtain more complex counting that dovetail with more complex phenomena. That our mental counting dovetails with nature's pretended counting is what the experimental side of science tries to establish. It becomes of great merit that energy constructs such as those mentioned by Bob do their bookkeeping accurately, in spite of their intrinsic limitations. My concern with the views expressed in the other track is that informational bookkeeping appears to be rather different from the mechanical physical bookkeeping or counting. There are new aspects not covered by the extensive and inflexible mechanical-dynamic counting, and which are essential to the new informational organizations we are discovering --and practicing around-- and to the new worldview that presumably we should search and promote. Is there bookkeeping in life? Do molecules count? Do bacteria or unicellulars bookkeep--and organisms? And complex brains? And individuals? And social groups? And companies and markets? And cities, regions and countries? Admittedly it is a potpourri; but yes, there are some clear instances where quite explicit a bookkeeping is maintained. It may be about signaling flows, about self production stuff flows, or about their inextricable mixing--involving whatever aspects. But these bookkeepings are made with attentional flexibility and different closure procedures that allow for new forms of compositional hierarchy (informational) not found in the mechanical. They are adaptive, they recognize, they are productively engaged in life cycles where the meaning is generated, they co-create new existential realms... In our own societies, the exaggerated importance of new informational devices (historically: numbers, alphabets, books, calculi, computers, etc.) derives from their facilitation and acceleration of all the enormous bookkeeping activities that subtend the social complexity around. Who knows, focusing on varieties of bookkeeping might be quite productive! best ---Pedro *Pedro C. Marijuán Fernández* Dirección de Investigación Instituto Aragonés de Ciencias de la Salud (IACS) Instituto de Investigación Sanitaria Aragón (IIS Aragón) Centro de Investigación Biomédica de Aragón (CIBA) Avda. San Juan Bosco, 13, planta 1 50009 Zaragoza Tfno. +34 976 71 4857 email. dirinvestigacion.i...@aragon.es mailto:dirinvestigacion.i...@aragon.es www.iacs.aragon.es ___ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis . -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis
[Fis] social exchanges
Dear FIS colleagues, Thanks for the comments received (basically Pedro and Bi Lin!). I am not much conversant today about cellular or bacterial communication (sorry Bruno...), as I try to discuss on person to person communication. About the empirical data of my research, of interest for Bi Lin, we published a poster in AAAS Meeting 2012. I will upload that poster and some new data once the FIS website is refurbished. The basic data are not very different from a paper in Science (Are women really more talkative than men? Science 2007, vol. 317, pp:82), although we are looking from a wider angle, concretely the correlation with Mental Health. The gender differences are very intriguing! For the new comers in the list, there is an archive with all the messages exchanged: https://webmail.unizar.es/pipermail/fis/ Interested parties may look for the current discussion session, which started on 27/09/2013. Best, Raquel El 12/11/2013 13:31, Bruno Marchal escribió: Dear Bi, On 12 Nov 2013, at 09:55, bilin1001 wrote: Dear Raquel, I am also a PhD student, in Information Philosophy. My Thesis deals with Mutual Meaning Space in social exchanges (interpersonal communication). I am very interested in your work on the necessity of conversation: do you have empirical data about that? Sex, which can be seen as molecular conversation, is an empirical data for the necessity of conversation, taken as exchange of information (DNA). Bacteria do it, either directly, or through viruses (the GSM of the bacterium). Its main role is in the sped up of creating theories (the genome), and being able to refute them as much quickly (selection). Is there a first person notion associated with it? Probably. Hard to know. Best wishes, Bruno http://iridia.ulb.ac.be/~marchal/ ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
[Fis] Discussion Recap.
