[Freesurfer] aseg2feat for PPI seeds for FSL

2011-09-28 Thread Michelle Umali
Hi Freesurfers,
I want to do a PPI in FSL FEAT using the V1 left and righ found
generated in recon-all as seeds using:

I know for each subject I have to get a timecourse for my seeds
fslmeants -i filtered_func.nii.gz -o my_timecourse.txt -m V1_mask.nii.gz

For each subject, I've run reg-feat2anat on my FEAT data from each of 4 runs.

I have 2 questions:
1) Does it matter which run's FEAT  I use for aseg2feat --feat featdir
--aseg aparc+aseg to generate the binary masks for my seeds?

2) Does fslmeants need a special registered filtered_func.nii.gz from
a cross-run GFEAT? If so, how do you specify it for this and then for
actual PPI analysis in fsl?

Thanks.
Michelle
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[Freesurfer] correction

2011-09-28 Thread Oertel, Viola
Dear Freesurfers, 
could you please give me detailed information about the Bonferroni or 
clusterwise correction we can do in Freesurfer? How much iterations? Is that 
cluster- oder voxelwise? Is there anywhere a detailed description about the 
correction options?
Best regards, 
Viola
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[Freesurfer] analysis.cfg not generated by mkanalysis-sess

2011-09-28 Thread Po-Jang (Brown) Hsieh
Dear all,

I ran mkanalysis-sess (mkanalysis-sess -analysis junk -TR 2 -paradigm
para01.para -event-related -funcstem fmc -nconditions 3 -runlistfile
runlist_odd -fsd bold -fir 10 30 -native) but it did't not generate
analysis.cfg. The only file I can see after running this is analysis.info.

When I ran mkanalysis-sess.new, both analysis-info and analysis.cfg are
generated as fine. Could any one know how to solve this problem?

ps. I'm running freesurfer5.1.0 on Mac OS X 10.6.8 (the mkanalysis-sess.new
is a copy from freesurfer4.5.0).

Thanks!
Brown
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[Freesurfer] Fwd: Talairach transformation

2011-09-28 Thread Maria Felber
Dear Ms. Kakunoori,

sorry to bother you again, but as I did not get a reply to my last message to 
everyone so far troubled with my question, I am trying here for a second time.
It is indeed the case, that all my data were scanned with a 3T. And if that is 
indeed the problem Dr. Snyder figured out, then what can I do about it? Or is 
anyone already working on this problem? I can hardly imagine I am the only one 
recording with a 3T instead of a 1.5T.
Yours sincerely,
Maria Felber

- Forwarded Message -
From: Maria Felber fel...@cbs.mpg.de
To: Avi Snyder a...@npg.wustl.edu
Cc: Sita Kakunoori\, fel...@cbs.mpg.de, \Avi Snyder\ a...@npg.wustl.edu, 
Bruce Fischl s...@nmr.mgh.harvard.edu, freesurfer@nmr.mgh.harvard.edu
Sent: Thursday, September 15, 2011 10:46:55 AM
Subject: Re: [Freesurfer]  Talairach transformation

Dear all,

indeed all my T1-scans were recorded with a 3T scanner. So what can I do about 
it or do you have something in progress which would fix this problem anytime 
soon?
Thanks,
Maria

- Original Message -
From: Avi Snyder a...@npg.wustl.edu
To: Sita Kakunoori s...@nmr.mgh.harvard.edu, fel...@cbs.mpg.de, Avi 
Snyder a...@npg.wustl.edu
Cc: Bruce Fischl fis...@nmr.mgh.harvard.edu
Sent: Tuesday, September 13, 2011 11:03:28 PM
Subject: Re: [Freesurfer]  Talairach transformation

Hi Sita,

Wrong-stretch (e.g., too fat or too thin) MP-RAGE atlas transforms are
expected if the contrast properties of the sample image are far from those
of the target. This condition can easily occur if the target is based on
1.5T data and the sample is acquired at 3T. (3T but not 1.5T T1W images
tend to be relatively bright in the center of the head.) Gd++ contrasted
MP-RAGE scans routinely do not produce decent atlas transforms unless
special measures are taken. A FreeSurfer fix for this problem is
theoretically feasible.

Avi
---
On 9/13/11 2:26 PM, Sita Kakunoori s...@nmr.mgh.harvard.edu wrote:

I might have seen this in a dataset. I am cc'ing Dr.Avi Anyder on this
e-mail.
Hi Dr.Snyder, Not sure if you remember but we saw something similar in a
dataset here at the center where the talairach was much smaller than the
orig.mgz volume and you created a new talairach template to be used with
that dataset. I just wondered if this issue is similar to that.

Thanks much,
Sita.
-- Forwarded message --
Date: Tue, 13 Sep 2011 16:27:17 +0200 (CEST)
From: Maria Felber fel...@cbs.mpg.de
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer]  Talairach transformation

Hi Bruce,

so we are back at the beginning. After I ran recon-all -all, I did
exactly that and checked the xform using tkregister2. And here I always
see that my talairach volume (the transform) is always smaller, which can
be very well seen as the orig surfaces of the subjects are always a
little outside the brain and reach well into the skull areas. Of course I
can make the adjustments as descriped in the short instructions. But this
also means I ran the recon-all precess anew for another 30 h per subject.
And that is the reason, why I asked if this is normal that the tailarach
transform is a) always smaller than the original brain, and b) if I can
make any adjustments to prevent that from happening and thus saving
another 30h per subject.
In short: How acurate hat the talairach.xfm has to be and is it possible
to change some parameters to make this transformation a little more
accurate while running the recon-all process only once?
Best,
Maria


- Original Message -
From: Bruce Fischl fis...@nmr.mgh.harvard.edu
To: Maria Felber fel...@cbs.mpg.de
Cc: freesurfer@nmr.mgh.harvard.edu
Sent: Tuesday, September 13, 2011 4:07:55 PM
Subject: Re: [Freesurfer] Talairach transformation

Hi Maria

you can use tkregister2 to check the accuracy of the talairach.xfm
transform (xform for short), and correct it if you want.

cheers
Bruce
On Tue, 13 Sep 2011, Maria Felber wrote:

 Hi Bruce,

 thanks for the first response. I tried to find some information on the
webpage about xform, but failed. So what is xform standing for and
where/how can I check it?
 As in the later processing stages I want to do localization and
DCM-Modeling with my data, I guess the correct talairach coords are kind
of
important for later comparisons.
 Thanks again,
 Maria

 - Original Message -
 From: Bruce Fischl fis...@nmr.mgh.harvard.edu
 To: Maria Felber fel...@cbs.mpg.de
 Cc: freesurfer@nmr.mgh.harvard.edu
 Sent: Friday, September 9, 2011 2:13:05 PM
 Subject: Re: [Freesurfer] Talairach transformation

 Hi Maria

 as long as the tal xform is reasonable I wouldn't worry about it, unless
 for some reason you care a lot about the accuracy of the talairach
coords.

 cheers
 Bruce

 p.s. not sure why it would be smaller

 On Fri, 9 Sep 2011, Maria Felber wrote:

 Dear all,

 sorry, if that question came up before in the mailing list and I
simple have been unable to find the thread.

 Following the wiki 

[Freesurfer] Error with mri_glmfit-sim

2011-09-28 Thread Antonella Kis
Good morning Doug,

I tried running the -sim on my QDEC output (as you recommended me last days) 
but for some data the FDR gives me error (cannot calculate clusters statistics) 
so mri_glmfit-sim is not working either since the corrections by multiple 
comparisons is not working. What should I do in this case so I can get as 
output my cortical thickness values for the formed clusters at threshold 2, 
before multiple comparison?

Many thanks,
AK
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[Freesurfer] Folding Index and Gyrification index

2011-09-28 Thread Alan Francis
Hi Bruce, Nick  Doug:

How does Folding index differ from Gyrification index?

thanks,

Alan

BIDMC
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Re: [Freesurfer] fieldsign-sess: ERROR Surf/src mismatch

2011-09-28 Thread Douglas N Greve
Hi Michelle, this almost surely means that the surfaces are 
out-of-synch. You can try
recon-all -s subject -make all -dontrun
on one of your subjects.

If everything is in synch, then it should print
  make: Nothing to be done for `all'.

If not, it should print out the steps that it would have run (if not for 
the -dontrun option).

doug

Michelle Umali wrote:
 Hi Doug,
 I get the same MRISripZeros() and MRIScopyMRI Surf/src mismatch error
 when I use -sphere and not -occip in fieldsign-sess.

 What else should I try?

 Thank you.
 Michelle


 On Tue, Sep 27, 2011 at 8:51 PM, Douglas N Greve
 gr...@nmr.mgh.harvard.edu wrote:
   
 Is the occip patch out of synch with the subject? Does it run if you use
 -sphere instead of -occip?
 doug

 Michelle Umali wrote:
 
 Dear Freesurfers,
 This is related to my retinotopy analysis tksurfer-sess dimension
 mismatch error message.

 So another subject had these errors come up during fieldsign-sess
 selxavg3-sess -a rtopy.self.lh -s sjXX -force
 (which ran without error)

 then I ran fieldsign
 fieldsign-sess -a rtopy.self.lh -occip -s sjXX

 and got:
 ERROR: MRISripZeros(): dimension mismatch
 ERROR: MRIScopyMRI: Surf/Src dimension mismatch.
 ERROR: MRIScopyMRI: Surf/Src dimension mismatch.
 ERROR: MRIScopyMRI: Surf/Src dimension mismatch.
 ERROR: MRIScopyMRI: Surf/Src dimension mismatch.

 What may have caused this?

 Thanks.
 Michelle
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Re: [Freesurfer] aseg2feat for PPI seeds for FSL

2011-09-28 Thread Douglas N Greve


Michelle Umali wrote:
 Hi Freesurfers,
 I want to do a PPI in FSL FEAT using the V1 left and righ found
 generated in recon-all as seeds using:

 I know for each subject I have to get a timecourse for my seeds
 fslmeants -i filtered_func.nii.gz -o my_timecourse.txt -m V1_mask.nii.gz

 For each subject, I've run reg-feat2anat on my FEAT data from each of 4 runs.

 I have 2 questions:
 1) Does it matter which run's FEAT  I use for aseg2feat --feat featdir
 --aseg aparc+aseg to generate the binary masks for my seeds?
   
don't you need to run it on each feat to get a time course for each run?
 2) Does fslmeants need a special registered filtered_func.nii.gz from
 a cross-run GFEAT? If so, how do you specify it for this and then for
 actual PPI analysis in fsl?
   
Maybe I'm confused, but I thought you had to run it on the time course 
data (which is not in the GFEAT).
doug
 Thanks.
 Michelle
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gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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[Freesurfer] GM, WM and CSF segmentation for partial volume correction

2011-09-28 Thread _andreia_
Hello list,

Following this email that I found in the archives:


(...)
For the segmentation, FS still works voxelwise, but it's objective is  
to identify each structure as a whole, whereas SPM and FSL/FAST  
attempt to classify each voxel as being GM, WM or CSF. A short  
description of the method in FS is here:  
http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferAnalysisPipelineOverview#TheVolume-based.28Subcortical.29Stream
 You may want also to have a look at this paper:  
http://dx.doi.org/10.1016/S0896-6273(02)00569-X

Hope this helps!

All the best,

Anderson

I need to obtain the different % of tissue (GM, WM and CSF) inside one  
defined voxel. Does FS has a file that can be exported to Matlab to  
then get these values? Or only FSL/FAST and SPM have this type of info?

Thanks!
Andreia
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Re: [Freesurfer] correction

2011-09-28 Thread Douglas N Greve
Hi Viola,

there's some detailed info if you run
mri_glmfit-sim --help
mri_glmfit --help

mri_glmfit-sim runs mri_glmfit.

