Re: [Freesurfer] Probably activation due to vessels

2012-10-16 Thread Jörg Pfannmöller
Hi Doug,

the analysis is done on the cortex surface. The following commands are used for 
the analysis of the functional activation in the right hemisphere cortex:

preproc-sess -s sessionID -fsd bold -nostc -surface fsaverage lhrh -mni305 
-fwhm 0 -per-run -nosmooth

plot-twf-sess   -s sessionID -fsd bold -mc 

tkregister-sess -s sessionID -fsd bold -per-run -bbr-sum

mkanalysis-sess -fsd bold -surface fsaverage rh -fwhm 0 -event-related 
-paradigm stim.par -nconditions 1 -spmhrf 0 -TR 2 -refeventdur 10 -nskip 5 
-polyfit 2 -analysis stim.sm0.rh -force

mkcontrast-sess -analysis  stim.sm0.rh -contrast stim-li-v-base -a 1

selxavg3-sess -s sessionID -analysis stim.sm0.rh -no-preproc

tksurfer-sess -s sessionID -analysis stim.sm0.rh -c stim-li-v-base -tcl 
./label_01.tcl.

Left hemisphere and sub-cortical analysis are also carried out. Results are 
depicted on the flatted cortex surface in the primary somatosensory cortex. 
This label is a combination of the freesurfer areas BA1, BA2, BA3a and BA3b. 
The activation is masked to this label. An example of the line like pattern 
is uploaded on your ftp server using my email (pfannmoelj ... 
uni-greifswald.de, the at sign is replaced by dots) as the password. There is a 
snaking 
line in the middle of the image which is a candidate for a vessel. In other 
images the straight line like patterns or line like patterns with gaps are 
found. Is there a way to analyze the data in a volume based stream without 
differentiation between cortex and sub-cortical brain in which the distance 
of the line like pattern relative to the gray substance is visible? This could 
be used in order to classify between true activation and vessel activation. 
We have epi data with spatial resolution of 2x2x4mm^3 (used to generate 
attached image) and 1.5x1.5x2mm^3 which both show line like patterns. 
Structural 
data are taken using the single echo freesurfer protocol for the flash 
sequence, recommended for cortex. I hope those information are of help.  
 
Sincerely yours 

   pfannmoe


On Mon, 15 Oct 2012 17:52:04 -0400
Douglas N Greve gr...@nmr.mgh.harvard.edu wrote:

 Hi Jorg, can you tell us a little more? A picture would be good. Also, 
 describe how you have done your analysis (eg, on the surface or in the 
 volume, how much smoothing).
 doug
 
 On 10/15/2012 11:01 AM, wrote:
  Dear Freesurfers,
 
  I computed the functional activation in a sensory task using freesurfer's 
  fsfast stream. In the cortex surface line like activated regions are 
  present. Their extension is much larger than the extension of the expected 
  regions. Therefore, I suppose that those regions are due to vessels. Is 
  there a possibility in freesurfer to remove them. Ideally there would be 
  something like a volume based mode which does not sxclude the cortex. In 
  this mode the vessels couls be identified and removed. Any help is highly 
  apprexiated.
 
  Respectfully yours
 
  pfannmoe
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[Freesurfer] error measuring LGI

2012-10-16 Thread Gabriel Gonzalez Escamilla
Dear FS experts I'm trying to run the recon-all -s subjid -localGI in both terminal and matlab, and neither of them is working.I'm using currently version of FS and matlab R2009b.the following error alwais apair:INFO: FreeSurfer build stamps do not matchSubject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjectsActual FREESURFER_HOME /root/trabajo/freesurfer-rwxr-xr-x  1 root root 6867734 Oct 16 15:23 /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.logLinux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux/root/trabajo/freesurfer/subjects/c_Macarena/surf##@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012 mris_compute_lgi --i lh.pialERROR: Matlab is required to run mris_compute_lgi!Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linuxrecon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012Matlab exist on the  startup.m file as:% FreeSurfer -%fshome = getenv('FREESURFER_HOME');fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome);path(path,fsmatlab);clear fshome fsmatlab;%-%Can anyone help me on this?Best Regards,Gabriel
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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Marie Schaer
Gabriel,

If I am correct, your path (fsmatlab) is pointing to the matlab folder of 
freesurfer distribution (I.e. Including the matlab scripts) whereas it should 
point to the matlab installation directory.

You can check using the command getmatlab.

Let me know,

Marie

On 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es wrote:

 Dear FS experts 
 
 I'm trying to run the recon-all -s subjid -localGI in both terminal and 
 matlab, and neither of them is working.
 I'm using currently version of FS and matlab R2009b.
 
 the following error alwais apair:
 
 INFO: FreeSurfer build stamps do not match
 Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0
 Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0
 INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects
 Actual FREESURFER_HOME /root/trabajo/freesurfer
 -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 
 /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log
 Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 
 x86_64 x86_64 x86_64 GNU/Linux
 /root/trabajo/freesurfer/subjects/c_Macarena/surf
 #
 #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012
 
  mris_compute_lgi --i lh.pial
 
 ERROR: Matlab is required to run mris_compute_lgi!
 Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 
 x86_64 x86_64 x86_64 GNU/Linux
 
 recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012
 
 
 
 
 Matlab exist on the  startup.m file as:
 
 % FreeSurfer -%
 fshome = getenv('FREESURFER_HOME');
 fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome);
 path(path,fsmatlab);
 clear fshome fsmatlab;
 %-%
 
 
 Can anyone help me on this?
 