Hi to everyone, Sorry for my tardiness (life within a PhD is not very easy!) First, I am happy that every body has agreed on the conceptual chain genotype-phenotype-sociotype. For me that's important, as it is one of the foundations of my own work and the research project associated. I return to John Collier’s comments on sets of behaviors (praxotype) and cognitive capabilities (cognotype). It calls my attention that the cognotype is defined as a software: something configurable and extendable. This point makes me consider: has our cognition limits? From my point of view, the brain needs to be stimulated in order to be minimally functional, to feel good. Brain stimulation is needed to fix, maintain and strengthen the whole knowledge architecture, particularly in the social domain. Is there also an upper limit in this cognitive stimulation, or do we have unlimited processing capabilities? Seemingly, over-stimulation is only possible for a while, after which you lose the mental resistance and exhaustion ensues. In general, over-stimulation becomes negative and produces stress (e.g. learning in babies). Therefore, I believe that effective processing capacity does move within certain limits or thresholds. Following the need to distinguish levels, I see our cognitive skills set as the essential element (micro). The behavior of the individual, the adopted roles, and the multiple relational situations are social phenomena studied by social psychology. Ok, but in order to understand the emerging macro-variables of the social structure, one must always take into account the whole cognitive capabilities of the individual. Hence I consider they are closely related levels. Although they may not follow the same laws, I think that they converge in the fact of moving within approximate thresholds, outside of which the system effectiveness is lost. To make it clearer, in the extent to which they are effective, we could explore quantitatively some of these individual/social thresholds. And that's the goal of my PhD Thesis on the sociotype, to try to capture a few of them. How many relationships? How much talk? Thanks to all for the useful comments! Raquel -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
Re: [Fis] THE SOCIOTYPE: From R. Zimmerman
Dear Krassimir, Stan, and Rainer, thank you very much for youy comments. In a few days I will try to respond, but for today, what about responding to a few basic sociotype questions? How many nuclear family relationships do you have? And how many close friends? and extended family? And finally, how many social acquaintances? Can you quantify how much time do you talk daily (on average)? Can you separate the talking time for the above four categories? I know this is pretty difficult (people have a lot of troubles on our test) but I would like to find some fis-volunteers... You can also respond me offline Good weekend! Raquel El 09/10/2013 11:15, Pedro C. Marijuan escribió: Message from Rainer Zimmermann Dear Raquel, may I just point out that your conception which I find quite promising, should be modified somewhat as to the symmetry between micro- and macrolevels(a point that is actually very important in order to introduce any concepts of emergence into this): Hence, if visualizing the sociality of human beingsas a kind of biological selection criterium that emerged some time during the hominization period and had to prove its evolutionary advantages by becoming a dominating paradigm, then sociality would have a micro-component (psychotype) which is the formal equivalent of the biological genotype, and a macro-component (sociotype) which is the formal equivalent of the biological phenotype. The advantage of defining two of these levels is twofold: first, it is more correct, because evolution on the one level does not necessarily entail the same evolution on the other, second, social groups consist of individuals which are to the social field generated by that group a singularity which is one source of this field at the same time. Hence, the agglomeration of individuals in groups cannot be described by the same language that is applied to describe the individuals. One is the macro-level (sociology), the other is the micro-level (psychology).The first is emergent with respect to the latter. Best, Rainer ___ fis mailing list ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
Re: [Fis] FIS new course