When you use mri_glmfit-sim with the --cache option, it uses simulations 
that are based on 10,000 iterations.

Here are some slides that give more detail
http://surfer.nmr.mgh.harvard.edu/pub/docs/freesurfer.groupanalysis.ppt

Here's the paper we reference
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/hayasaka.2003.ni.1014.clustersize.pdf

doug

Oertel, Viola wrote:
 Dear Freesurfers, 
 could you please give me detailed information about the Bonferroni or 
 clusterwise correction we can do in Freesurfer? How much iterations? Is that 
 cluster- oder voxelwise? Is there anywhere a detailed description about the 
 correction options?
 Best regards, 
 Viola
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Re: [Freesurfer] analysis.cfg not generated by mkanalysis-sess

2011-09-28 Thread Douglas N Greve
The 5.X version does not produce a cfg anymore, so everything is ok. You 
cannot use older versions of mkanalysis-sess with 5.X
doug

Po-Jang (Brown) Hsieh wrote:
 Dear all,

 I ran mkanalysis-sess (mkanalysis-sess -analysis junk -TR 2 -paradigm 
 para01.para -event-related -funcstem fmc -nconditions 3 -runlistfile 
 runlist_odd -fsd bold -fir 10 30 -native) but it did't not generate 
 analysis.cfg. The only file I can see after running this is 
 analysis.info http://analysis.info/.

 When I ran mkanalysis-sess.new, both analysis-info and analysis.cfg 
 are generated as fine. Could any one know how to solve this problem?

 ps. I'm running freesurfer5.1.0 on Mac OS X 10.6.8 (the 
 mkanalysis-sess.new is a copy from freesurfer4.5.0).

 Thanks!
 Brown
 

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Re: [Freesurfer] GM, WM and CSF segmentation for partial volume correction

2011-09-28 Thread Bruce Fischl
Hi Andreia

you could certainly change our segmentation labels to just these 3 classes 
easily enough in matlab. Then we have tools for computing partial volume 
fractions (I think mri_compute_volume_fractions)

cheers
Bruce


On Wed, 28 Sep 2011, _andre...@sapo.pt wrote:

 Hello list,

 Following this email that I found in the archives:


 (...)
 For the segmentation, FS still works voxelwise, but it's objective is
 to identify each structure as a whole, whereas SPM and FSL/FAST
 attempt to classify each voxel as being GM, WM or CSF. A short
 description of the method in FS is here:
 http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferAnalysisPipelineOverview#TheVolume-based.28Subcortical.29Stream
  You may want also to have a look at this paper:
 http://dx.doi.org/10.1016/S0896-6273(02)00569-X

 Hope this helps!

 All the best,

 Anderson

 I need to obtain the different % of tissue (GM, WM and CSF) inside one
 defined voxel. Does FS has a file that can be exported to Matlab to
 then get these values? Or only FSL/FAST and SPM have this type of info?

 Thanks!
 Andreia
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Re: [Freesurfer] analysis.cfg not generated by mkanalysis-sess

2011-09-28 Thread Po-Jang (Brown) Hsieh
Dear Doug,

Thanks very much! But without analysis.cfg, I cannot run selxave-sess... Am
I missing something here?

Brown

On Wed, Sep 28, 2011 at 11:36 PM, Douglas N Greve gr...@nmr.mgh.harvard.edu
 wrote:

 The 5.X version does not produce a cfg anymore, so everything is ok. You
 cannot use older versions of mkanalysis-sess with 5.X
 doug


 Po-Jang (Brown) Hsieh wrote:

 Dear all,

 I ran mkanalysis-sess (mkanalysis-sess -analysis junk -TR 2 -paradigm
 para01.para -event-related -funcstem fmc -nconditions 3 -runlistfile
 runlist_odd -fsd bold -fir 10 30 -native) but it did't not generate
 analysis.cfg. The only file I can see after running this is analysis.info
 http://analysis.info/.


 When I ran mkanalysis-sess.new, both analysis-info and analysis.cfg are
 generated as fine. Could any one know how to solve this problem?

 ps. I'm running freesurfer5.1.0 on Mac OS X 10.6.8 (the
 mkanalysis-sess.new is a copy from freesurfer4.5.0).

 Thanks!
 Brown
 --**--**
 

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 gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358 Fax: 617-726-7422

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Re: [Freesurfer] GM, WM and CSF segmentation for partial volume correction

2011-09-28 Thread Douglas N Greve
mri_compute_volume_fractions will compute the fractions for each of the tissue 
types, no need to alter the segmentations.
doug



Bruce Fischl wrote:
 Hi Andreia

 you could certainly change our segmentation labels to just these 3 classes 
 easily enough in matlab. Then we have tools for computing partial volume 
 fractions (I think mri_compute_volume_fractions)

 cheers
 Bruce


 On Wed, 28 Sep 2011, _andre...@sapo.pt wrote:

   
 Hello list,

 Following this email that I found in the archives:


 (...)
 For the segmentation, FS still works voxelwise, but it's objective is
 to identify each structure as a whole, whereas SPM and FSL/FAST
 attempt to classify each voxel as being GM, WM or CSF. A short
 description of the method in FS is here:
 http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferAnalysisPipelineOverview#TheVolume-based.28Subcortical.29Stream
  You may want also to have a look at this paper:
 http://dx.doi.org/10.1016/S0896-6273(02)00569-X

 Hope this helps!

 All the best,

 Anderson

 I need to obtain the different % of tissue (GM, WM and CSF) inside one
 defined voxel. Does FS has a file that can be exported to Matlab to
 then get these values? Or only FSL/FAST and SPM have this type of info?

 Thanks!
 Andreia
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gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

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Re: [Freesurfer] analysis.cfg not generated by mkanalysis-sess

2011-09-28 Thread Douglas N Greve
Hi Brown, you should not be mixing versions. There is no selxavg-sess in 
5.X. The new version is selxavg3-sess.
doug

Po-Jang (Brown) Hsieh wrote:
 Dear Doug,

 Thanks very much! But without analysis.cfg, I cannot run 
 selxave-sess... Am I missing something here?

 Brown

 On Wed, Sep 28, 2011 at 11:36 PM, Douglas N Greve 
 gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu wrote:

 The 5.X version does not produce a cfg anymore, so everything is
 ok. You cannot use older versions of mkanalysis-sess with 5.X
 doug


 Po-Jang (Brown) Hsieh wrote:

 Dear all,

 I ran mkanalysis-sess (mkanalysis-sess -analysis junk -TR 2
 -paradigm para01.para -event-related -funcstem fmc
 -nconditions 3 -runlistfile runlist_odd -fsd bold -fir 10 30
 -native) but it did't not generate analysis.cfg. The only file
 I can see after running this is analysis.info
 http://analysis.info http://analysis.info/.


 When I ran mkanalysis-sess.new, both analysis-info and
 analysis.cfg are generated as fine. Could any one know how to
 solve this problem?

 ps. I'm running freesurfer5.1.0 on Mac OS X 10.6.8 (the
 mkanalysis-sess.new is a copy from freesurfer4.5.0).

 Thanks!
 Brown
 
 

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 Phone Number: 617-724-2358 Fax: 617-726-7422

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 --
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 https://sites.google.com/site/brainconsciousnesslab/


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Re: [Freesurfer] Folding Index and Gyrification index

2011-09-28 Thread Nick Schmansky
have a look at this page:

https://surfer.nmr.mgh.harvard.edu/fswiki/LGI

folding index is typically a single number summarizing the amount of
folding overall on a surface.  freesurfer puts these measures in
subjid/stats/?h.curv.stats.

gyrification index is a new method created by maria schaer to create a
surface-based measure of folding (points across a surface describing the
local folding measures).

n.


On Wed, 2011-09-28 at 11:05 -0400, Alan Francis wrote:
 Hi Bruce, Nick  Doug:
 
 How does Folding index differ from Gyrification index? 
 
 thanks,
 
 Alan
 
 BIDMC
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Re: [Freesurfer] strange freeview issue

2011-09-28 Thread Satrajit Ghosh
thanks nick.

tried with 5.1.0 same issue. here is the output from glxgears.

$ glxgears
Error: couldn't get an RGB, Double-buffered visual

i am beginning to suspect it as a driver issue.

cheers,

satra


On Wed, Sep 28, 2011 at 11:17 AM, Nick Schmansky
ni...@nmr.mgh.harvard.eduwrote:

 i'm able to replicate what you see on my mac (leopard, w/ XQuartz)
 connecting via ssh -Y to a linux machine and running fs v5.0.0.
 however, freeview works in this setup using fs 5.1.0.  the change
 between version is that freeview now uses Qt (instead of Wx).  can you
 switch to v5.1.0?  or copy the freeview from 5.1.0 to your 5.0.0
 installation?  you would need to copy:

 freesurfer/lib/qt
 freesurfer/bin/freeview
 freesurfer/bin/freeview.bin
 freesurver/bin/qt_setup.csh

 n.



 On Tue, 2011-09-27 at 20:40 -0400, Satrajit Ghosh wrote:
  hi,
 
 
  we are seeing a strange freeview issue at mit and just wanted to check
  if anybody else has seen this. we are running natty narwhal (ubuntu
  11.04).
 
 
  details here:
 
 
  https://github.com/gablab/mindhive/issues/1
 
 
  cheers,
 
  satra
 
 
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 e-mail
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Re: [Freesurfer] strange freeview issue

2011-09-28 Thread Nick Schmansky
its a shot in the dark, but you could try updating the mac with XQuartz,
which seems to be much better for X stuff than the default X
installation.  doing so is a necessity for running freesurfer locally on
the mac:

https://surfer.nmr.mgh.harvard.edu/fswiki/MacTksurfer

that page fixes a different issue, but its X related.

also, on the linux machine, make sure the /etc/X11/xorg.conf file has

Load   glx

in the Section Module

n.


On Wed, 2011-09-28 at 11:52 -0400, Satrajit Ghosh wrote:
 thanks nick.
 
 
 tried with 5.1.0 same issue. here is the output from glxgears.
 
 
 $ glxgears 
 Error: couldn't get an RGB, Double-buffered visual
 
 
 i am beginning to suspect it as a driver issue.
 
 
 cheers,
 
 satra
 
 
 On Wed, Sep 28, 2011 at 11:17 AM, Nick Schmansky
 ni...@nmr.mgh.harvard.edu wrote:
 i'm able to replicate what you see on my mac (leopard, w/
 XQuartz)
 connecting via ssh -Y to a linux machine and running fs
 v5.0.0.
 however, freeview works in this setup using fs 5.1.0.  the
 change
 between version is that freeview now uses Qt (instead of Wx).
  can you
 switch to v5.1.0?  or copy the freeview from 5.1.0 to your
 5.0.0
 installation?  you would need to copy:
 
 freesurfer/lib/qt
 freesurfer/bin/freeview
 freesurfer/bin/freeview.bin
 freesurver/bin/qt_setup.csh
 
 n.
 
 
 
 
 On Tue, 2011-09-27 at 20:40 -0400, Satrajit Ghosh wrote:
  hi,
 
 
  we are seeing a strange freeview issue at mit and just
 wanted to check
  if anybody else has seen this. we are running natty narwhal
 (ubuntu
  11.04).
 
 
  details here:
 
 
  https://github.com/gablab/mindhive/issues/1
 
 
  cheers,
 
  satra
 
 
 
 
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  Freesurfer mailing list
  Freesurfer@nmr.mgh.harvard.edu
  https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
 
 
 
 The information in this e-mail is intended only for the person
 to whom it is
 addressed. If you believe this e-mail was sent to you in error
 and the e-mail
 contains patient information, please contact the Partners
 Compliance HelpLine at
 http://www.partners.org/complianceline . If the e-mail was
 sent to you in error
 but does not contain patient information, please contact the
 sender and properly
 dispose of the e-mail.
 
