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Hi! thank you Xueshan for the question: I can only give a few hints, as otherwise the message would be awfully long:Are there any difference between transmitter in Neuroscience and hormone in Endocrinology from the viewpoint of information transmission and communication ? In the reception aspect there are clear differences: neurotransmitters information enters into the cell by means of the activation of ligand-gated channels (also throughout G proteins pathways) and it is a very fast process, often in miliseconds; while hormones (e.g. steroids) affect very slow pathways usually of intracellular receptors with only one-component. But this difference is often blurred as hormones may occupy G proteins pathways too. As for the emission aspect, hormones are often endocrine (holistic impact via circulatory system) and paracrine (regionally secreted) while neurotransmitter are terribly localized at the level of the synapse. Again things get complicated, as neuropeptides for instance may be working in both ways; endocrine-paracrine as neuromodulators, and locally as neurotransmitters (even mixed also at the level of their reception pathways!!). Better if we don´t speak about transportation ;-) !! Was it useful at all? A good reference can be found in Kandel et al. Mc Graw-Hill 2000 (a very tough book!) Best regards, Raquel --  |
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