Dear FISers, We have been working in a couple of new ideas for the list. As Pedro has advanced you, for this new course we have planned two different kind of discussions, the thematic regular session (both junior and senior), and a new modality consisting in short discussions about interesting papers (we will arrange in the refurbished fis webpages a new platform to upload the papers). In relation to this, let me introduce you our new web master, David Sierra. We two will try to develop progressively the new changes, including the suggestions I have already received (Thanks!). About the sociotype session, in a few weeks I will have finished the opening text. I hope we will have an exciting discussion! All the best, Raquel El 10/09/2013 18:05, Pedro C. Marijuan escribió: Dear FISers, We start a new course, hopefully retaking our exciting exchanges and discussions. Next days Raquel will send all of us a few detailed proposals. Besides our chaired discussion sessions, we are also trying to develop a new type of sessions, shorter ones, for instance around interesting publications --sort of a Journal Club. We have planned a couple of tentative regular sessions (one around the sociotype, and another about Noumena... well next days we will send more info. Herein I am adding below an abstract we have just published about eukaryotic intelligence. Maybe we can discuss about it until the next session starts. best wishes to all ---Pedro -- BioSystems 114 (2013) 8-- 24 *On eukaryotic intelligence: Signaling system's guidance in the evolution of multicellular organization* Pedro C. Marijuán?, Raquel del Moral, Jorge Navarro Bioinformation and Systems Biology Group, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza 50009, Spain Communication with the environment is an essential characteristic of the living cell, even more when considering the origins and evolution of multicellularity. A number of changes and tinkering inventions were necessary in the evolutionary transition between prokaryotic and eukaryotic cells, which finally made possible the appearance of genuine multicellular organisms. In the study of this process, however, the transformations experimented by signaling systems themselves have been rarely object of analysis, obscured by other more conspicuous biological traits: incorporation of mitochondria, segregated nucleus, introns/exons, flagellum, membrane systems, etc. Herein a discussion of the main avenues of change from prokaryotic to eukaryotic signaling systems and a review of the signaling resources and strategies underlying multicellularity will be attempted. In the expansion of prokaryotic signaling systems, four main systemic resources were incorporated: molecular tools for detection of solutes, molecular tools for detection of solvent (Donnan effect), the apparatuses of cell-cycle control, and the combined system endocytosis/cytoskeleton. The multiple kinds of enlarged, mixed pathways that emerged made possible the eukaryotic revolution in morphological and physiological complexity. The massive incorporation of processing resources of electro-molecular nature, derived from the osmotic tools counteracting the Donnan effect, made also possible the organization of a computational tissue with huge information processing capabilities: the nervous system. In the central nervous systems of vertebrates, and particularly in humans, neurons have achieved both the highest level of molecular-signaling complexity and the highest degree of information-processing adaptability. Theoretically, it can be argued that there has been an accelerated pace of evolutionary change in eukaryotic signaling systems, beyond the other general novelties introduced by eukaryotic cells in their handling of DNA processes. Under signaling system's guidance, the whole processes of transcription, alternative splicing, mobile elements, and other elements of domain recombination have become closely intertwined and have propelled the differentiation capabilities of multicellular tissues and morphologies. An amazing variety of signaling and self-construction strategies have emerged out from the basic eukaryotic design of multicellular complexity, in millions and millions of new species evolved. This design can also be seen abstractly as a new kind of quasi-universal problem-solving 'engine' implemented at the biomolecular scale---providing the fundamentals of eukaryotic 'intelligence'. Analyzing in depth the problem-solving intelligence of eukaryotic cells would help to establish an integrative panorama of their information processing organization, and of their capability to handle the morphological and physiological complexity associated. Whether an informational updating of the venerable cell theory is feasible or not, becomes, at the time being -- right in the middle of the massive data deluge/revolution from omic disciplines
[Fis] Fwd: Re: IT pitfalls? the other side of new infotechnologies
Dear FISers, herein a message from Krassimir; the attachment he mentions can be find in the journal ITHEA. --Raquel Mensaje original Asunto: Re: [Fis] IT pitfalls? the other side of new infotechnologies Fecha: Sat, 22 Jun 2013 00:40:32 +0300 De: Krassimir Markov mar...@foibg.com Responder-a:: Krassimir Markov mar...@foibg.com Organización: FOI; ITHEA A: Joseph Brenner joe.bren...@bluewin.ch, Raquel del Moral rdelmoral.i...