 
 
 

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Re: [Freesurfer] Error with mri_glmfit-sim

2011-09-28 Thread Douglas N Greve
What does FDR have to do with it? FDR should not come into play in this.
doug

Antonella Kis wrote:
 Good morning Doug,

 I tried running the -sim on my QDEC output (as you recommended me last 
 days) but for some data the FDR gives me error (cannot calculate 
 clusters statistics) so mri_glmfit-sim is not working either since the 
 corrections by multiple comparisons is not working. What should I do 
 in this case so I can get as output my cortical thickness values for 
 the formed clusters at threshold 2, before multiple comparison?

 Many thanks,
 AK

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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[Freesurfer] Error with mri_glmfit-sim

2011-09-28 Thread Antonella Kis





Good afternoon,

I tried running the -sim on my QDEC output (as  recommended last days) but for 
some data the FDR gives me error (cannot calculate clusters statistics) so 
mri_glmfit-sim is not working either since the corrections by multiple 
comparisons is not working. What should I do in this case so I can get as 
output my cortical thickness values for the formed clusters at threshold 2, 
before multiple comparison?

Many thanks,
AK___
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Re: [Freesurfer] GM, WM and CSF segmentation for partial volume correction

2011-09-28 Thread _andreia_
Thanks Bruce and Douglas!

Andreia



Citando Douglas N Greve gr...@nmr.mgh.harvard.edu:

 mri_compute_volume_fractions will compute the fractions for each of  
 the tissue types, no need to alter the segmentations.
 doug



 Bruce Fischl wrote:
 Hi Andreia

 you could certainly change our segmentation labels to just these 3  
 classes easily enough in matlab. Then we have tools for computing  
 partial volume fractions (I think mri_compute_volume_fractions)

 cheers
 Bruce


 On Wed, 28 Sep 2011, _andre...@sapo.pt wrote:


 Hello list,

 Following this email that I found in the archives:


 (...)
 For the segmentation, FS still works voxelwise, but it's objective is
 to identify each structure as a whole, whereas SPM and FSL/FAST
 attempt to classify each voxel as being GM, WM or CSF. A short
 description of the method in FS is here:
 http://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferAnalysisPipelineOverview#TheVolume-based.28Subcortical.29Stream
  You may want also to have a look at this  
 paper:
 http://dx.doi.org/10.1016/S0896-6273(02)00569-X

 Hope this helps!

 All the best,

 Anderson

 I need to obtain the different % of tissue (GM, WM and CSF) inside one
 defined voxel. Does FS has a file that can be exported to Matlab to
 then get these values? Or only FSL/FAST and SPM have this type of info?

 Thanks!
 Andreia
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 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer




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 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358 Fax: 617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html



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Re: [Freesurfer] Error with mri_glmfit-sim

2011-09-28 Thread Douglas N Greve
again, FDR should have nothing to do with it. If you want a voxel-wise 
threshold at 2, just set that threshold when you run mri_glmfit-sim with 
--cache 2 sign where sign is pos, neg, or abs
doug

Antonella Kis wrote:
 Hi Doug,

 Thanks again for helping. I am trying to use QDEC but there are no 
 clusters surviving after FDR (it says statics cannot be done so gives 
 me error by running FDR). So I am trying  to get the thickness values 
 only for the clusters that are formed in QDEC after setting up a 
 threshold = 2 (before running FDR). In order to do this you suggested 
 me to run mri_glmfit-sim on the QDEC results. The only problem is that 
 I cannot run the -sim if there is no FDR data (stats) so I cannot 
 cache the clusters formed only by thresh 2 in QDEC. Is theer a way to 
 do it?

 Many thanks,
 AK

 
 *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com
 *Cc:* freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edu
 *Sent:* Wednesday, September 28, 2011 12:06 PM
 *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim

 What does FDR have to do with it? FDR should not come into play in this.
 doug

 Antonella Kis wrote:
  Good morning Doug,
 
  I tried running the -sim on my QDEC output (as you recommended me last
  days) but for some data the FDR gives me error (cannot calculate
  clusters statistics) so mri_glmfit-sim is not working either since the
  corrections by multiple comparisons is not working. What should I do
  in this case so I can get as output my cortical thickness values for
  the formed clusters at threshold 2, before multiple comparison?
 
  Many thanks,
  AK

 -- 
 Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358
 Fax: 617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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 e-mail
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Fax: 617-726-7422

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Re: [Freesurfer] Folding Index and Gyrification index

2011-09-28 Thread Donna Dierker
My understanding is that GI is also a global summary stat across the whole hem, 
while lGI is *local* GI (vertex-wise).  It measures how folded the cortex is at 
that vertex.  GI and lGI are based on area, while the folding index is based on 
curvature.  Truly different measures.

Gyrification Index (GI) = Pial surface area / Convex hull surface area
(Zilles et al., 1988)

Folding Index (FI) = |kmax|(|kmax|-|kmin|)
Van Essen and Drury 1997

On Sep 28, 2011, at 10:48 AM, Nick Schmansky wrote:

 have a look at this page:
 
 https://surfer.nmr.mgh.harvard.edu/fswiki/LGI
 
 folding index is typically a single number summarizing the amount of
 folding overall on a surface.  freesurfer puts these measures in
 subjid/stats/?h.curv.stats.
 
 gyrification index is a new method created by maria schaer to create a
 surface-based measure of folding (points across a surface describing the
 local folding measures).
 
 n.
 
 
 On Wed, 2011-09-28 at 11:05 -0400, Alan Francis wrote:
 Hi Bruce, Nick  Doug:
 
 How does Folding index differ from Gyrification index? 
 
 thanks,
 
 Alan
 
 BIDMC
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Re: [Freesurfer] Folding Index and Gyrification index

2011-09-28 Thread Donna Dierker
Correction:  FI = Sum-over-vertices[ |kmax|(|kmax|-|kmin|)]/SurfaceArea

On Sep 28, 2011, at 1:38 PM, Donna Dierker wrote:

 My understanding is that GI is also a global summary stat across the whole 
 hem, while lGI is *local* GI (vertex-wise).  It measures how folded the 
 cortex is at that vertex.  GI and lGI are based on area, while the folding 
 index is based on curvature.  Truly different measures.
 
 Gyrification Index (GI) = Pial surface area / Convex hull surface area
   (Zilles et al., 1988)
 
 Folding Index (FI) = |kmax|(|kmax|-|kmin|)
   Van Essen and Drury 1997
 
 On Sep 28, 2011, at 10:48 AM, Nick Schmansky wrote:
 
 have a look at this page:
 
 https://surfer.nmr.mgh.harvard.edu/fswiki/LGI
 
 folding index is typically a single number summarizing the amount of
 folding overall on a surface.  freesurfer puts these measures in
 subjid/stats/?h.curv.stats.
 
 gyrification index is a new method created by maria schaer to create a
 surface-based measure of folding (points across a surface describing the
 local folding measures).
 
 n.
 
 
 On Wed, 2011-09-28 at 11:05 -0400, Alan Francis wrote:
 Hi Bruce, Nick  Doug:
 
 How does Folding index differ from Gyrification index? 
 
 thanks,
 
 Alan
 
 BIDMC
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 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
 
 
 The information in this e-mail is intended only for the person to whom it is
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 contains patient information, please contact the Partners Compliance 
 HelpLine at
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Re: [Freesurfer] THANKS

2011-09-28 Thread Douglas N Greve
*By default, FreeSurfer compputes and uses a two-tailed p-value. When 
you specify a sign, it lowers the threshold that you give it to reflect 
a one-tailed test. Probably what happened was that you had two clusters 
close to each other that merged together with the lower threshold.
doug
*
Antonella Kis wrote:
 Dear Doug,

 Finally I've got it. But there is one more problem: when I run the 
 QDEC with Min threshold 2 neg, I am getting 2  clusters, while when I 
 am running the results from QDEC(under Untitled.glmdir) with the -sim:

 mri_glmfit-sim \
 --glmdir Untitled.glmdir \
 --cache 2 pos \
 --overwrite

 I am getting only one of the clusters. Can you please advise me what 
 is going on or what should I correct?

 Many thanks,
 AK
 
 *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com; freesurfer 
 freesurfer@nmr.mgh.harvard.edu
 *Sent:* Wednesday, September 28, 2011 1:33 PM
 *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim

 again, FDR should have nothing to do with it. If you want a voxel-wise 
 threshold at 2, just set that threshold when you run mri_glmfit-sim 
 with --cache 2 sign where sign is pos, neg, or abs
 doug

 Antonella Kis wrote:
  Hi Doug,
 
  Thanks again for helping. I am trying to use QDEC but there are no 
 clusters surviving after FDR (it says statics cannot be done so gives 
 me error by running FDR). So I am trying  to get the thickness values 
 only for the clusters that are formed in QDEC after setting up a 
 threshold = 2 (before running FDR). In order to do this you suggested 
 me to run mri_glmfit-sim on the QDEC results. The only problem is that 
 I cannot run the -sim if there is no FDR data (stats) so I cannot 
 cache the clusters formed only by thresh 2 in QDEC. Is theer a way to 
 do it?
 
  Many thanks,
  AK
 
  
  *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
  *To:* Antonella Kis ator...@yahoo.com mailto:ator...@yahoo.com
  *Cc:* freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 freesurfer@nmr.mgh.harvard.edu mailto:freesurfer@nmr.mgh.harvard.edu
  *Sent:* Wednesday, September 28, 2011 12:06 PM
  *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim
 
  What does FDR have to do with it? FDR should not come into play in this.
  doug
 
  Antonella Kis wrote:
   Good morning Doug,
  
   I tried running the -sim on my QDEC output (as you recommended me last
   days) but for some data the FDR gives me error (cannot calculate
   clusters statistics) so mri_glmfit-sim is not working either since the
   corrections by multiple comparisons is not working. What should I do
   in this case so I can get as output my cortical thickness values for
   the formed clusters at threshold 2, before multiple comparison?
  
   Many thanks,
   AK
 
  -- Douglas N. Greve, Ph.D.
  MGH-NMR Center
  gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
  Phone Number: 617-724-2358
  Fax: 617-726-7422
 
  Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
  FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
 
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 mailto:Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu
  https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
 
 
  The information in this e-mail is intended only for the person to 
 whom it is
  addressed. If you believe this e-mail was sent to you in error and 
 the e-mail
  contains patient information, please contact the Partners Compliance 
 HelpLine at
  http://www.partners.org/complianceline . If the e-mail was sent to 
 you in error
  but does not contain patient information, please contact the sender 
 and properly
  dispose of the e-mail.
 
 
 

 -- Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358 Fax: 617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html




-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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Re: [Freesurfer] Error with mri_glmfit-sim

2011-09-28 Thread Douglas N Greve
No, unfortunately not.
doug

jm wrote:
 Doug:

 I have processed 20 subjects. By mistake, five of them with LAS
 orientation and 15 RAS orientation.RAS that's right in my case. 
 I could change name of files in '/surf' folder from left to right in the
 first ones? or I need do it over? for instance: I could change name of
 file rh.thickness.fwhm25.fsaverage to lh.thickness.fwhm25.fsaverage? or
 that have others implications to statistical analysis outcomes

 thanks

  

 On Wed, 2011-09-28 at 13:33 -0400, Douglas N Greve wrote:
   
 again, FDR should have nothing to do with it. If you want a voxel-wise 
 threshold at 2, just set that threshold when you run mri_glmfit-sim with 
 --cache 2 sign where sign is pos, neg, or abs
 doug

 Antonella Kis wrote:
 
 Hi Doug,

 Thanks again for helping. I am trying to use QDEC but there are no 
 clusters surviving after FDR (it says statics cannot be done so gives 
 me error by running FDR). So I am trying  to get the thickness values 
 only for the clusters that are formed in QDEC after setting up a 
 threshold = 2 (before running FDR). In order to do this you suggested 
 me to run mri_glmfit-sim on the QDEC results. The only problem is that 
 I cannot run the -sim if there is no FDR data (stats) so I cannot 
 cache the clusters formed only by thresh 2 in QDEC. Is theer a way to 
 do it?