 Best Regards,
 Gabriel
 
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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Gabriel Gonzalez Escamilla
Thanks Marie,You are right is pointing to the FSmatlab directory not to the installation folder, but the  wiki say so:You will also need $FREESURFER_HOME/matlab in your matlab path set up in your ~/matlab/starup.m script. Do I need to change that in the startup.m?I did also try the getmatlab command and said that matlab does not exist, I'm guessing this is the problem.Bests,GabrielEl 16/10/12, Marie Schaer  marie.sch...@unige.ch escribió:Gabriel,If I am correct, your path (fsmatlab) is pointing to the matlab folder of freesurfer distribution (I.e. Including the matlab scripts) whereas it should point to the matlab installation directory.You can check using the command getmatlab.Let me know,MarieOn 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es wrote: Dear FS experts   I'm trying to run the recon-all -s subjid -localGI in both terminal and matlab, and neither of them is working. I'm using currently version of FS and matlab R2009b.  the following error alwais apair:  INFO: FreeSurfer build stamps do not match Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0 Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0 INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects Actual FREESURFER_HOME /root/trabajo/freesurfer -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux /root/trabajo/freesurfer/subjects/c_Macarena/surf # #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012   mris_compute_lgi --i lh.pial  ERROR: Matlab is required to run mris_compute_lgi! Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux  recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012 Matlab exist on the  startup.m file as:  % FreeSurfer -% fshome = getenv('FREESURFER_HOME'); fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome); path(path,fsmatlab); clear fshome fsmatlab; %-%   Can anyone help me on this?  Best Regards, Gabriel  ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer   The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.___Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer-- --PhD. student Gabriel González-EscamillaLaboratory of Functional NeuroscienceDepartment of Physiology, Anatomy, and Cell BiologyUniversity Pablo de OlavideCtra. de Utrera, Km.141013 - Seville- Spain -Email: ggon...@upo.eshttp://www.upo.es/neuroaging/es/
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[Freesurfer] pctsurfcon question

2012-10-16 Thread Phil Greer
I do not have a question on how to use the program, the wiki covered that well.

My question is about the formula embedded in the program to calculate the 
contrast. 

The formula is ((wm-gm)/((wm+gm)/2))*100

This creates a dynamic range of -200 to +200. Which the last time I checked is 
not really a percent as the command name implies. 

Was there some reasoning behind this that I am missing?

Phil Greer
University of Pittsburgh
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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Gabriel Gonzalez Escamilla
Dear Marie,I've tried to set the matlab installation path, into the tcsh path (where my FS_HOME is), but It's not working. I have no idea how to change this on the startup.m, can you help me with it?Regards,GabrielEl 16/10/12, Marie Schaer  marie.sch...@unige.ch escribió:Gabriel,If I am correct, your path (fsmatlab) is pointing to the matlab folder of freesurfer distribution (I.e. Including the matlab scripts) whereas it should point to the matlab installation directory.You can check using the command getmatlab.Let me know,MarieOn 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es wrote: Dear FS experts   I'm trying to run the recon-all -s subjid -localGI in both terminal and matlab, and neither of them is working. I'm using currently version of FS and matlab R2009b.  the following error alwais apair:  INFO: FreeSurfer build stamps do not match Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0 Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0 INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects Actual FREESURFER_HOME /root/trabajo/freesurfer -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux /root/trabajo/freesurfer/subjects/c_Macarena/surf # #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012   mris_compute_lgi --i lh.pial  ERROR: Matlab is required to run mris_compute_lgi! Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux  recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012 Matlab exist on the  startup.m file as:  % FreeSurfer -% fshome = getenv('FREESURFER_HOME'); fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome); path(path,fsmatlab); clear fshome fsmatlab; %-%   Can anyone help me on this?  Best Regards, Gabriel  ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer   The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.___Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer-- --PhD. student Gabriel González-EscamillaLaboratory of Functional NeuroscienceDepartment of Physiology, Anatomy, and Cell BiologyUniversity Pablo de OlavideCtra. de Utrera, Km.141013 - Seville- Spain -Email: ggon...@upo.eshttp://www.upo.es/neuroaging/es/
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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Marie Schaer
Gabriel,

I would start by adding the path to the matlab installation directory to $PATH. 
On a Mac it looks like /Applications/Matlab_R*/bin. Then the getmatlab command 
should work, and LGI as well.

Marie

On 16 oct. 2012, at 16:39, Gabriel Gonzalez Escamilla ggon...@upo.es wrote:

 Thanks Marie,
 
 You are right is pointing to the FSmatlab directory not to the installation 
 folder, but the  wiki say so:
 
 You will also need $FREESURFER_HOME/matlab in your matlab path set up in 
 your ~/matlab/starup.m script. 
 
 Do I need to change that in the startup.m?
 I did also try the getmatlab command and said that matlab does not exist, I'm 
 guessing this is the problem.
 
 Bests,
 Gabriel
 
 
 El 16/10/12, Marie Schaer marie.sch...@unige.ch escribió:
 
 Gabriel,
 
 If I am correct, your path (fsmatlab) is pointing to the matlab folder of 
 freesurfer distribution (I.e. Including the matlab scripts) whereas it 
 should point to the matlab installation directory.
 
 You can check using the command getmatlab.
 