@aragon.es Dear Raquel and Josef, The other side of new info-technologies is quite dark ! Because of : The problems which concern information and societies may be separated in two main parts: - information in business, and - business with information. Both are based on modern IT technologies. Business here is in its broadly meaning – all human activities (private and social). We are Information subjects (INFOS-es) and our live tightly depends of information interaction and exchange. And this cause the business with information... Business with information is provided at the: - information marked, and - knowledge market, which is subdivision if the information market. As at all other markets, here the main goal is not human prosperity but profit and monopolies. Not clear understanding of the lows of information markets and, especially – of knowledge markets, is a great problem of all of us. Problems you have pointed are closely connected to this, I think. Please find attached the first issue of Jubilee 20th volume of the International Journal “Information Theories and Applications”. Its first two papers discuss some similar problems. Friendly regards Krassimir PS: I do not send this letter to FISers because of the attachment. *From:* Joseph Brenner mailto:joe.bren...@bluewin.ch *Sent:* Friday, June 21, 2013 3:53 PM *To:* Raquel del Moral mailto:rdelmoral.i...@aragon.es ; fis mailto:fis@listas.unizar.es *Subject:* Re: [Fis] IT pitfalls? the other side of new infotechnologies Dear Raquel, You wrote: The whole effect of ITs on time allocation, learning, cognitive and emotional development, social bonding, and mental health has scarcely been researched… ...the “tunnel vision” promoted by information techno-utopians and propagandists I think it is absolutely essential to call attention of people to the reality of these aspects of ITs as they are actually used and introduce some balance in the debate. One approach I suggest that may be useful in this strategy is to emphasize the qualitative, functional features of information itself, information-as-operator (Mark Burgin), information-as-process, /etc. / Best wishes, Joseph - Original Message - *From:* Raquel del Moral mailto:rdelmoral.i...@aragon.es *To:* fis mailto:fis@listas.unizar.es *Sent:* Friday, June 21, 2013 2:12 PM *Subject:* [Fis] IT pitfalls? the other side of new infotechnologies Dear FISers, I would like to exchange views about one of the aspects of my work (although is not the central theme of my thesis, and I will delay the post of the “sociotype” subject after summer time). We are contemplating the adverse consequences of the technology use. It relates to the discussions had in Milton Keynes conference, basically between Pedro and Liesbet and Luciano about the social pitfalls of contemporary information technologies. (I think that the records of these sessions can be found in the web) What we are considering is that the Information Technology grandeur (the brilliant aspects are publicized everywhere!) is accompanied by a growing sense of information saturation and impoverished socialization. Loneliness and depression indicators are in the raising, and happiness indicators are in the declining. The whole effect of ITs on time allocation, learning, cognitive and emotional development, social bonding, and mental health have been scarcely searched… Clearly, other unwanted effects more distant from mental health, such as the energetic burden, the pollution, the waste, the accelerated obsolescence, and the pilfering of valuable (e irreplaceable) mineral resources are seemingly beyond the “tunnel vision” promoted by information techno-utopians and propagandists. The micro-rationality of individual decisions in the market-context may conduce in the aggregate to utter social irrationality. What do you think about this controversy? Best, Raquel -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Centro de Investigación Biomédica de Aragón (CIBA) Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 e-mail.rdelmoral.i...@aragon.es
[Fis] IT pitfalls? the other side of new infotechnologies
Dear FISers, I would like to exchange views about one of the aspects of my work (although is not the central theme of my thesis, and I will delay the post of the sociotype subject after summer time). We are contemplating the adverse consequences of the technology use. It relates to the discussions had in Milton Keynes conference, basically between Pedro and Liesbet and Luciano about the social pitfalls of contemporary information technologies. (I think that the records of these sessions can be found in the web) What we are considering is that the Information Technology grandeur (the brilliant aspects are publicized everywhere!) is accompanied by a growing sense of information saturation and impoverished socialization. Loneliness and depression indicators are in the raising, and happiness indicators are in the declining. The whole ITs effects on time allocation, learning, cognitive and emotional development, social bonding, and mental health have been scarcely searched... Clearly, other unwanted effects more distant from mental health, such as the energetic burden, the pollution, the waste, the accelerated obsolescence, and the pilfering of valuable (e irreplaceable) mineral resources are seemingly beyond the tunnel vision promoted by information techno-utopians and propagandists. The micro-rationality of individual decisions in the market-context may conduce in the aggregate to utter social irrationality. What do you think about this controversy? Best, Raquel -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Centro de Investigación Biomédica de Aragón (CIBA) Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 E-mail. rdelmoral.i...@aragon.es - ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