 Many thanks,
 AK

 
 *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com
 *Cc:* freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edu
 *Sent:* Wednesday, September 28, 2011 12:06 PM
 *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim

 What does FDR have to do with it? FDR should not come into play in this.
 doug

 Antonella Kis wrote:
   
 Good morning Doug,

 I tried running the -sim on my QDEC output (as you recommended me last
 days) but for some data the FDR gives me error (cannot calculate
 clusters statistics) so mri_glmfit-sim is not working either since the
 corrections by multiple comparisons is not working. What should I do
 in this case so I can get as output my cortical thickness values for
 the formed clusters at threshold 2, before multiple comparison?

 Many thanks,
 AK
 
 -- 
 Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358
 Fax: 617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

 ___
 Freesurfer mailing list
 Freesurfer@nmr.mgh.harvard.edu mailto:Freesurfer@nmr.mgh.harvard.edu
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


 The information in this e-mail is intended only for the person to whom 
 it is
 addressed. If you believe this e-mail was sent to you in error and the 
 e-mail
 contains patient information, please contact the Partners Compliance 
 HelpLine at
 http://www.partners.org/complianceline . If the e-mail was sent to you 
 in error
 but does not contain patient information, please contact the sender 
 and properly
 dispose of the e-mail.



   



   

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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Re: [Freesurfer] aseg2feat for PPI seeds for FSL

2011-09-28 Thread Michelle Umali
Dear Doug and the Freesurfers,
Ok, so is there a special filtered_func.nii generated from reg-feat2anat for
each run or can I just use the feat?

When one does a cross-subject PPI in FSL and enter each run from each
person, isn't everyone in a different space?  How do you account for this
when doing setting up the PPI feat?

Thanks.
Michelle




 Michelle Umali wrote:

 Hi Freesurfers,
 I want to do a PPI in FSL FEAT using the V1 left and righ found
 generated in recon-all as seeds using:

 I know for each subject I have to get a timecourse for my seeds
 fslmeants -i filtered_func.nii.gz -o my_timecourse.txt -m V1_mask.nii.gz

 For each subject, I've run reg-feat2anat on my FEAT data from each of 4
runs.

 I have 2 questions:
 1) Does it matter which run's FEAT  I use for aseg2feat --feat featdir
 --aseg aparc+aseg to generate the binary masks for my seeds?


 don't you need to run it on each feat to get a time course for each run?

 2) Does fslmeants need a special registered filtered_func.nii.gz from
 a cross-run GFEAT? If so, how do you specify it for this and then for
 actual PPI analysis in fsl?


 Maybe I'm confused, but I thought you had to run it on the time course
data (which is not in the GFEAT).
 doug

 Thanks.
 Michelle
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 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer 
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 --
 Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358 tel:617-724-2358 Fax:
617-726-7422 tel:617-726-7422

 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html



 The information in this e-mail is intended only for the person to whom it
is
 addressed. If you believe this e-mail was sent to you in error and the
e-mail
 contains patient information, please contact the Partners Compliance
HelpLine at
 http://www.partners.org/complianceline . If the e-mail was sent to you in
error
 but does not contain patient information, please contact the sender and
properly
 dispose of the e-mail.


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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] aseg2feat for PPI seeds for FSL

2011-09-28 Thread Douglas N Greve


Michelle Umali wrote:
 Dear Doug and the Freesurfers,
 Ok, so is there a special filtered_func.nii generated from 
 reg-feat2anat for each run or can I just use the feat?
No, just use the FEAT one.

 When one does a cross-subject PPI in FSL and enter each run from each 
 person, isn't everyone in a different space?  How do you account for 
 this when doing setting up the PPI feat?
Aren't you just getting a single time course? I have not done PPI 
analysis before, so I might not know what is required.
doug

 Thanks.
 Michelle


 
 
  Michelle Umali wrote:
 
  Hi Freesurfers,
  I want to do a PPI in FSL FEAT using the V1 left and righ found
  generated in recon-all as seeds using:
 
  I know for each subject I have to get a timecourse for my seeds
  fslmeants -i filtered_func.nii.gz -o my_timecourse.txt -m 
 V1_mask.nii.gz
 
  For each subject, I've run reg-feat2anat on my FEAT data from each 
 of 4 runs.
 
  I have 2 questions:
  1) Does it matter which run's FEAT  I use for aseg2feat --feat featdir
  --aseg aparc+aseg to generate the binary masks for my seeds?
   
 
  don't you need to run it on each feat to get a time course for each run?
 
  2) Does fslmeants need a special registered filtered_func.nii.gz from
  a cross-run GFEAT? If so, how do you specify it for this and then for
  actual PPI analysis in fsl?
   
 
  Maybe I'm confused, but I thought you had to run it on the time 
 course data (which is not in the GFEAT).
  doug
 
  Thanks.
  Michelle
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 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer 
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
 
 
   
 
  --
  Douglas N. Greve, Ph.D.
  MGH-NMR Center
  gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
  Phone Number: 617-724-2358 tel:617-724-2358 Fax: 
 617-726-7422 tel:617-726-7422
 
  Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting 
 http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
  FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html 
 http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html
 
 
 
  The information in this e-mail is intended only for the person to 
 whom it is
  addressed. If you believe this e-mail was sent to you in error and 
 the e-mail
  contains patient information, please contact the Partners Compliance 
 HelpLine at
  http://www.partners.org/complianceline . If the e-mail was sent to 
 you in error
  but does not contain patient information, please contact the sender 
 and properly
  dispose of the e-mail.
 
 
 

 ___
 Freesurfer mailing list
 Freesurfer@nmr.mgh.harvard.edu
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358 
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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[Freesurfer] Mcsrch error during recon-all

2011-09-28 Thread Warren Winter
Hi,

Each time I have run recon-all on our subjects, I end up with the same slew of 
error messages underneath Computing MAP estimate using [x number of] samples 
and underneath EM alignment process:

IFLAG= -1  LINE SEARCH FAILED. SEE DOCUMENTATION OF ROUTINE MCSRCH ERROR 
RETURN OF LINE SEARCH: INFO= 3 POSSIBLE CAUSES: FUNCTION OR GRADIENT ARE 
INCORRECT OR INCORRECT TOLERANCES

At the very end of the log file I see:

Loading source label.
Abort
Linux rc-twice 2.6.39.2-mosix #1 SMP Wed Jun 29 11:53:08 EDT 2011 x86_64 x86_64 
x86_64 GNU/Linux

recon-all -s 5 exited with ERRORS at Tue Sep 27 03:23:46 EDT 2011

Any help on this would be greatly appreciated.

Best,

Warren

--
Warren Winter
Lab Coordinator
Children's Hospital Boston
Division of Developmental Medicine
1 Autumn Street, AU 650
Boston, MA 02215
857-218-5224

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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
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but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] THANKS

2011-09-28 Thread Douglas N Greve
The change in threshold is always 0.3. Eg, to go from a two-tailed 
threshold of 2.0 to a one-tailed threshold, you would subtract .3 from 
2.0 (and so 1.7). Is this what you mean?

Antonella Kis wrote:
 I see. Is there a way that I can get/read both clusters sin other 
 words can I eliminate this inconvenient of two-tailed p-value?

 Thanks,
 AK

 
 *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com; freesurfer 
 freesurfer@nmr.mgh.harvard.edu
 *Sent:* Wednesday, September 28, 2011 2:59 PM
 *Subject:* Re: [Freesurfer] THANKS

 *By default, FreeSurfer compputes and uses a two-tailed p-value. When
 you specify a sign, it lowers the threshold that you give it to reflect
 a one-tailed test. Probably what happened was that you had two clusters
 close to each other that merged together with the lower threshold.
 doug
 *
 Antonella Kis wrote:
  Dear Doug,
 
  Finally I've got it. But there is one more problem: when I run the
  QDEC with Min threshold 2 neg, I am getting 2  clusters, while when I
  am running the results from QDEC(under Untitled.glmdir) with the -sim:
 
  mri_glmfit-sim \
  --glmdir Untitled.glmdir \
  --cache 2 pos \
  --overwrite
 
  I am getting only one of the clusters. Can you please advise me what
  is going on or what should I correct?
 
  Many thanks,
  AK
  
  *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
  *To:* Antonella Kis ator...@yahoo.com mailto:ator...@yahoo.com; 
 freesurfer
  freesurfer@nmr.mgh.harvard.edu mailto:freesurfer@nmr.mgh.harvard.edu
  *Sent:* Wednesday, September 28, 2011 1:33 PM
  *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim
 
  again, FDR should have nothing to do with it. If you want a voxel-wise
  threshold at 2, just set that threshold when you run mri_glmfit-sim
  with --cache 2 sign where sign is pos, neg, or abs
  doug
 
  Antonella Kis wrote:
   Hi Doug,
  
   Thanks again for helping. I am trying to use QDEC but there are no
  clusters surviving after FDR (it says statics cannot be done so gives
  me error by running FDR). So I am trying  to get the thickness values
  only for the clusters that are formed in QDEC after setting up a
  threshold = 2 (before running FDR). In order to do this you suggested
  me to run mri_glmfit-sim on the QDEC results. The only problem is that
  I cannot run the -sim if there is no FDR data (stats) so I cannot
  cache the clusters formed only by thresh 2 in QDEC. Is theer a way to
  do it?
  
   Many thanks,
   AK
  
   
 
   *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
  mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
   *To:* Antonella Kis ator...@yahoo.com mailto:ator...@yahoo.com 
 mailto:ator...@yahoo.com mailto:ator...@yahoo.com
   *Cc:* freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
  mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
  freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
   *Sent:* Wednesday, September 28, 2011 12:06 PM
   *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim
  
   What does FDR have to do with it? FDR should not come into play in 
 this.
   doug
  
   Antonella Kis wrote:
Good morning Doug,
   
I tried running the -sim on my QDEC output (as you recommended 
 me last
days) but for some data the FDR gives me error (cannot calculate
clusters statistics) so mri_glmfit-sim is not working either 
 since the
corrections by multiple comparisons is not working. What should I do
in this case so I can get as output my cortical thickness values for
the formed clusters at threshold 2, before multiple comparison?
   
Many thanks,
AK
  
   -- Douglas N. Greve, Ph.D.
   MGH-NMR Center
   gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
  mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu
   Phone Number: 617-724-2358
   Fax: 617-726-7422
  
   Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
   FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
  
   ___
   Freesurfer mailing list
   Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu
  mailto:Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu
  mailto:Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu
  mailto:Freesurfer@nmr.mgh.harvard.edu 
 mailto:Freesurfer@nmr.mgh.harvard.edu
   

Re: [Freesurfer] THANKS

2011-09-28 Thread Douglas N Greve
Oh, sorry, I precompute the tables with certain fixed voxel-wise 
thresholds. But it seems like you may want to use 2.3. Why 1.7? If you 
want it to match what you see in QDEC at a threshold of 2.0, then you 
should spec 2.3.

Antonella Kis wrote:
 I am not sure but I tried that and it gives me error:


 ? --glmdir Untitled.glmdir \
 ? --cache 1.7 neg\
 ? --overwrite
 ERROR: thresh = 1.7, must be 1.3, 2.0, 2.3, 3.0, 3.3, 4.0
 So how should I fix that?

 Many thanks!
 AK
 
 *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu
 *To:* Antonella Kis ator...@yahoo.com; freesurfer 
 freesurfer@nmr.mgh.harvard.edu
 *Sent:* Wednesday, September 28, 2011 4:07 PM
 *Subject:* Re: [Freesurfer] THANKS

 The change in threshold is always 0.3. Eg, to go from a two-tailed 
 threshold of 2.0 to a one-tailed threshold, you would subtract .3 from 
 2.0 (and so 1.7). Is this what you mean?

 Antonella Kis wrote:
  I see. Is there a way that I can get/read both clusters sin other 
 words can I eliminate this inconvenient of two-tailed p-value?
 
  Thanks,
  AK
 
  
  *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
  *To:* Antonella Kis ator...@yahoo.com mailto:ator...@yahoo.com; 
 freesurfer freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
  *Sent:* Wednesday, September 28, 2011 2:59 PM
  *Subject:* Re: [Freesurfer] THANKS
 
  *By default, FreeSurfer compputes and uses a two-tailed p-value. When
  you specify a sign, it lowers the threshold that you give it to reflect
  a one-tailed test. Probably what happened was that you had two clusters
  close to each other that merged together with the lower threshold.
  doug
  *
  Antonella Kis wrote:
   Dear Doug,
  
   Finally I've got it. But there is one more problem: when I run the
   QDEC with Min threshold 2 neg, I am getting 2  clusters, while when I
   am running the results from QDEC(under Untitled.glmdir) with the -sim:
  
   mri_glmfit-sim \
   --glmdir Untitled.glmdir \
   --cache 2 pos \
   --overwrite
  
   I am getting only one of the clusters. Can you please advise me what
   is going on or what should I correct?
  
   Many thanks,
   AK
   
 
   *From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
   *To:* Antonella Kis ator...@yahoo.com mailto:ator...@yahoo.com 
 mailto:ator...@yahoo.com mailto:ator...@yahoo.com; freesurfer
   freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
   *Sent:* Wednesday, September 28, 2011 1:33 PM
   *Subject:* Re: [Freesurfer] Error with mri_glmfit-sim
  
   again, FDR should have nothing to do with it. If you want a voxel-wise
   threshold at 2, just set that threshold when you run mri_glmfit-sim
   with --cache 2 sign where sign is pos, neg, or abs
   doug
  
   Antonella Kis wrote:
Hi Doug,
   
Thanks again for helping. I am trying to use QDEC but there are no
   clusters surviving after FDR (it says statics cannot be done so gives
   me error by running FDR). So I am trying  to get the thickness values
   only for the clusters that are formed in QDEC after setting up a
   threshold = 2 (before running FDR). In order to do this you suggested
   me to run mri_glmfit-sim on the QDEC results. The only problem is that
   I cannot run the -sim if there is no FDR data (stats) so I cannot
   cache the clusters formed only by thresh 2 in QDEC. Is theer a way to
   do it?
   
Many thanks,
AK
   

 
*From:* Douglas N Greve gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
   mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu mailto:gr...@nmr.mgh.harvard.edu 
 mailto:gr...@nmr.mgh.harvard.edu
*To:* Antonella Kis ator...@yahoo.com 
 mailto:ator...@yahoo.com mailto:ator...@yahoo.com 
 mailto:ator...@yahoo.com mailto:ator...@yahoo.com 
 mailto:ator...@yahoo.com mailto:ator...@yahoo.com 
 mailto:ator...@yahoo.com
*Cc:* freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
   mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu
   freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 mailto:freesurfer@nmr.mgh.harvard.edu 
 

Re: [Freesurfer] Mcsrch error during recon-all

2011-09-28 Thread Nick Schmansky
the IFLAG messages can be ignored if mri_em_register is not exiting with
error.  which command is running that is exiting with error?  can you
send that command line from the recon-all.log file?

n.

On Wed, 2011-09-28 at 16:02 -0400, Warren Winter wrote:
 Hi,
 
 
 Each time I have run recon-all on our subjects, I end up with the same
 slew of error messages underneath Computing MAP estimate using [x
 number of] samples and underneath EM alignment process:
 
 
 IFLAG= -1  LINE SEARCH FAILED. SEE DOCUMENTATION OF ROUTINE MCSRCH
 ERROR RETURN OF LINE SEARCH: INFO= 3 POSSIBLE CAUSES: FUNCTION OR
 GRADIENT ARE INCORRECT OR INCORRECT TOLERANCES
 
 
 At the very end of the log file I see:
 
 
 Loading source label.
 Abort
 Linux rc-twice 2.6.39.2-mosix #1 SMP Wed Jun 29 11:53:08 EDT 2011
 x86_64 x86_64 x86_64 GNU/Linux
 
 
 recon-all -s 5 exited with ERRORS at Tue Sep 27 03:23:46 EDT 2011
 
 
 Any help on this would be greatly appreciated.
 
 
 Best,
 
 
 Warren
 
 --
 Warren Winter
 Lab Coordinator
 Children's Hospital Boston
 Division of Developmental Medicine
 1 Autumn Street, AU 650
 Boston, MA 02215
 857-218-5224
 
 
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Re: [Freesurfer] Fwd: Talairach transformation

2011-09-28 Thread Bruce Fischl

Hi Maria

have you tried running without the talairach stuff? Try -notalairach and 
see if it works for you


cheers
Bruce
On Wed, 28 Sep 2011, Maria Felber wrote:


Dear Ms. Kakunoori,

sorry to bother you again, but as I did not get a reply to my last message to 
everyone so far troubled with my question, I am trying here for a second time.
It is indeed the case, that all my data were scanned with a 3T. And if that is 
indeed the problem Dr. Snyder figured out, then what can I do about it? Or is 
anyone already working on this problem? I can hardly imagine I am the only one 
recording with a 3T instead of a 1.5T.
Yours sincerely,
Maria Felber

- Forwarded Message -
From: Maria Felber fel...@cbs.mpg.de
To: Avi Snyder a...@npg.wustl.edu
Cc: Sita Kakunoori\, fel...@cbs.mpg.de, \Avi Snyder\ a...@npg.wustl.edu, Bruce 
Fischl s...@nmr.mgh.harvard.edu, freesurfer@nmr.mgh.harvard.edu
Sent: Thursday, September 15, 2011 10:46:55 AM
Subject: Re: [Freesurfer]  Talairach transformation

Dear all,

indeed all my T1-scans were recorded with a 3T scanner. So what can I do about 
it or do you have something in progress which would fix this problem anytime 
soon?
Thanks,
Maria

- Original Message -
From: Avi Snyder a...@npg.wustl.edu
To: Sita Kakunoori s...@nmr.mgh.harvard.edu, fel...@cbs.mpg.de, Avi Snyder 
a...@npg.wustl.edu
Cc: Bruce Fischl fis...@nmr.mgh.harvard.edu
Sent: Tuesday, September 13, 2011 11:03:28 PM
Subject: Re: [Freesurfer]  Talairach transformation

Hi Sita,

Wrong-stretch (e.g., too fat or too thin) MP-RAGE atlas transforms are
expected if the contrast properties of the sample image are far from those
of the target. This condition can easily occur if the target is based on
1.5T data and the sample is acquired at 3T. (3T but not 1.5T T1W images
tend to be relatively bright in the center of the head.) Gd++ contrasted
MP-RAGE scans routinely do not produce decent atlas transforms unless
special measures are taken. A FreeSurfer fix for this problem is
theoretically feasible.

Avi
---
On 9/13/11 2:26 PM, Sita Kakunoori s...@nmr.mgh.harvard.edu wrote:


I might have seen this in a dataset. I am cc'ing Dr.Avi Anyder on this
e-mail.
Hi Dr.Snyder, Not sure if you remember but we saw something similar in a
dataset here at the center where the talairach was much smaller than the
orig.mgz volume and you created a new talairach template to be used with
that dataset. I just wondered if this issue is similar to that.

Thanks much,
Sita.
-- Forwarded message --
Date: Tue, 13 Sep 2011 16:27:17 +0200 (CEST)
From: Maria Felber fel...@cbs.mpg.de
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer]  Talairach transformation

Hi Bruce,

so we are back at the beginning. After I ran recon-all -all, I did
exactly that and checked the xform using tkregister2. And here I always
see that my talairach volume (the transform) is always smaller, which can
be very well seen as the orig surfaces of the subjects are always a
little outside the brain and reach well into the skull areas. Of course I
can make the adjustments as descriped in the short instructions. But this
also means I ran the recon-all precess anew for another 30 h per subject.
And that is the reason, why I asked if this is normal that the tailarach
transform is a) always smaller than the original brain, and b) if I can
make any adjustments to prevent that from happening and thus saving
another 30h per subject.
In short: How acurate hat the talairach.xfm has to be and is it possible
to change some parameters to make this transformation a little more
accurate while running the recon-all process only once?
Best,
Maria


- Original Message -
From: Bruce Fischl fis...@nmr.mgh.harvard.edu
To: Maria Felber fel...@cbs.mpg.de
Cc: freesurfer@nmr.mgh.harvard.edu
Sent: Tuesday, September 13, 2011 4:07:55 PM
Subject: Re: [Freesurfer] Talairach transformation

Hi Maria

you can use tkregister2 to check the accuracy of the talairach.xfm
transform (xform for short), and correct it if you want.

cheers
Bruce
On Tue, 13 Sep 2011, Maria Felber wrote:


Hi Bruce,

thanks for the first response. I tried to find some information on the
webpage about xform, but failed. So what is xform standing for and
where/how can I check it?
As in the later processing stages I want to do localization and

DCM-Modeling with my data, I guess the correct talairach coords are kind
of
important for later comparisons.

Thanks again,
Maria

- Original Message -
From: Bruce Fischl fis...@nmr.mgh.harvard.edu
To: Maria Felber fel...@cbs.mpg.de
Cc: freesurfer@nmr.mgh.harvard.edu
Sent: Friday, September 9, 2011 2:13:05 PM
Subject: Re: [Freesurfer] Talairach transformation

Hi Maria

as long as the tal xform is reasonable I wouldn't worry about it, unless
for some reason you care a lot about the accuracy of the talairach
coords.

cheers
Bruce

p.s. not sure why it would be smaller

On Fri, 9 Sep 2011, Maria Felber wrote:



[Freesurfer] fieldsign-sess: ERROR Surf/src mismatch

2011-09-28 Thread Michelle Umali
Hey Doug and Freesurfers,
At the bottom is the output showing what steps didn't run.

1) Do you think I did the whole recon-all pipeline wrong? Here's what i did
after I originally ran recon-all -all -label_v1:

 I made edits with talairach registration edits with tkregister2 and  ran
recon-all -all -label_v1.
After that,with tkmedit  I made edits to brainmask.mgz and wm-mgz, then
recon-all -autorecon2-wm and autorecon 3, -label_v1.

 2) Was adding the -label_v1 flag what caused the below steps to not happen
and cause the mismatch?  Does adding the -label_v1 flag cause recon-all to
not run on the rest of the brain? If so, do I just run recon-all -autorecon2
and -autorecon3 without the -label_v1 flag?

Thanks.
Michelle

FreeSurfer:/media/sf_windows/
subjects recon-all -s ld07 -make all -dontrun
INFO: FreeSurfer build stamps do not match
Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.0.0
Current Stamp: freesurfer-Linux-centos4-stable-pub-v5.1.0
Subject 'ld07': make -n all
recon-all -s /media/sf_windows/subjects/ld07 -gcareg
recon-all -s /media/sf_windows/subjects/ld07 -canorm
recon-all -s /media/sf_windows/subjects/ld07 -careg -careginv
recon-all -s /media/sf_windows/subjects/ld07 -rmneck
recon-all -s /media/sf_windows/subjects/ld07 -skull-lta
recon-all -s /media/sf_windows/subjects/ld07 -calabel
recon-all -s /media/sf_windows/subjects/ld07 -normalization2
recon-all -s /media/sf_windows/subjects/ld07 -maskbfs
recon-all -s /media/sf_windows/subjects/ld07 -segmentation
recon-all -s /media/sf_windows/subjects/ld07 -fill
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -tessellate
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -tessellate
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -smooth1
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -smooth1
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate1
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate1
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -qsphere
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -qsphere
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -fix
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -fix
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -smooth2
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -smooth2
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate2
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate2
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate2
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate2
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -sphere
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -sphere
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -surfreg
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -surfreg
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -jacobian_white
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -jacobian_white
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -avgcurv
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -avgcurv
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -cortparc
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -cortparc
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -pial
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -pial
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -pial
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -pial
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -parcstats
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -parcstats
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -cortparc2
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -cortparc2
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -parcstats2
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -parcstats2
recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -cortribbon
recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -cortribbon
recon-all -s /media/sf_windows/subjects/ld07 -segstats
recon-all -s /media/sf_windows/subjects/ld07 -aparc2aseg
recon-all -s /media/sf_windows/subjects/ld07 -wmparc
- Hide quoted text -



On Wed, Sep 28, 2011 at 11:21 AM, Douglas N Greve gr...@nmr.mgh.harvard.edu
wrote:
 Hi Michelle, this almost surely means that the surfaces are out-of-synch.
 You can try
 recon-all -s subject -make all -dontrun
 on one of your subjects.

 If everything is in synch, then it should print
  make: Nothing to be done for `all'.

 If not, it should print out the steps that it would have run (if not for
the
 -dontrun option).

 doug

 Michelle Umali wrote:

 Hi Doug,
 I 

Re: [Freesurfer] Fwd: Talairach transformation

2011-09-28 Thread Nick Schmansky
you could also try:

-talairach -use-mritotal

which will use an alternate talarairch alignment scheme (from the MNI).
it sometimes works better (not necessary for 3T).

you should also probably add:

-nuintensitycor-3T

to the end of your recon-all command, which will run the nu_correct
stage optimized for 3T.  it wont help you with your talairach issue, but
will produce better results for 3T data downstream.

n.


On Wed, 2011-09-28 at 16:38 -0400, Bruce Fischl wrote:
 Hi Maria
 
 have you tried running without the talairach stuff? Try -notalairach and 
 see if it works for you
 
 cheers
 Bruce
 On Wed, 28 Sep 2011, Maria Felber wrote:
 
  Dear Ms. Kakunoori,
 
  sorry to bother you again, but as I did not get a reply to my last message 
  to everyone so far troubled with my question, I am trying here for a second 
  time.
  It is indeed the case, that all my data were scanned with a 3T. And if that 
  is indeed the problem Dr. Snyder figured out, then what can I do about it? 
  Or is anyone already working on this problem? I can hardly imagine I am the 
  only one recording with a 3T instead of a 1.5T.
  Yours sincerely,
  Maria Felber
 
  - Forwarded Message -
  From: Maria Felber fel...@cbs.mpg.de
  To: Avi Snyder a...@npg.wustl.edu
  Cc: Sita Kakunoori\, fel...@cbs.mpg.de, \Avi Snyder\ 
  a...@npg.wustl.edu, Bruce Fischl s...@nmr.mgh.harvard.edu, 
  freesurfer@nmr.mgh.harvard.edu
  Sent: Thursday, September 15, 2011 10:46:55 AM
  Subject: Re: [Freesurfer]  Talairach transformation
 
  Dear all,
 
  indeed all my T1-scans were recorded with a 3T scanner. So what can I do 
  about it or do you have something in progress which would fix this problem 
  anytime soon?
  Thanks,
  Maria
 
  - Original Message -
  From: Avi Snyder a...@npg.wustl.edu
  To: Sita Kakunoori s...@nmr.mgh.harvard.edu, fel...@cbs.mpg.de, Avi 
  Snyder a...@npg.wustl.edu
  Cc: Bruce Fischl fis...@nmr.mgh.harvard.edu
  Sent: Tuesday, September 13, 2011 11:03:28 PM
  Subject: Re: [Freesurfer]  Talairach transformation
 
  Hi Sita,
 
  Wrong-stretch (e.g., too fat or too thin) MP-RAGE atlas transforms are
  expected if the contrast properties of the sample image are far from those
  of the target. This condition can easily occur if the target is based on
  1.5T data and the sample is acquired at 3T. (3T but not 1.5T T1W images
  tend to be relatively bright in the center of the head.) Gd++ contrasted
  MP-RAGE scans routinely do not produce decent atlas transforms unless
  special measures are taken. A FreeSurfer fix for this problem is
  theoretically feasible.
 
  Avi
  ---
  On 9/13/11 2:26 PM, Sita Kakunoori s...@nmr.mgh.harvard.edu wrote:
 
  I might have seen this in a dataset. I am cc'ing Dr.Avi Anyder on this
  e-mail.
  Hi Dr.Snyder, Not sure if you remember but we saw something similar in a
  dataset here at the center where the talairach was much smaller than the
  orig.mgz volume and you created a new talairach template to be used with
  that dataset. I just wondered if this issue is similar to that.
 
  Thanks much,
  Sita.
  -- Forwarded message --
  Date: Tue, 13 Sep 2011 16:27:17 +0200 (CEST)
  From: Maria Felber fel...@cbs.mpg.de
  To: freesurfer@nmr.mgh.harvard.edu
  Subject: [Freesurfer]  Talairach transformation
 
  Hi Bruce,
 
  so we are back at the beginning. After I ran recon-all -all, I did
  exactly that and checked the xform using tkregister2. And here I always
  see that my talairach volume (the transform) is always smaller, which can
  be very well seen as the orig surfaces of the subjects are always a
  little outside the brain and reach well into the skull areas. Of course I
  can make the adjustments as descriped in the short instructions. But this
  also means I ran the recon-all precess anew for another 30 h per subject.
  And that is the reason, why I asked if this is normal that the tailarach
  transform is a) always smaller than the original brain, and b) if I can
  make any adjustments to prevent that from happening and thus saving
  another 30h per subject.
  In short: How acurate hat the talairach.xfm has to be and is it possible
  to change some parameters to make this transformation a little more
  accurate while running the recon-all process only once?
  Best,
  Maria
 
 
  - Original Message -
  From: Bruce Fischl fis...@nmr.mgh.harvard.edu
  To: Maria Felber fel...@cbs.mpg.de
  Cc: freesurfer@nmr.mgh.harvard.edu
  Sent: Tuesday, September 13, 2011 4:07:55 PM
  Subject: Re: [Freesurfer] Talairach transformation
 
  Hi Maria
 
  you can use tkregister2 to check the accuracy of the talairach.xfm
  transform (xform for short), and correct it if you want.
 
  cheers
  Bruce
  On Tue, 13 Sep 2011, Maria Felber wrote:
 
  Hi Bruce,
 
  thanks for the first response. I tried to find some information on the
  webpage about xform, but failed. So what is xform standing for and
  where/how can I check it?
  As in the 

[Freesurfer] Inclusion of lateral ventricle in pial surface

2011-09-28 Thread Vy Dinh
Dear Experts,

I noticed that the inferior horn of the lateral ventricles are not included 
within the pial surface while the posterior lateral ventricles are and wonder 
how one should go about when making corrections for the pial surface. This was 
observed in the subjects that I have worked with and also with the Freesurfer 
tutorial sample data. For the sample data, it appears that the hippocampus 
provides a clear delineation of the inferior and posterior lateral ventricles 
in the sagittal view (see attached image bert) which was not observed with 
our subjects (see attached images sub). The segmentation of the lateral 
ventricles, however, looks correct (by using the segmentation label function), 
so I am unsure if this discrepancy affects the measurements at all. However, it 
is worth confirming. I look forward to reading your responses.

Thank you very much,


Vy T.U. Dinh
Research Assistant, Neurological Sciences
Rush University Medical Center
Phone: (312) 563-3853
Fax: (312) 563-4660
Email: vy_d...@rush.edumailto:vy_d...@rush.edu
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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] Inclusion of lateral ventricle in pial surface

2011-09-28 Thread Bruce Fischl

Hi Vy,

no, it shouldn't. The pial surfaces are not trustworthy near the 
hippocampus, and we don't use them there.


Bruce
On Wed, 28 Sep 2011, Vy Dinh wrote:


Dear Experts,
I noticed that the inferior horn of the lateral ventricles are not included 
within the pial surface while the posterior lateral
ventricles are and wonder how one should go about when making corrections for 
the pial surface. This was observed in the subjects that
I have worked with and also with the Freesurfer tutorial sample data. For the 
sample data, it appears that the hippocampus provides a
clear delineation of the inferior and posterior lateral ventricles in the sagittal view 
(see attached image bert) which was not
observed with our subjects (see attached images sub). The segmentation of the 
lateral ventricles, however, looks correct (by using
the segmentation label function), so I am unsure if this discrepancy affects 
the measurements at all. However, it is worth confirming.
I look forward to reading your responses. 

Thank you very much,


Vy T.U. Dinh
Research Assistant, Neurological Sciences
Rush University Medical Center
Phone: (312) 563-3853
Fax: (312) 563-4660
Email: vy_d...@rush.edu

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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.


Re: [Freesurfer] fieldsign-sess: ERROR Surf/src mismatch

2011-09-28 Thread Douglas N Greve
The gcareg step depends on the talairach registration, so if that is 
changed, it thinks that the gcareg needs to change. If the gcareg needs 
to change, then the canorm needs to change, and so on. This does not 
mean that anything really needs to be updated. This is strictly looking 
at the time stamps and assuming that things have changed and need to be 
updated. If your results look ok, then there's no need to re-run.

Unfortunately, this does not tell us whether the surfaces themselves are 
up to date. You can do this with:
recon-all -vno-check -s subject
This looks at the number of vertices in each of the surfaces to make 
sure they are consistent.

doug


Michelle Umali wrote:
 Hey Doug and Freesurfers,
 At the bottom is the output showing what steps didn't run.

 1) Do you think I did the whole recon-all pipeline wrong? Here's what 
 i did after I originally ran recon-all -all -label_v1:

  I made edits with talairach registration edits with tkregister2 and  
 ran recon-all -all -label_v1. 
 After that,with tkmedit  I made edits to brainmask.mgz and wm-mgz, 
 then recon-all -autorecon2-wm and autorecon 3, -label_v1.

  2) Was adding the -label_v1 flag what caused the below steps to not 
 happen and cause the mismatch?  Does adding the -label_v1 flag cause 
 recon-all to not run on the rest of the brain? If so, do I just run 
 recon-all -autorecon2 and -autorecon3 without the -label_v1 flag?

 Thanks.
 Michelle

 FreeSurfer:/media/sf_windows/
 subjects recon-all -s ld07 -make all -dontrun
 INFO: FreeSurfer build stamps do not match
 Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.0.0
 Current Stamp: freesurfer-Linux-centos4-stable-pub-v5.1.0
 Subject 'ld07': make -n all
 recon-all -s /media/sf_windows/subjects/ld07 -gcareg
 recon-all -s /media/sf_windows/subjects/ld07 -canorm
 recon-all -s /media/sf_windows/subjects/ld07 -careg -careginv
 recon-all -s /media/sf_windows/subjects/ld07 -rmneck
 recon-all -s /media/sf_windows/subjects/ld07 -skull-lta
 recon-all -s /media/sf_windows/subjects/ld07 -calabel
 recon-all -s /media/sf_windows/subjects/ld07 -normalization2
 recon-all -s /media/sf_windows/subjects/ld07 -maskbfs
 recon-all -s /media/sf_windows/subjects/ld07 -segmentation
 recon-all -s /media/sf_windows/subjects/ld07 -fill
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -tessellate
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -tessellate
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -smooth1
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -smooth1
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate1
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate1
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -qsphere
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -qsphere
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -fix
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -fix
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -smooth2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -smooth2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -inflate2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -inflate2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -sphere
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -sphere
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -surfreg
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -surfreg
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -jacobian_white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -jacobian_white
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -avgcurv
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -avgcurv
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -cortparc
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -cortparc
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -pial
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -pial
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -pial
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -pial
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -parcstats
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -parcstats
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -cortparc2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -cortparc2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi lh -parcstats2
 recon-all -s /media/sf_windows/subjects/ld07 -hemi rh -parcstats2
 recon-all -s 

Re: [Freesurfer] fieldsign-sess: ERROR Surf/src mismatch

2011-09-28 Thread Michelle Umali
Hi Doug and Freesurfers,
I ran the -vno-check and the number of vertices matches for left and right
hemispheres (see below):

Since all there are an equal number of vertices, how is the mismatch error
occurring in fieldsign-sess and how do I get it to run?

Thanks for all your help.
Michelle

vno_match_check ld07 lh
Checking ld07/surf/lh.orig...
Checking ld07/surf/lh.white...
Checking ld07/surf/lh.pial...
Checking ld07/surf/lh.inflated...
Checking ld07/surf/lh.smoothwm...
Checking ld07/surf/lh.sphere...
Checking ld07/surf/lh.curv...
Checking ld07/surf/lh.sulc...
Checking ld07/surf/lh.area...
Checking ld07/surf/lh.thickness...
Checking ld07/label/lh.aparc.annot...
Checking ld07/label/lh.aparc.a2009s.annot...
Pass: all surfaces and surface data for subject ld07 have the same number of
vertices.

The same is true for the right hemisphere.




On Wed, Sep 28, 2011 at 5:21 PM, Douglas N Greve g r...@nmr.mgh.harvard.edu
 wrote:

 The gcareg step depends on the talairach registration, so if that is
 changed, it thinks that the gcareg needs to change. If the gcareg needs to
 change, then the canorm needs to change, and so on. This does not mean that
 anything really needs to be updated. This is strictly looking at the time
 stamps and assuming that things have changed and need to be updated. If your
 results look ok, then there's no need to re-run.

 Unfortunately, this does not tell us whether the surfaces themselves are up
 to date. You can do this with:
 recon-all -vno-check -s subject
 This looks at the number of vertices in each of the surfaces to make sure
 they are consistent.

 doug


 Michelle Umali wrote:

 Hey Doug and Freesurfers,
 At the bottom is the output showing what steps didn't run.

 1) Do you think I did the whole recon-all pipeline wrong? Here's what i
 did after I originally ran recon-all -all -label_v1:

  I made edits with talairach registration edits with tkregister2 and  ran
 recon-all -all -label_v1. After that,with tkmedit  I made edits to
 brainmask.mgz and wm-mgz, then recon-all -autorecon2-wm and autorecon 3,
 -label_v1.

  2) Was adding the -label_v1 flag what caused the below steps to not
 happen and cause the mismatch?  Does adding the -label_v1 flag cause
 recon-all to not run on the rest of the brain? If so, do I just run
 recon-all -autorecon2 and -autorecon3 without the -label_v1 flag?

 Thanks.
 Michelle

 FreeSurfer:/media/sf_windows/
 subjects recon-all -s ld07 -make all -dontrun
 INFO: FreeSurfer build stamps do not match
 Subject Stamp: freesurfer-Linux-centos4_x86_**64-stable-pub-v5.0.0
 Current Stamp: freesurfer-Linux-centos4-**stable-pub-v5.1.0
 Subject 'ld07': make -n all
 recon-all -s /media/sf_windows/subjects/**ld07 -gcareg
 recon-all -s /media/sf_windows/subjects/**ld07 -canorm
 recon-all -s /media/sf_windows/subjects/**ld07 -careg -careginv
 recon-all -s /media/sf_windows/subjects/**ld07 -rmneck
 recon-all -s /media/sf_windows/subjects/**ld07 -skull-lta
 recon-all -s /media/sf_windows/subjects/**ld07 -calabel
 recon-all -s /media/sf_windows/subjects/**ld07 -normalization2
 recon-all -s /media/sf_windows/subjects/**ld07 -maskbfs
 recon-all -s /media/sf_windows/subjects/**ld07 -segmentation
 recon-all -s /media/sf_windows/subjects/**ld07 -fill
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -tessellate
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -tessellate
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -smooth1
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -smooth1
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -inflate1
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -inflate1
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -qsphere
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -qsphere
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -fix
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -fix
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -white
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -smooth2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -smooth2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -inflate2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -inflate2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -inflate2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -inflate2
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -sphere
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -sphere
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi lh -surfreg
 recon-all -s /media/sf_windows/subjects/**ld07 -hemi rh -surfreg
 recon-all -s /media/sf_windows/subjects/**ld07 

Re: [Freesurfer] trac-all results

2011-09-28 Thread Ping-Hong Yeh
Hi Anastasia,

 I've tried both options, the choice 1 fixed some of the cases, but
not all; and the choice 2 did not work at all. Maybe I've missed
something here.

Few more questions:

1. Will the initial points have to include the points around start,
way, and end points of the tracts need to be segmented? Can I just
enter the points in the main stem of tracts?

2. Will EPI distortion correction, like using field map, in the
preprocessing steps help co-registration and thus improving the
labeling? So far more than 80% (4 out of 5 data sets) of the data
have at least one suboptimal tract, either in flt or bbr. (BTW, which
flag will call B0 fieldmaps (or phase and magnitude images) for
distortion correction? Do the fieldmap images need to be in the same
matrix size and resolution as DWI? )

3.  I wonder why these suboptimal segmented tracts are not terribly
off the white matter paths but just fewer voxels? Would the
probabilistic tractography implemented in FSL be good in working
around this problem by lowering the threshold for tract segmentation?

Thanks.

Ping

On Thu, Sep 22, 2011 at 1:18 PM, Anastasia Yendiki
ayend...@nmr.mgh.harvard.edu wrote:

 Hi Ping - There are 2 possibilities:

 1. You can try to fiddle with the initialization points yourself to make
 sure they're well in the CST. The point coordinates are saved in a text file
 - look at the --init argument of the dmri_paths command line, which you can
 find in trac-all.log.

 2. You can let trac-all select a different initialization by adding set
 reinit = 1 to your dmrirc file, then running trac-all -prior again.

 Once you change the initialization by doing either 1. or 2. above, you need
 to run trac-all -path to reconstruct this path again.

 You can change the pathlist in dmrirc to do only the path that failed.

 We jump through various hoops to make sure this sort of thing doesn't happen
 but in a few cases it can't be prevented, unfortunately.

 Let me know if this has helped or if you have any other questions!
 a.y

 On Thu, 22 Sep 2011, Ping-Hong Yeh wrote:

 Hi Anastasia,

 The both ends were not terribly off of the white matter, though the
 lower end was a bit off at the level of decussation. any suggestion in
 fixing this?

 Thanks.

 ping

 On Thu, Sep 22, 2011 at 12:51 PM, Anastasia Yendiki
 ayend...@nmr.mgh.harvard.edu wrote:

 Hi Ping - It looks like the path initialization may have failed. The
 algorithm needs an initial guess for the path and iterates from there.
 This
 initial guess is chosen based on the tracts in the atlas and if your
 subject
 is not perfectly aligned with the atlas this initial guess might end up
 going off the white matter for example. Does the blue line in your
 snapshot
 look like it may not coincide well with you subject's CST, going off the
 white matter close to the end, etc?

 a.y

 On Thu, 22 Sep 2011, Ping-Hong Yeh wrote:

 Hello,

 The segmented left CST tracts of one of our 3T data was not
 satisfactory, which has only few voxels with 1000 gray values (see
 attached snapshot pictures for trac-all and cst_prob). The
 manually tracking using deterministic tractography seems OK (see
 cst_stremline). Any suggestions on which step may go wrong in
 trac-all?

 Thank you,

 Ping



 The information in this e-mail is intended only for the person to whom it
 is
 addressed. If you believe this e-mail was sent to you in error and the
 e-mail
 contains patient information, please contact the Partners Compliance
 HelpLine at
 http://www.partners.org/complianceline . If the e-mail was sent to you in
 error
 but does not contain patient information, please contact the sender and
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Re: [Freesurfer] trac-all results

2011-09-28 Thread Anastasia Yendiki

Hi Ping - You can upload your data if you want me to take a look at it.

1. The initial points ideally should be along the midline of the pathway, 
starting from one end region of the pathway and going all the way to the 
other end region. (The default number is 5 control points but you can set 
ncpts = ... in your dmrirc to change that.)

2. You can look in $FREESURFER_HOME/bin/dmrirc.example for how to specify 
the field map inputs. They don't need to have the same matrix size and 
resolution as the DWIs.

3a. If it's the initialization that's failed, the output will just be the 
initial path and nothing else (which is I think what you mean by fewer 
voxels).

3b. The diffusion model used here is the same as the ball-and-stick model 
that FSL uses. If the threshold you're referring to is the minimum volume 
fraction for the anisotropic compartments of that model, you can set fmin 
= ... in your dmrirc to choose one.

I hope this helps a bit!
a.y

On Wed, 28 Sep 2011, Ping-Hong Yeh wrote:

 Hi Anastasia,

 I've tried both options, the choice 1 fixed some of the cases, but
 not all; and the choice 2 did not work at all. Maybe I've missed
 something here.

 Few more questions:

 1. Will the initial points have to include the points around start,
 way, and end points of the tracts need to be segmented? Can I just
 enter the points in the main stem of tracts?

 2. Will EPI distortion correction, like using field map, in the
 preprocessing steps help co-registration and thus improving the
 labeling? So far more than 80% (4 out of 5 data sets) of the data
 have at least one suboptimal tract, either in flt or bbr. (BTW, which
 flag will call B0 fieldmaps (or phase and magnitude images) for
 distortion correction? Do the fieldmap images need to be in the same
 matrix size and resolution as DWI? )

 3.  I wonder why these suboptimal segmented tracts are not terribly
 off the white matter paths but just fewer voxels? Would the
 probabilistic tractography implemented in FSL be good in working
 around this problem by lowering the threshold for tract segmentation?

 Thanks.

 Ping

 On Thu, Sep 22, 2011 at 1:18 PM, Anastasia Yendiki
 ayend...@nmr.mgh.harvard.edu wrote:

 Hi Ping - There are 2 possibilities:

 1. You can try to fiddle with the initialization points yourself to make
 sure they're well in the CST. The point coordinates are saved in a text file
 - look at the --init argument of the dmri_paths command line, which you can
 find in trac-all.log.

 2. You can let trac-all select a different initialization by adding set
 reinit = 1 to your dmrirc file, then running trac-all -prior again.

 Once you change the initialization by doing either 1. or 2. above, you need
 to run trac-all -path to reconstruct this path again.

 You can change the pathlist in dmrirc to do only the path that failed.

 We jump through various hoops to make sure this sort of thing doesn't happen
 but in a few cases it can't be prevented, unfortunately.

 Let me know if this has helped or if you have any other questions!
 a.y

 On Thu, 22 Sep 2011, Ping-Hong Yeh wrote:

 Hi Anastasia,

 The both ends were not terribly off of the white matter, though the
 lower end was a bit off at the level of decussation. any suggestion in
 fixing this?

 Thanks.

 ping

 On Thu, Sep 22, 2011 at 12:51 PM, Anastasia Yendiki
 ayend...@nmr.mgh.harvard.edu wrote:

 Hi Ping - It looks like the path initialization may have failed. The
 algorithm needs an initial guess for the path and iterates from there.
 This
 initial guess is chosen based on the tracts in the atlas and if your
 subject
 is not perfectly aligned with the atlas this initial guess might end up
 going off the white matter for example. Does the blue line in your
 snapshot
 look like it may not coincide well with you subject's CST, going off the
 white matter close to the end, etc?

 a.y

 On Thu, 22 Sep 2011, Ping-Hong Yeh wrote:

 Hello,

 The segmented left CST tracts of one of our 3T data was not
 satisfactory, which has only few voxels with 1000 gray values (see
 attached snapshot pictures for trac-all and cst_prob). The
 manually tracking using deterministic tractography seems OK (see
 cst_stremline). Any suggestions on which step may go wrong in
 trac-all?

 Thank you,

 Ping



 The information in this e-mail is intended only for the person to whom it
 is
 addressed. If you believe this e-mail was sent to you in error and the
 e-mail
 contains patient information, please contact the Partners Compliance
 HelpLine at
 http://www.partners.org/complianceline . If the e-mail was sent to you in
 error
 but does not contain patient information, please contact the sender and
 properly
 dispose of the e-mail.







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Re: [Freesurfer] Inclusion of lateral ventricle in pial surface

2011-09-28 Thread Vy Dinh
Thank you for the swift response Bruce. 


Vy T.U. Dinh
Research Assistant, Neurological Sciences
Rush University Medical Center
Phone: (312) 563-3853
Fax: (312) 563-4660
Email: vy_d...@rush.edu


From: Bruce Fischl [fis...@nmr.mgh.harvard.edu]
Sent: Wednesday, September 28, 2011 4:16 PM
To: Vy Dinh
Cc: freesurfer@nmr.mgh.harvard.edu; jennifer.g.gold...@gmail.com
Subject: Re: [Freesurfer] Inclusion of lateral ventricle in pial surface

Hi Vy,

no, it shouldn't. The pial surfaces are not trustworthy near the
hippocampus, and we don't use them there.

Bruce
On Wed, 28 Sep 2011, Vy Dinh wrote:

 Dear Experts,
 I noticed that the inferior horn of the lateral ventricles are not included 
 within the pial surface while the posterior lateral
 ventricles are and wonder how one should go about when making corrections for 
 the pial surface. This was observed in the subjects that
 I have worked with and also with the Freesurfer tutorial sample data. For the 
 sample data, it appears that the hippocampus provides a
 clear delineation of the inferior and posterior lateral ventricles in the 
 sagittal view (see attached image bert) which was not
 observed with our subjects (see attached images sub). The segmentation of 
 the lateral ventricles, however, looks correct (by using
 the segmentation label function), so I am unsure if this discrepancy affects 
 the measurements at all. However, it is worth confirming.
 I look forward to reading your responses.

 Thank you very much,


 Vy T.U. Dinh
 Research Assistant, Neurological Sciences
 Rush University Medical Center
 Phone: (312) 563-3853
 Fax: (312) 563-4660
 Email: vy_d...@rush.edu




The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
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Re: [Freesurfer] Mcsrch error during recon-all

2011-09-28 Thread Nick Schmansky
the log does not indicate that mri_em_register exited with an error.  it
appears that it produced its output correctly and continued through to
nearly the end of the stream.  the IFLAG messages can be ignored.

the log indicates that mri_label2label is exiting with an error when
trying to load the label from the fsaverage directory.  the fsaverage
subject is symlinked to the users SUBJECTS_DIR (to save space), but
sometimes this seems to cause problems on some systems.  i would try
copying it to your subjects dir:

cd $SUBJECTS_DIR
rm fsaverage
cp -r $FREESURFER_HOME/subjects/fsaverage .

then you just need to run the last two stages of recon-all:

recon-all -s subjid -balabels -label-exvivo-ec

or if you dont care about the Brodmann or exvivo EC labels, you dont
need to run anything.

for reference:
https://surfer.nmr.mgh.harvard.edu/fswiki/ReconAllDevTable

n.


On Wed, 2011-09-28 at 17:36 -0400, Warren Winter wrote:
 Hi Nick,
 
 
 Thanks for your help.
 
 
 The first set of errors (of the kind I described) follows the command
  mri_em_register -skull
 nu.mgz 
 /chb/freesurfer/x86_64-Linux/packages/freesurfer/dev/average/RB_all_withskull_2008-03-26.gca
  transforms/talairach_with_skull.lta 
 
 
 The next follows the command  mri_em_register -uns 3 -mask
 brainmask.mgz
 nu.mgz 
 /chb/freesurfer/x86_64-Linux/packages/freesurfer/dev/average/RB_all_2008-03-26.gca
  transforms/talairach.lta
 
 
 The next follows the command  mri_em_register -skull -t
 transforms/talairach.lta
 nu_noneck.mgz 
 /chb/freesurfer/x86_64-Linux/packages/freesurfer/dev/average/RB_all_withskull_2008-03-26.gca
  transforms/talairach_with_skull_2.lta 
 
 
 I've attached the log if you could use it for reference.
 
 
 Best,
 
 
 Warren
 
 
 
 
 
 On Sep 28, 2011, at 4:18 PM, Nick Schmansky wrote:
 
  the IFLAG messages can be ignored if mri_em_register is not exiting
  with
  error.  which command is running that is exiting with error?  can
  you
  send that command line from the recon-all.log file?
  
  n.
  
  On Wed, 2011-09-28 at 16:02 -0400, Warren Winter wrote:
   Hi,
   
   
   Each time I have run recon-all on our subjects, I end up with the
   same
   slew of error messages underneath Computing MAP estimate using [x
   number of] samples and underneath EM alignment process:
   
   
   IFLAG= -1  LINE SEARCH FAILED. SEE DOCUMENTATION OF ROUTINE
   MCSRCH
   ERROR RETURN OF LINE SEARCH: INFO= 3 POSSIBLE CAUSES: FUNCTION OR
   GRADIENT ARE INCORRECT OR INCORRECT TOLERANCES
   
   
   At the very end of the log file I see:
   
   
   Loading source label.
   Abort
   Linux rc-twice 2.6.39.2-mosix #1 SMP Wed Jun 29 11:53:08 EDT 2011
   x86_64 x86_64 x86_64 GNU/Linux
   
   
   recon-all -s 5 exited with ERRORS at Tue Sep 27 03:23:46 EDT 2011
   
   
   Any help on this would be greatly appreciated.
   
   
   Best,
   
   
   Warren
   
   --
   Warren Winter
   Lab Coordinator
   Children's Hospital Boston
   Division of Developmental Medicine
   1 Autumn Street, AU 650
   Boston, MA 02215
   857-218-5224
   
   
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  The information in this e-mail is intended only for the person to
  whom it is
  addressed. If you believe this e-mail was sent to you in error and
  the e-mail
  contains patient information, please contact the Partners Compliance
  HelpLine at
  http://www.partners.org/complianceline . If the e-mail was sent to
  you in error
  but does not contain patient information, please contact the sender
  and properly
  dispose of the e-mail.
  
  
 
 
 --
 Warren Winter
 Lab Coordinator
 Children's Hospital Boston
 Division of Developmental Medicine
 1 Autumn Street, AU 650
 Boston, MA 02215
 857-218-5224
 
 

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Re: [Freesurfer] TRACULA: how to implement DTI repeat sequence?

2011-09-28 Thread Ansgar Furst
Hi Anastasia,
Thanks so much for your message. You were right about the recon directory,
the contents had been accidentally moved elsewhere (sorry!) and once I moved
them back and reran the script everything worked like a charm without any
errors. However, it looks like I'm now stuck at the next processing stage
(fsl's bedpostX). I pasted the output with the error message below. FYI: I'm
unfortunately forced to run the bedpostX on a single Linux box (64-bit dual
core with 8GB of RAM) which I hope is OK?
Thanks so much for all your help,

Ansgar

==
trac-all -bedp -c scripts/dmrirc_single_subject_1only
INFO: SUBJECTS_DIR is /home/ajfurst/Data/WRIISC
INFO: Diffusion root is /home/ajfurst/Data/WRIISC/TRACULA
Actual FREESURFER_HOME /usr/local/freesurfer
ln -sf
/home/ajfurst/Data/WRIISC/TRACULA/015/dlabel/diff/anat_brain_mask.bbr.nii.gz
/home/ajfurst/Data/WRIISC/TRACULA/015/dmri/nodif_brain_mask.nii.gz
ln -sf /home/ajfurst/Data/WRIISC/TRACULA/015/dmri/dwi.nii.gz
/home/ajfurst/Data/WRIISC/TRACULA/015/dmri/data.nii.gz
WARN: Running FSL's bedbost locally - this might take a while
WARN: It is recommended to run this step on a cluster
bedpostx_seychelles /home/ajfurst/Data/WRIISC/TRACULA/015/dmri
subjectdir is /home/ajfurst/Data/WRIISC/TRACULA/015/dmri
Making bedpostx directory structure
Queuing preprocessing stages
Queuing parallel processing stage
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Re: [Freesurfer] TRACULA: how to implement DTI repeat sequence?

2011-09-28 Thread Anastasia Yendiki

Hi Ansgar - Most likely everything is fine. Sometimes the script that's 
built into bedpost to monitor its progress gives this error but in fact 
everything has ran fine. You should check that all the outputs are there 
in the dmri.bedpostX directory. See for list of bedpost output files:
http://www.fmrib.ox.ac.uk/fsl/fdt/fdt_bedpostx.html

a.y

On Wed, 28 Sep 2011, Ansgar Furst wrote:

 Hi Anastasia,
 Thanks so much for your message. You were right about the recon directory, the
 contents had been accidentally moved elsewhere (sorry!) and once I moved them
 back and reran the script everything worked like a charm without any errors.
 However, it looks like I'm now stuck at the next processing stage (fsl's
 bedpostX). I pasted the output with the error message below. FYI: I'm
 unfortunately forced to run the bedpostX on a single Linux box (64-bit dual 
 core
 with 8GB of RAM) which I hope is OK?
 Thanks so much for all your help,
 
 Ansgar
 
 ==
 trac-all -bedp -c scripts/dmrirc_single_subject_1only
 INFO: SUBJECTS_DIR is /home/ajfurst/Data/WRIISC
 INFO: Diffusion root is /home/ajfurst/Data/WRIISC/TRACULA
 Actual FREESURFER_HOME /usr/local/freesurfer
 ln -sf
 /home/ajfurst/Data/WRIISC/TRACULA/015/dlabel/diff/anat_brain_mask.bbr.nii.gz
 /home/ajfurst/Data/WRIISC/TRACULA/015/dmri/nodif_brain_mask.nii.gz
 ln -sf /home/ajfurst/Data/WRIISC/TRACULA/015/dmri/dwi.nii.gz
 /home/ajfurst/Data/WRIISC/TRACULA/015/dmri/data.nii.gz
 WARN: Running FSL's bedbost locally - this might take a while
 WARN: It is recommended to run this step on a cluster
 bedpostx_seychelles /home/ajfurst/Data/WRIISC/TRACULA/015/dmri
 subjectdir is /home/ajfurst/Data/WRIISC/TRACULA/015/dmri
 Making bedpostx directory structure
 Queuing preprocessing stages
 Queuing parallel processing stage
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[Freesurfer] aseg2feat and aparc2feat

2011-09-28 Thread Michelle Umali
Dear Freesurfers,
I wanted to generate binary masks for areas found in the Freesurfer Color
Lookup Table.
For  example, I wanted to use number 433, the Visual_V3d_l.  I tried to use

aseg2feat -feat featdir --aseg aparc+aseg
fslmaths -featdir/reg/freesurfer/aparc+aseg.nii.gz -thr 433v uthr 433 \
 featdir/reg/freesurfer/Visual_V3d_l.nii.gz

The resulting image was empty.  I was able to use aseg2feat for all
subcortical regions, so then i used aparc2feat. However, this uses a
different color table which is missing many of the regions present in the
Freesurfer Color Lookup table that I would like to use.

How can I get area 433 (Visual_V3d_l) from the Freesurfer Color Lookup Table
so I can later run fslmaths to generate a mask?

Thanks.
Michelle
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