 Let me know,
 
 Marie
 
 On 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es wrote:
 
  Dear FS experts 
  
  I'm trying to run the recon-all -s subjid -localGI in both terminal and 
  matlab, and neither of them is working.
  I'm using currently version of FS and matlab R2009b.
  
  the following error alwais apair:
  
  INFO: FreeSurfer build stamps do not match
  Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0
  Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0
  INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects
  Actual FREESURFER_HOME /root/trabajo/freesurfer
  -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 
  /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log
  Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 
  2006 x86_64 x86_64 x86_64 GNU/Linux
  /root/trabajo/freesurfer/subjects/c_Macarena/surf
  #
  #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012
  
   mris_compute_lgi --i lh.pial
  
  ERROR: Matlab is required to run mris_compute_lgi!
  Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 
  2006 x86_64 x86_64 x86_64 GNU/Linux
  
  recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012
  
  
  
  
  Matlab exist on the  startup.m file as:
  
  % FreeSurfer -%
  fshome = getenv('FREESURFER_HOME');
  fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome);
  path(path,fsmatlab);
  clear fshome fsmatlab;
  %-%
  
  
  Can anyone help me on this?
  
  Best Regards,
  Gabriel
  
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  is
  addressed. If you believe this e-mail was sent to you in error and the 
  e-mail
  contains patient information, please contact the Partners Compliance 
  HelpLine at
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 -- 
 --
 PhD. student Gabriel González-Escamilla
 Laboratory of Functional Neuroscience
 Department of Physiology, Anatomy, and Cell Biology
 University Pablo de Olavide
 Ctra. de Utrera, Km.1
 41013 - Seville
 - Spain -
 
 Email: ggon...@upo.es
 http://www.upo.es/neuroaging/es/
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Re: [Freesurfer] pctsurfcon question

2012-10-16 Thread Douglas N Greve

Yes, that was actually a mistake on my part. It does go between -200 and 
+200.
doug



On 10/16/2012 11:02 AM, Phil Greer wrote:
 I do not have a question on how to use the program, the wiki covered that 
 well.

 My question is about the formula embedded in the program to calculate the 
 contrast.

 The formula is ((wm-gm)/((wm+gm)/2))*100

 This creates a dynamic range of -200 to +200. Which the last time I checked 
 is not really a percent as the command name implies.

 Was there some reasoning behind this that I am missing?

 Phil Greer
 University of Pittsburgh
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MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Gabriel Gonzalez Escamilla
Marie,I'm working on centOS 4, I'd add the path to the matlab installation folder on my PATH as:setenv MATLABPATH /root/trabajo/matlab2009
setenv PATH ${MATLABPATH}/bin:${PATH}And this is not working stillAny ideas?GabrielEl 16/10/12, Marie Schaer  marie.sch...@unige.ch escribió:Gabriel,I would start by adding the path to the matlab installation directory to $PATH. On a Mac it looks like /Applications/Matlab_R*/bin. Then the getmatlab command should work, and LGI as well.MarieOn 16 oct. 2012, at 16:39, Gabriel Gonzalez Escamilla ggon...@upo.es ggon...@upo.es wrote:Thanks Marie,You are right is pointing to the FSmatlab directory not to the installation folder, but the  wiki say so:You will also need $FREESURFER_HOME/matlab in your matlab path set up in your ~/matlab/starup.m script. Do I need to change that in the startup.m?I did also try the getmatlab command and said that matlab does not exist, I'm guessing this is the problem.Bests,GabrielEl 16/10/12, Marie Schaer  marie.sch...@unige.ch marie.sch...@unige.ch escribió:Gabriel,If I am correct, your path (fsmatlab) is pointing to the matlab folder of freesurfer distribution (I.e. Including the matlab scripts) whereas it should point to the matlab installation directory.You can check using the command getmatlab.Let me know,MarieOn 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es ggon...@upo.es wrote: Dear FS experts   I'm trying to run the recon-all -s subjid -localGI in both terminal and matlab, and neither of them is working. I'm using currently version of FS and matlab R2009b.  the following error alwais apair:  INFO: FreeSurfer build stamps do not match Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0 Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0 INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects Actual FREESURFER_HOME /root/trabajo/freesurfer -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux /root/trabajo/freesurfer/subjects/c_Macarena/surf # #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012   mris_compute_lgi --i lh.pial  ERROR: Matlab is required to run mris_compute_lgi! Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 2006 x86_64 x86_64 x86_64 GNU/Linux  recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 2012 Matlab exist on the  startup.m file as:  % FreeSurfer -% fshome = getenv('FREESURFER_HOME'); fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome); path(path,fsmatlab); clear fshome fsmatlab; %-%   Can anyone help me on this?  Best Regards, Gabriel  ___ Freesurfer mailing list  Freesurfer@nmr.mgh.harvard.eduFreesurfer@nmr.mgh.harvard.edu Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer   The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.___Freesurfer mailing listFreesurfer@nmr.mgh.harvard.edu Freesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer-- --PhD. student Gabriel González-EscamillaLaboratory of Functional NeuroscienceDepartment of Physiology, Anatomy, and Cell BiologyUniversity Pablo de OlavideCtra. de Utrera, Km.141013 - Seville- Spain -Email:  ggon...@upo.esggon...@upo.es ggon...@upo.eshttp://www.upo.es/neuroaging/es/
-- --PhD. student Gabriel González-EscamillaLaboratory of Functional NeuroscienceDepartment of Physiology, Anatomy, and Cell BiologyUniversity Pablo de OlavideCtra. de Utrera, Km.141013 - Seville- Spain -Email: ggon...@upo.eshttp://www.upo.es/neuroaging/es/
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Re: [Freesurfer] error measuring LGI

2012-10-16 Thread Marie Schaer

... Strange, then I would just quickly look at the following things (in a new 
terminal, so that you are sure that everything is cleanly set): 

1) whether the $PATH is indeed correctly set without typo. Either by verifying 
the $PATH variable (type $PATH in your shell, you should see your full path to 
matlab). Or by just prompting the command matlab in your shell, which should 
open a matlab session.

2) I would source the freesurfer environment variables again (set the 
FREESURFER_HOME variable and then source SetUpFreeSurfer.csh), and check 
whether getmatlab give you the location of your matlab command (something like 
/root/trabajo/matlab2009/bin/matlab)

Given that I am not a centOS specialist, if this doesn't work, we should maybe 
ask someone else, like e.g. Nick if he has a better idea.

Let me know,

Marie


On Oct 16, 2012, at 6:54 PM, Gabriel Gonzalez Escamilla wrote:

 Marie,
 
 I'm working on centOS 4, I'd add the path to the matlab installation folder 
 on my PATH as:
 setenv MATLABPATH /root/trabajo/matlab2009
 setenv PATH ${MATLABPATH}/bin:${PATH}
 
 And this is not working still
 Any ideas?
 
 Gabriel
 
 
 El 16/10/12, Marie Schaer marie.sch...@unige.ch escribió:
 
 
 
 Gabriel,
 
 I would start by adding the path to the matlab installation directory to 
 $PATH. On a Mac it looks like /Applications/Matlab_R*/bin. Then the 
 getmatlab command should work, and LGI as well.
 
 Marie
 
 On 16 oct. 2012, at 16:39, Gabriel Gonzalez Escamilla ggon...@upo.es 
 ggon...@upo.es wrote:
 
 
 Thanks Marie,
 
 You are right is pointing to the FSmatlab directory not to the installation 
 folder, but the  wiki say so:
 
 You will also need $FREESURFER_HOME/matlab in your matlab path set up in 
 your ~/matlab/starup.m script. 
 
 Do I need to change that in the startup.m?
 I did also try the getmatlab command and said that matlab does not exist, 
 I'm guessing this is the problem.
 
 Bests,
 Gabriel
 
 
 El 16/10/12, Marie Schaer marie.sch...@unige.ch marie.sch...@unige.ch 
 escribió:
 
 Gabriel,
 
 If I am correct, your path (fsmatlab) is pointing to the matlab folder of 
 freesurfer distribution (I.e. Including the matlab scripts) whereas it 
 should point to the matlab installation directory.
 
 You can check using the command getmatlab.
 
 Let me know,
 
 Marie
 
 On 16 oct. 2012, at 16:02, Gabriel Gonzalez Escamilla ggon...@upo.es 
 ggon...@upo.es wrote:
 
  Dear FS experts 
  
  I'm trying to run the recon-all -s subjid -localGI in both terminal 
  and matlab, and neither of them is working.
  I'm using currently version of FS and matlab R2009b.
  
  the following error alwais apair:
  
  INFO: FreeSurfer build stamps do not match
  Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v4.2.0
  Current Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.1.0
  INFO: SUBJECTS_DIR is /root/trabajo/freesurfer/subjects
  Actual FREESURFER_HOME /root/trabajo/freesurfer
  -rwxr-xr-x  1 root root 6867734 Oct 16 15:23 
  /root/trabajo/freesurfer/subjects/c_Macarena/scripts/recon-all.log
  Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 
  2006 x86_64 x86_64 x86_64 GNU/Linux
  /root/trabajo/freesurfer/subjects/c_Macarena/surf
  #
  #@# Local Gyrification Index lh Tue Oct 16 15:24:31 CEST 2012
  
   mris_compute_lgi --i lh.pial
  
  ERROR: Matlab is required to run mris_compute_lgi!
  Linux localhost.localdomain 2.6.9-34.ELsmp #1 SMP Thu Mar 9 06:23:23 GMT 
  2006 x86_64 x86_64 x86_64 GNU/Linux
  
  recon-all -s c_Macarena exited with ERRORS at Tue Oct 16 15:24:31 CEST 
  2012
  
  
  
  
  Matlab exist on the  startup.m file as:
  
  % FreeSurfer -%
  fshome = getenv('FREESURFER_HOME');
  fsmatlab = sprintf('%s/root/trabajo/freesurfer/matlab',fshome);
  path(path,fsmatlab);
  clear fshome fsmatlab;
  %-%
  
  
  Can anyone help me on this?
  
  Best Regards,
  Gabriel
  
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  The information in this e-mail is intended only for the person to whom 
  it is
  addressed. If you believe this e-mail was sent to you in error and the 
  e-mail
  contains patient information, please contact the Partners Compliance 
  HelpLine at
  http://www.partners.org/complianceline . If the e-mail was sent to you 
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 -- 
 --
 PhD. student Gabriel González-Escamilla
 Laboratory of Functional 

Re: [Freesurfer] Mixed-effects models for longitudinal data analysis in Freesurfer

2012-10-16 Thread Douglas N Greve
If you want to do a repeated measures ANOVA with more than two time 
points, I've put a page together here:

http://surfer.nmr.mgh.harvard.edu/fswiki/RepeatedMeasuresAnova

doug


On 10/15/2012 08:24 PM, Harry Hallock [hhal5...@uni.sydney.edu.au] wrote:
 Hi Martin,

 If you could make available that lme toolbox link, that would be great!
 Thanks for the help.

 Cheers,
 Harry
 
 *From:* jorge luis [jbernal0...@yahoo.es]
 *Sent:* Tuesday, 16 October 2012 8:16 AM
 *To:* Martin Reuter; Harry Hallock [hhal5...@uni.sydney.edu.au]
 *Cc:* freesurfer@nmr.mgh.harvard.edu
 *Subject:* Mixed-effects models for longitudinal data analysis in 
 Freesurfer

 Hi Harry

 As Martin said, longitudinal linear mixed-effects models (lme) are the 
 recommended tool for analyzing longitudinal data obtained from the 
 Freesurfer longitudinal image processing pipeline. The increase in 
 power can be dramatic. Coming up there is a paper about this subject. 
 We are working on making our lme tools available and easy to use but 
 in the mean time, if you are interested, I can make available a link 
 for you to download our Matlab-based lme toolbox.

 Best
 -Jorge


 
 *De:* Martin Reuter mreu...@nmr.mgh.harvard.edu
 *Para:* Harry Hallock hhal5...@uni.sydney.edu.au; Douglas N
 Greve gr...@nmr.mgh.harvard.edu;
 freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edu
 *Enviado:* Domingo 14 de octubre de 2012 21:06
 *Asunto:* Re: [Freesurfer] 3 Factor glm group analysis

 Hi Harry.

 I have some scripts to compute a slope into the time thickness or
 volume (linear fits) and then run a standard glm on that .

 However, we recommend to run a linear mixed effects model
 (external software). We are working on making that available.

 Best Martin

 Harry Hallock hhal5...@uni.sydney.edu.au wrote:

 Thanks Doug!

 If i wanted to add a third time-point, what would u suggest would be 
 a good method to use for time x group interaction?

 Harry
 
 

 From: freesurfer-boun...@nmr.mgh.harvard.edu 
 [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
 [gr...@nmr.mgh.harvard.edu]
 Sent: Wednesday, 10 October 2012 1:10 AM
 To: freesurfer@nmr.mgh.harvard.edu
 Subject: Re: [Freesurfer] 3 Factor glm group analysis

 Hi Harry, I would do a time1-time2 subtraction (fscalc) and then do a 
 2
 group analysis (search for paired on our wiki).
 doug



 On 10/09/2012 12:45 AM, hhal5...@uni.sydney.edu.au wrote:

 Hello, We are currently doing a longitudinal Group
 Analysis using FreeSurfer, and were wondering if there is
 a way to run a 3 factor design (time is 2 levels, group is
 2 levels, subject is 10 levels) using the mri_glmfit
 model, as i want to test the time by group interaction? Is
 there a way of writing this model in an FSDG file? If we
 can't do this using mri_glmfit, is it possible to do this
 using QDEC? Regards, Harry
 
 
 Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


 --
 Douglas N. Greve, Ph.D.
 MGH-NMR Center
 gr...@nmr.mgh.harvard.edu
 Phone Number: 617-724-2358
 Fax: 617-726-7422

 Bugs:surfer.nmr.mgh.harvard.edu/fswiki/BugReporting  
 http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
 FileDrop:www.nmr.mgh.harvard.edu/facility/filedrop/index.html  
 http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html

 
 

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 The information in this e-mail is intended only for the person to 
 whom it is
 addressed. If you believe this e-mail was sent to you in error and 
 the e-mail
 contains patient information, please contact the Partners Compliance 
 HelpLine at
 http://www.partners.org/complianceline  . If the e-mail was sent to 
 you in error
 but does not contain patient information, please contact the sender 
 and properly
 dispose of the e-mail.




 
 

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   mailing list
 Freesurfer@nmr.mgh.harvard.edu
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer



 -- 
 Sent from my phone, please excuse brevity.

 

[Freesurfer] DODS and group age interaction

2012-10-16 Thread Mahinda Yogarajah
Dear Experts,

I have 2 groups - controls (22 subjects) and patients (19 subjects) with mean 
ages that are not significantly different, though ranges/median are. I want to 
compare cortical thickness between groups while allowing for age (age as 
nuisance factor) but also want to see if there is an interaction between age 
and group (age as continuous variable). I have demeaned the age across both 
controls and patients and then used qdec. 

1) Using DODS and demeaned ages I find that there is an age-gp interaction such 
that patients have quicker thickness decline with age than controls. This 
survives FDR 0.05 and monte carlo VWP 0.005 CWP 0.05. Is this finding valid 
given that I used demeaned ages (rather than absolute ages) to look for 
interaction or does it make  no difference ?

2) When I come to look to see whether there is a gp difference in thickness I 
enter age as a nuisance variable in qdec (as opposed to continuous variable 
above) and use DODS with demeaned age variable across gp. Am I safe to 
interpret my findings normally given age-gp interaction or is is not safe - if 
it is not safe how can I look for gp differences or it ok to interpret results 
provided gp differences are not in regions where I see an interaction ?

Thanks.

Mahinda



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[Freesurfer] Installation difficulties (Mac)

2012-10-16 Thread Julia Nantes
I have downloaded the FreeSurfer software onto a Mac computer.

I did the setenv/source steps and got this output:

Setting up environment for FreeSurfer/FS-FAST (and FSL)
FREESURFER_HOME   /Applications/freesurfer/
FSFAST_HOME   /Applications/freesurfer//fsfast
FSF_OUTPUT_FORMAT nii.gz
SUBJECTS_DIR  /Applications/freesurfer//subjects
MNI_DIR   /Applications/freesurfer//mni

Next, I obtained a license and finally got the text to go into a pico .license 
file after doing this:

[Lisa-Koskis-iMac:~] rsussex% sudo -s
Password:
[Lisa-Koskis-iMac:~] root# cd /Applications/freesurfer/
[Lisa-Koskis-iMac:/Applications/freesurfer] root# pico $FREESURFER_HOME .license
FREESURFER_HOME: Undefined variable.
[Lisa-Koskis-iMac:/Applications/freesurfer] root# pico .license
[Lisa-Koskis-iMac:/Applications/freesurfer] root# ls
ASegStatsLUT.txtSetUpFreeSurfer.sh  fsfast
AUTHORS Simple_surface_labels2009.txt   lib
DefectLUT.txt   VERSION matlab
FreeSurferColorLUT.txt  WMParcStatsLUT.txt  mni
FreeSurferEnv.csh   average sessions
FreeSurferEnv.shbin subjects
LICENSE build-stamp.txt 
tkmeditParcColorsCMA
NOTICE  datatktools
README  diffusion   trctrain
SegmentNoLUT.txtdocs
SetUpFreeSurfer.csh fsafd
[Lisa-Koskis-iMac:/Applications/freesurfer] root# cd ../..
[Lisa-Koskis-iMac:/] root# cd /Applications/freesurfer//subjects/
[Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# ls
README  bertfsaverage   fsaverage4  fsaverage6  
rh.EC_average   sample-002.mgz
V1_average  cvs_avg35   fsaverage3  fsaverage5  lh.EC_average   
sample-001.mgz
[Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# tkmedit bert orig.mgz
tkmedit: Command not found.
[Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# qdec
qdec: Command not found.

Since the 'Testing your FreeSurfer installation commands from the wiki page 
are not working, I may not have installed this properly.

Any insights as to how this could be resolved would be much appreciated.

Thank you,
Julia

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Re: [Freesurfer] Installation difficulties (Mac)

2012-10-16 Thread Louis Nicholas Vinke
Hi Julia,
I'm not certain, but I think you just need to define FREESURFER_HOME 
source FS again before trying to run tkmedit or qdec.  The pico 
$FREESURFER_HOME .license command resulted in FREESURFER_HOME: Undefined 
variable., so that environment variable needs to be set.  I think after 
the sudo command you were then logged in as root and so the previous 
environment variables were not carried over.
-Louis


On Tue, 16 Oct 2012, Julia Nantes wrote:

 I have downloaded the FreeSurfer software onto a Mac computer.

 I did the setenv/source steps and got this output:

 Setting up environment for FreeSurfer/FS-FAST (and FSL)
 FREESURFER_HOME   /Applications/freesurfer/
 FSFAST_HOME   /Applications/freesurfer//fsfast
 FSF_OUTPUT_FORMAT nii.gz
 SUBJECTS_DIR  /Applications/freesurfer//subjects
 MNI_DIR   /Applications/freesurfer//mni

 Next, I obtained a license and finally got the text to go into a pico 
 .license file after doing this:

 [Lisa-Koskis-iMac:~] rsussex% sudo -s
 Password:
 [Lisa-Koskis-iMac:~] root# cd /Applications/freesurfer/
 [Lisa-Koskis-iMac:/Applications/freesurfer] root# pico $FREESURFER_HOME 
 .license
 FREESURFER_HOME: Undefined variable.
 [Lisa-Koskis-iMac:/Applications/freesurfer] root# pico .license
 [Lisa-Koskis-iMac:/Applications/freesurfer] root# ls
 ASegStatsLUT.txtSetUpFreeSurfer.sh  fsfast
 AUTHORS Simple_surface_labels2009.txt   lib
 DefectLUT.txt   VERSION matlab
 FreeSurferColorLUT.txt  WMParcStatsLUT.txt  mni
 FreeSurferEnv.csh   average sessions
 FreeSurferEnv.shbin subjects
 LICENSE build-stamp.txt 
 tkmeditParcColorsCMA
 NOTICE  datatktools
 README  diffusion   trctrain
 SegmentNoLUT.txtdocs
 SetUpFreeSurfer.csh fsafd
 [Lisa-Koskis-iMac:/Applications/freesurfer] root# cd ../..
 [Lisa-Koskis-iMac:/] root# cd /Applications/freesurfer//subjects/
 [Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# ls
 README  bertfsaverage   fsaverage4  fsaverage6
   rh.EC_average   sample-002.mgz
 V1_average  cvs_avg35   fsaverage3  fsaverage5  lh.EC_average 
   sample-001.mgz
 [Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# tkmedit bert 
 orig.mgz
 tkmedit: Command not found.
 [Lisa-Koskis-iMac:/Applications/freesurfer/subjects] root# qdec
 qdec: Command not found.

 Since the 'Testing your FreeSurfer installation commands from the wiki page 
 are not working, I may not have installed this properly.

 Any insights as to how this could be resolved would be much appreciated.

 Thank you,
 Julia

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Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future

2012-10-16 Thread Joshua Lee
Hi Everyone,

Back in May I was very excited to learn that there was some movement toward
allowing Freesurfer to utilize the higher than 1mm iso. resolutions of some
of our structural images, which could be fantastic help in subcortical
segmentations. Is this something that is still in the works for the next
release?

gratefully,

Joshua




-
Joshua Lee
Graduate Student
Center for Mind and Brain 
Department of Psychology
University of California, Davis
530.747.3805


On Thu, May 31, 2012 at 5:49 PM, Bruce Fischl fis...@nmr.mgh.harvard.eduwrote:

 Hi Joshua

 sorry, I haven't found the time to really work on it. I spent a couple of
 hours and found some problems, but haven't found the time to fix them

 Bruce

 On Thu, 31 May 2012, Joshua Lee wrote:

  Hi Bruce,

 I'm just checking in to see how it turned out with the subcortical
 segmentation using the high resolution images I sent.
 Best,

 Joshua






 -
 Joshua Lee
 Graduate Student
 Center for Mind and Brain 
 Department of Psychology
 University of California, Davis
 530.747.3805


 On Tue, May 15, 2012 at 5:29 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu
 
 wrote:
  you need to call mris_make_surfaces directly. It's a bit
  complicated as you need to intensity normalize and register the
  hires volume to the surfaces first. I have an example script if
  anyone is interested, but no one has used it yet but me I don't
  think (unless Matt Glasser has gotten his version working, which
  on second thought he probably has)

  On Mon, 14 May 2012, Michael Waskom wrote:

Hi Bruce,
Is there a flag for this on recon-all? áOr do you

need to use
mri_make_surfaces directly?

Best,
Michael

On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl
fis...@nmr.mgh.harvard.edu
wrote:
á á áHi Joshua

á á áyes, we already have upgraded
mris_make_surfaces to take higher
á á áres data
á á áand refine the surfaces with it. Haven't tried
it on the aseg
á á áyet, but if
á á áyou upload a sample dataset I could see how
hard it is.

á á ácheers
á á áBruce
á á áOn Mon, 14 May 2012,
á á áJoshua Lee wrote:

á á á Dear Freesurfers,
á á á
á á á Over the last years, MR imaging technology
hasimproved such
á á áthat sub 1-mm
á á á isotropic scans can be obtained with good
signal to noise
á á ácharacteristics.
á á á For example, our lab uses 0.7mm isotropic
structural MR
á á áimages. I understand
á á á that the Freesurfer pipeline will up-sample
these to 1mm
á á áisotropic, but it
á á á seems a shame that so much information is
left unused which
á á ácould be used to
á á á improve the accuracy of sub-cortical and
cortical
á á ásegmentation. My question
á á á is whether there are any plans at Freesurfer
to change the
á á áreference
á á á standard resolution from 1mm isotropic, or
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technology.
á á á
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Re: [Freesurfer] DODS and group age interaction

2012-10-16 Thread Douglas N Greve


On 10/16/2012 02:08 PM, Mahinda Yogarajah wrote:
 Dear Experts,

 I have 2 groups - controls (22 subjects) and patients (19 subjects) with mean 
 ages that are not significantly different, though ranges/median are. I want 
 to compare cortical thickness between groups while allowing for age (age as 
 nuisance factor) but also want to see if there is an interaction between age 
 and group (age as continuous variable). I have demeaned the age across both 
 controls and patients and then used qdec.

 1) Using DODS and demeaned ages I find that there is an age-gp interaction 
 such that patients have quicker thickness decline with age than controls. 
 This survives FDR 0.05 and monte carlo VWP 0.005 CWP 0.05. Is this finding 
 valid given that I used demeaned ages (rather than absolute ages) to look for 
 interaction or does it make  no difference ?
For this contrast (group-slope interaction), it makes no difference.

 2) When I come to look to see whether there is a gp difference in thickness I 
 enter age as a nuisance variable in qdec (as opposed to continuous variable 
 above) and use DODS with demeaned age variable across gp. Am I safe to 
 interpret my findings normally given age-gp interaction or is is not safe - 
 if it is not safe how can I look for gp differences or it ok to interpret 
 results provided gp differences are not in regions where I see an interaction 
 ?
It is not safe. If there is an interaction, then the difference between 
groups changes with age. You can think of it as two thickness vs age 
lines, one for each group. If there is no interaction, then these lines 
will be parallel, meaning that the difference between the groups will be 
the same no matter what age. If there is an interaction, these lines 
will not be parallel, meaning that the group difference changes with 
age, and so whether you see a difference between them or not depends on 
what age you test them at. Without demeaning, this test age will be 
age=0. If you demean, then the age will be age=mean(age).

doug

 Thanks.

 Mahinda



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Re: [Freesurfer] Probably activation due to vessels

2012-10-16 Thread Douglas N Greve
can you send a pic?


On 10/16/2012 05:44 AM, Jörg Pfannmöller wrote:
 Hi Doug,

 the analysis is done on the cortex surface. The following commands are used 
 for the analysis of the functional activation in the right hemisphere cortex:

 preproc-sess -s sessionID -fsd bold -nostc -surface fsaverage lhrh -mni305 
 -fwhm 0 -per-run -nosmooth

 plot-twf-sess   -s sessionID -fsd bold -mc

 tkregister-sess -s sessionID -fsd bold -per-run -bbr-sum

 mkanalysis-sess -fsd bold -surface fsaverage rh -fwhm 0 -event-related 
 -paradigm stim.par -nconditions 1 -spmhrf 0 -TR 2 -refeventdur 10 -nskip 5 
 -polyfit 2 -analysis stim.sm0.rh -force

 mkcontrast-sess -analysis  stim.sm0.rh -contrast stim-li-v-base -a 1

 selxavg3-sess -s sessionID -analysis stim.sm0.rh -no-preproc

 tksurfer-sess -s sessionID -analysis stim.sm0.rh -c stim-li-v-base -tcl 
 ./label_01.tcl.

 Left hemisphere and sub-cortical analysis are also carried out. Results are 
 depicted on the flatted cortex surface in the primary somatosensory cortex.
 This label is a combination of the freesurfer areas BA1, BA2, BA3a and BA3b. 
 The activation is masked to this label. An example of the line like pattern
 is uploaded on your ftp server using my email (pfannmoelj ... 
 uni-greifswald.de, the at sign is replaced by dots) as the password. There is 
 a snaking
 line in the middle of the image which is a candidate for a vessel. In other 
 images the straight line like patterns or line like patterns with gaps are
 found. Is there a way to analyze the data in a volume based stream without 
 differentiation between cortex and sub-cortical brain in which the distance
 of the line like pattern relative to the gray substance is visible? This 
 could be used in order to classify between true activation and vessel 
 activation.
 We have epi data with spatial resolution of 2x2x4mm^3 (used to generate 
 attached image) and 1.5x1.5x2mm^3 which both show line like patterns. 
 Structural
 data are taken using the single echo freesurfer protocol for the flash 
 sequence, recommended for cortex. I hope those information are of help.

 Sincerely yours

 pfannmoe


 On Mon, 15 Oct 2012 17:52:04 -0400
 Douglas N Grevegr...@nmr.mgh.harvard.edu  wrote:

 Hi Jorg, can you tell us a little more? A picture would be good. Also,
 describe how you have done your analysis (eg, on the surface or in the
 volume, how much smoothing).
 doug

 On 10/15/2012 11:01 AM, wrote:
 Dear Freesurfers,

 I computed the functional activation in a sensory task using freesurfer's 
 fsfast stream. In the cortex surface line like activated regions are 
 present. Their extension is much larger than the extension of the expected 
 regions. Therefore, I suppose that those regions are due to vessels. Is 
 there a possibility in freesurfer to remove them. Ideally there would be 
 something like a volume based mode which does not sxclude the cortex. In 
 this mode the vessels couls be identified and removed. Any help is highly 
 apprexiated.

 Respectfully yours

  pfannmoe
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Re: [Freesurfer] Control point edits adversely affect cortical surfaces using FS 5.1

2012-10-16 Thread Vanessa Louise Cropley
Thank-you Bruce!


On 16/10/12 12:25 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote:

 Hi Vanessa 
 I'm running some tests now
 Bruce
 
 
 
 On Oct 15, 2012, at 9:10 PM, Vanessa Louise Cropley vcrop...@unimelb.edu.au
 wrote:
 
 Dear Bruce/freesurfer community,
 
 Thank-you for offering to take a look at our data.
 
 I have uploaded two files to the ftp. They are called Subject_Before_CP.zip
 and Subject_After_Cpedit.zip. Please let me know if you haven't received
 them. I uploaded these last Friday but haven't as yet had a reply.
 
 I did this as a test as I assumed that a single ctrl point in WM would have
 no effect on the surfaces. The 1 ctrl point was added to the LH WM in
 temporal cortex (slice 120).
 
 Thank-you for your help, it would be great if we could find a solution to
 this problem.
 
 - Vanessa
 
 
 On 12/10/12 1:24 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote:
 
 Hi Vanessa
 
 if you can upload an example (the entire subject dir) before adding the
 single control point you refer to, and after adding it we'll track it down.
 
 thanks
 Bruce
 
 
 
 On Thu, 11 Oct 2012, Vanessa Louise Cropley wrote:
 
 Hi all,
 
 I have seen others post a similar problem on the freesurfer mailing list
 but
 I could not find a solution.
 
 When I edit a volume using control points, I am noticing that the use of CP
 edits adversely effects the wm/gm surfaces in the resulting re-processed
 image. Like others have reported, the surfaces are adversely affected in
 locations distant from the CP edits. The temporal lobes are particularly
 affected.
 
 We are using freesurfer 5.1.
 I have noticed the following things:
 
 1. The problem occurs irrespective of the number of control points added,
i.e. whether 100 or 10 control points added
 2. The problem occurred when only one CP was added in a voxel that was
clearly wm
 3. The problem did not occur after reprocessing with FS 4.5
 4. I have tried the flag to disable mri_ca_normalize when reprocessing with
?autorecon2. This did not seem to help. I used the command: recon-all
?nocanorm ?autorecon2-cp ?subjid $SUBJ
 
 I have screenshots available that illustrate the changes in the surfaces
 after reprocessing.
 
 Could anyone help with this problem?
 
 Thank-you,
 
 Vanessa
 
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Re: [Freesurfer] DODS and group age interaction

2012-10-16 Thread MAHINDA YOGARAJAH
Dear Doug, 

Many thanks for reply.  Given the age-group interaction, and the fact that even 
when age is demeaned it simply means a difference in thickness will be tested 
for at age=mean age (as opposed to age=0) can I at least interpret the findings 
when using DODS model with age as a nuisance factor by saying that the 
difference in thickness between groups represents the difference between groups 
at the mean age across both groups.

Beyond that limited interpretation, is there any other way to analyse the data 
? Is there a another model I could use ? My age-group interactions are in a 
different location to the group differences - does this make any interpretation 
of group differences more robust ?

Thanks.

Mahinda


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Re: [Freesurfer] DODS and group age interaction

2012-10-16 Thread Douglas Greve

On 10/16/12 8:27 PM, MAHINDA YOGARAJAH wrote:
 Dear Doug,

 Many thanks for reply.  Given the age-group interaction, and the fact that 
 even when age is demeaned it simply means a difference in thickness will be 
 tested for at age=mean age (as opposed to age=0) can I at least interpret the 
 findings when using DODS model with age as a nuisance factor by saying that 
 the difference in thickness between groups represents the difference between 
 groups at the mean age across both groups.
Yes.

 Beyond that limited interpretation, is there any other way to analyse the 
 data ? Is there a another model I could use ? My age-group interactions are 
 in a different location to the group differences - does this make any 
 interpretation of group differences more robust ?
You can reanalyze using DOSS and look for group differences. If those 
differences are in a different location than the interaction, then you 
are good to go.
doug

 Thanks.

 Mahinda




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