[Fis] FIS Secretariat
Dear FISers, I am Raquel del Moral and, as Pedro has told you, I am going to cooperate with him to administer the FIS list. So I hope to develop properly this new task --at least I'll do my best! I am happy to participate actively in this exciting project, and I will try to bring some new ideas about the list discussions and the fis web pages. But of course, to maintain alive the FIS forums the most important factor is receiving your ideas and contributions. Please, feel free to contact me and to propose whatever items or suggestions(preferably through personal mails, off-list). Best greetings, Raquel -- - Raquel del Moral Grupo de Bioinformacion / Bioinformation Group Instituto Aragonés de Ciencias de la Salud Centro de Investigación Biomédica de Aragón (CIBA) Avda. San Juan Bosco 13, 50009 Zaragoza Tfno. +34 976 71 44 76 e-mail.rdelmoral.i...@aragon.es ** You may have a glance on the bioinformation group at: https://sites.google.com/site/pedrocmarijuan/archivos - ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
Re: [Fis] Beijing FIS Group
Hi! thank you Xueshan for the question: Are there any difference between transmitter in Neuroscience and hormone in Endocrinology from the viewpoint of information transmission and communication ? I can only give a few hints, as otherwise the message would be awfully long: In the reception aspect there are clear differences: neurotransmitters information enters into the cell by means of the activation of ligand-gated channels (also throughout G proteins pathways) and it is a very fast process, often in miliseconds; while hormones (e.g. steroids) affect very slow pathways usually of intracellular receptors with only one-component. But this difference is often blurred as hormones may occupy G proteins pathways too. As for the emission aspect, hormones are often endocrine (holistic impact via circulatory system) and paracrine (regionally secreted) while neurotransmitter are terribly localized at the level of the synapse. Again things get complicated, as neuropeptides for instance may be working in both ways; endocrine-paracrine as neuromodulators, and locally as neurotransmitters (even mixed also at the level of their reception pathways!!). Better if we dont speak about transportation ;-) !! Was it useful at all? A good reference can be found in Kandel et al. Mc Graw-Hill 2000 (a very tough book!) Best regards, Raquel -- ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
Re: [Fis] Beijing FIS Group
Hi! We are Jorge Navarro and Raquel del Moral, we both work with Pedro in Systems Biology and Neuroscience (we are experimentalist and theoretical too, very close to some of you). Congratulations for your great group it looks very impressive-- and welcome to the FIS. We expect we will exchange ideas and cooperate with you in not so long time.:) Its always nice to share knowledge about science! -- ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
Re: [Fis] fis events--cognits
Hi! I'm new in the list, from the field of neurobiology. I've been googling about the cognit stuff but apart from Fuster book, the results have been very disappointing. Could anyone in the list, please, indicate me further references? Thank you very much!! Raquel Pedro C. Marijuan escribi: Dear FIS colleagues, Real conferences are unique occasions where ideas and projects may fructify far more easily than just via electronic means. There might be some fis-related events next year, among them the Symmetry conference announced days ago. Well, in the last conference arranged in Leon (Spain) about the Information concept and Information theories, one of the outcomes was arranging a small group to advance in the neuroscientific, cognitive and logical aspects associated to the "cognit" approach --interested parties will remember it was also discussed months ago in our list. A prestigious neuro-imaging researcher of Madrid (Tomas Ortiz), myself and a few other Spanish colleagues from logics and linguistics are in the group. Tomas has just joined our discussion list... It is a difficult task, and we will welcome any cooperation or involvement from FIS colleagues, either in the small group or openly in the list. Cognits, as was originally "coined" by neuroscientist J. Fuster, are quite intriguing constructs, and may imply a radically new approach to categories / concepts regarding human communication. best Pedro Pedro C. Marijun Grupo de Bioinformacin Instituto Aragons de Ciencias de la Salud Avda. Gmez Laguna, 25, Pl. 11 50.009 Zaragoza. Espaa Telf: 34 976 71 3526 ( 6818) Fax: 34 976 71 5554 [EMAIL PROTECTED] ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis -- ___ fis mailing list fis@listas.unizar.es https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis
