Re: [MBZ] Coronavirus Vaccine

2020-03-14 Thread Andrew Strasfogel via Mercedes
SO maybe we should do the same?

On Fri, Mar 13, 2020 at 10:59 PM G Mann via Mercedes 
wrote:

> Chinese: It is amazing what you can do when there are NO EPA, FDA, safety
> controls, and human life is conveniently expendable for the communist good,
> as dictated by those in power...
>
> "Testing,, we don't need no stinking testing... we try it and that's the
> test. We have to many people anyway, so no one will miss a few thousand if
> it doesn't work..."
>
> On Fri, Mar 13, 2020 at 5:17 PM archer75--- via Mercedes <
> mercedes@okiebenz.com> wrote:
>
> > Chinese say they have had preliminary success with a combination of an
> > anti-malarial drug and drugs that have successfully suppressed AIDS.
> > Gerry
> > ...
> > On Fri, 13 Mar 2020 19:06:47 + (UTC)
> > Max Dillon via Mercedes  wrote:
> >
> > > Looks like some companies think they've already got a vaccine ready for
> > testing.
> > >
> > >
> >
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
> > >
> > >
> > > Max Dillon
> > > Charleston SC
> > >
> > > Mar 13, 2020 12:24:51 PM archer75--- via Mercedes <
> mercedes@okiebenz.com
> > >:
> > >
> > > >
> > > >
> > > >
> > > > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> > > >
> > > >
> > > > At a White House news conference Tuesday, Anthony Fauci, the head of
> > the National Institute of Allergy and Infectious Disease, told President
> > Donald Trump a coronavirus vaccine would likely not be available within
> the
> > next year or two. Trump responded: “I like the sound of a couple of
> months
> > better.”
> > > >
> > > > But a vaccine is not going to be available in the next couple of
> > months, and according to Dr. Paul Offit, that’s appropriate. Offit,
> > director of the Vaccine Education Center at Children’s Hospital of
> > Philadelphia, is the co-developer of the rotavirus vaccine. It took
> roughly
> > 26 years to perfect that protection against a disease that, according to
> > the Centers for Disease Control and Prevention, was the leading cause for
> > severe diarrhea in children before the vaccine’s introduction in 2006.
> > > >
> > > > Why is it unrealistic to expect a vaccine for coronavirus in a few
> > months?
> > > >
> > > > Nobody’s ever seen this virus before. Therefore, if you’re interested
> > in making a vaccine, you first had access to that virus only a couple
> > months ago. That’s not long.
> > > >
> > > > [To make a vaccine] you first need to make a decision as to what
> > approach you want to take. Then you have to do extensive animal model
> > testing to make sure that the approach that you’ve taken is safe in
> > animals, and that it induces an immune response which would likely be
> > protective. Then you gradually do studies in people to make sure it’s
> safe,
> > and then to make sure that it induces an immune response. That takes
> time,
> > a lot of time, typically years. Then and only then, are you ready to put
> it
> > into people to see whether or not it works in an outbreak situation.
> > > >
> > > > In 2018, after the World Health Organization declared an Ebola
> > outbreak in the Democratic Republic of Congo, there was an experimental
> > vaccine very quickly.
> > > >
> > > > I think people got fooled by Ebola. When the outbreak occurred in
> West
> > Africa and we had a vaccine pretty much that rolled off shelf within
> weeks,
> > people thought, Ha! That’s easy.
> > > >
> > > > But what they didn’t realize is people have been working on an Ebola
> > vaccine for 20 years. They’ve done the animal model testing. They’ve done
> > the testing to make sure that the vaccine was safe and was immunogenic.
> > > >
> > > > But that’s not true here. This is a new virus. So we’re starting from
> > scratch.
> > > >
> > > > What is it about this virus that makes people confident that a
> vaccine
> > will be available?
> > > >
> > > > I don’t know. You know, I’d say about 15% to 20% of the respiratory
> > infections that we see in our hospital in the winter months are [types
> of]
> > coronavirus. This is a virus that has been around for 50 years.
> > > >
> > > > But here are these three newer strains of coronavirus — MERS, SARS,
> > and now this COVID-19. The first two viruses, SARS and MERS, have come
> and
> > gone.
> > > >
> > > > I think this [COVID-19] virus likely will come back because it’s
> > different. If you were infected with SARS or MERS viruses, you were sick.
> > And it’s very easy to tell who was sick and who wasn’t. You could then
> > quarantine those people — put a moat around them, if you will — so that
> > they wouldn’t infect others. So those infections quickly died out. This
> > virus is more like flu. It spreads in a similar manner to flu by
> > respiratory droplet. It’s about as contagious as flu. It has the same set
> > of symptoms as flu. And I think in the end, frankly, it’s going to have
> the
> > same 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread G Mann via Mercedes
Chinese: It is amazing what you can do when there are NO EPA, FDA, safety
controls, and human life is conveniently expendable for the communist good,
as dictated by those in power...

"Testing,, we don't need no stinking testing... we try it and that's the
test. We have to many people anyway, so no one will miss a few thousand if
it doesn't work..."

On Fri, Mar 13, 2020 at 5:17 PM archer75--- via Mercedes <
mercedes@okiebenz.com> wrote:

> Chinese say they have had preliminary success with a combination of an
> anti-malarial drug and drugs that have successfully suppressed AIDS.
> Gerry
> ...
> On Fri, 13 Mar 2020 19:06:47 + (UTC)
> Max Dillon via Mercedes  wrote:
>
> > Looks like some companies think they've already got a vaccine ready for
> testing.
> >
> >
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
> >
> >
> > Max Dillon
> > Charleston SC
> >
> > Mar 13, 2020 12:24:51 PM archer75--- via Mercedes  >:
> >
> > >
> > >
> > >
> > > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> > >
> > >
> > > At a White House news conference Tuesday, Anthony Fauci, the head of
> the National Institute of Allergy and Infectious Disease, told President
> Donald Trump a coronavirus vaccine would likely not be available within the
> next year or two. Trump responded: “I like the sound of a couple of months
> better.”
> > >
> > > But a vaccine is not going to be available in the next couple of
> months, and according to Dr. Paul Offit, that’s appropriate. Offit,
> director of the Vaccine Education Center at Children’s Hospital of
> Philadelphia, is the co-developer of the rotavirus vaccine. It took roughly
> 26 years to perfect that protection against a disease that, according to
> the Centers for Disease Control and Prevention, was the leading cause for
> severe diarrhea in children before the vaccine’s introduction in 2006.
> > >
> > > Why is it unrealistic to expect a vaccine for coronavirus in a few
> months?
> > >
> > > Nobody’s ever seen this virus before. Therefore, if you’re interested
> in making a vaccine, you first had access to that virus only a couple
> months ago. That’s not long.
> > >
> > > [To make a vaccine] you first need to make a decision as to what
> approach you want to take. Then you have to do extensive animal model
> testing to make sure that the approach that you’ve taken is safe in
> animals, and that it induces an immune response which would likely be
> protective. Then you gradually do studies in people to make sure it’s safe,
> and then to make sure that it induces an immune response. That takes time,
> a lot of time, typically years. Then and only then, are you ready to put it
> into people to see whether or not it works in an outbreak situation.
> > >
> > > In 2018, after the World Health Organization declared an Ebola
> outbreak in the Democratic Republic of Congo, there was an experimental
> vaccine very quickly.
> > >
> > > I think people got fooled by Ebola. When the outbreak occurred in West
> Africa and we had a vaccine pretty much that rolled off shelf within weeks,
> people thought, Ha! That’s easy.
> > >
> > > But what they didn’t realize is people have been working on an Ebola
> vaccine for 20 years. They’ve done the animal model testing. They’ve done
> the testing to make sure that the vaccine was safe and was immunogenic.
> > >
> > > But that’s not true here. This is a new virus. So we’re starting from
> scratch.
> > >
> > > What is it about this virus that makes people confident that a vaccine
> will be available?
> > >
> > > I don’t know. You know, I’d say about 15% to 20% of the respiratory
> infections that we see in our hospital in the winter months are [types of]
> coronavirus. This is a virus that has been around for 50 years.
> > >
> > > But here are these three newer strains of coronavirus — MERS, SARS,
> and now this COVID-19. The first two viruses, SARS and MERS, have come and
> gone.
> > >
> > > I think this [COVID-19] virus likely will come back because it’s
> different. If you were infected with SARS or MERS viruses, you were sick.
> And it’s very easy to tell who was sick and who wasn’t. You could then
> quarantine those people — put a moat around them, if you will — so that
> they wouldn’t infect others. So those infections quickly died out. This
> virus is more like flu. It spreads in a similar manner to flu by
> respiratory droplet. It’s about as contagious as flu. It has the same set
> of symptoms as flu. And I think in the end, frankly, it’s going to have the
> same mortality rate as flu.
> > >
> > > There are certainly human studies showing that if you’re infected with
> a coronavirus — meaning one of the typical coronaviruses — you can have
> immunity to that strain for at least a year and probably longer. That’s
> encouraging. If natural infection can protect you, then it’s encouraging
> that it can produce an 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread archer75--- via Mercedes
Chinese say they have had preliminary success with a combination of an 
anti-malarial drug and drugs that have successfully suppressed AIDS.
Gerry 
...
On Fri, 13 Mar 2020 19:06:47 + (UTC)
Max Dillon via Mercedes  wrote:

> Looks like some companies think they've already got a vaccine ready for 
> testing.
> 
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
> 
> 
> Max Dillon
> Charleston SC
> 
> Mar 13, 2020 12:24:51 PM archer75--- via Mercedes :
> 
> > 
> > 
> > 
> > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> > 
> > 
> > At a White House news conference Tuesday, Anthony Fauci, the head of the 
> > National Institute of Allergy and Infectious Disease, told President Donald 
> > Trump a coronavirus vaccine would likely not be available within the next 
> > year or two. Trump responded: “I like the sound of a couple of months 
> > better.”
> > 
> > But a vaccine is not going to be available in the next couple of months, 
> > and according to Dr. Paul Offit, that’s appropriate. Offit, director of the 
> > Vaccine Education Center at Children’s Hospital of Philadelphia, is the 
> > co-developer of the rotavirus vaccine. It took roughly 26 years to perfect 
> > that protection against a disease that, according to the Centers for 
> > Disease Control and Prevention, was the leading cause for severe diarrhea 
> > in children before the vaccine’s introduction in 2006.
> > 
> > Why is it unrealistic to expect a vaccine for coronavirus in a few months?
> > 
> > Nobody’s ever seen this virus before. Therefore, if you’re interested in 
> > making a vaccine, you first had access to that virus only a couple months 
> > ago. That’s not long.
> > 
> > [To make a vaccine] you first need to make a decision as to what approach 
> > you want to take. Then you have to do extensive animal model testing to 
> > make sure that the approach that you’ve taken is safe in animals, and that 
> > it induces an immune response which would likely be protective. Then you 
> > gradually do studies in people to make sure it’s safe, and then to make 
> > sure that it induces an immune response. That takes time, a lot of time, 
> > typically years. Then and only then, are you ready to put it into people to 
> > see whether or not it works in an outbreak situation.
> > 
> > In 2018, after the World Health Organization declared an Ebola outbreak in 
> > the Democratic Republic of Congo, there was an experimental vaccine very 
> > quickly.
> > 
> > I think people got fooled by Ebola. When the outbreak occurred in West 
> > Africa and we had a vaccine pretty much that rolled off shelf within weeks, 
> > people thought, Ha! That’s easy.
> > 
> > But what they didn’t realize is people have been working on an Ebola 
> > vaccine for 20 years. They’ve done the animal model testing. They’ve done 
> > the testing to make sure that the vaccine was safe and was immunogenic.
> > 
> > But that’s not true here. This is a new virus. So we’re starting from 
> > scratch.
> > 
> > What is it about this virus that makes people confident that a vaccine will 
> > be available?
> > 
> > I don’t know. You know, I’d say about 15% to 20% of the respiratory 
> > infections that we see in our hospital in the winter months are [types of] 
> > coronavirus. This is a virus that has been around for 50 years.
> > 
> > But here are these three newer strains of coronavirus — MERS, SARS, and now 
> > this COVID-19. The first two viruses, SARS and MERS, have come and gone.
> > 
> > I think this [COVID-19] virus likely will come back because it’s different. 
> > If you were infected with SARS or MERS viruses, you were sick. And it’s 
> > very easy to tell who was sick and who wasn’t. You could then quarantine 
> > those people — put a moat around them, if you will — so that they wouldn’t 
> > infect others. So those infections quickly died out. This virus is more 
> > like flu. It spreads in a similar manner to flu by respiratory droplet. 
> > It’s about as contagious as flu. It has the same set of symptoms as flu. 
> > And I think in the end, frankly, it’s going to have the same mortality rate 
> > as flu.
> > 
> > There are certainly human studies showing that if you’re infected with a 
> > coronavirus — meaning one of the typical coronaviruses — you can have 
> > immunity to that strain for at least a year and probably longer. That’s 
> > encouraging. If natural infection can protect you, then it’s encouraging 
> > that it can produce an immune response which is protective and which you 
> > should be able to mimic with vaccination.
> > 
> > Vaccine development is tightly regulated. How much of that is about safety 
> > vs. red tape?
> > 
> > If you’re going to be testing this in otherwise healthy people who are 
> > very, very unlikely to die from this infection, you better make sure it’s 
> > safe. So you want those 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Greg Fiorentino via Mercedes
I saw an interview of someone from a company that says they have a potential 
vaccine. They explained that it is NOT a vaccine that works by causing an 
immune response, but that it is the actual antibodies themselves, that your 
body would have produced. The production of these antibodies is (I suppose) 
CRISPR'd into some single-cell organism, then cultured in mass quantities. 
Safety is of course still an issue; but someone would not catch the disease 
itself from the vaccine. 

Also, it would be a treatment as well as a preventive. The hope is that this 
process could be tested and brought to market more quickly than the usual 
vaccine process.

Greg

-Original Message-
From: Mercedes [mailto:mercedes-boun...@okiebenz.com] On Behalf Of archer75--- 
via Mercedes
Sent: Friday, March 13, 2020 9:24 AM
To: Mercedes Discussion List
Cc: arche...@embarqmail.com
Subject: [MBZ] Coronavirus Vaccine




Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q


At a White House news conference Tuesday, Anthony Fauci, the head of the 
National Institute of Allergy and Infectious Disease, told President Donald 
Trump a coronavirus vaccine would likely not be available within the next year 
or two. Trump responded: “I like the sound of a couple of months better.”

But a vaccine is not going to be available in the next couple of months, and 
according to Dr. Paul Offit, that’s appropriate. Offit, director of the Vaccine 
Education Center at Children’s Hospital of Philadelphia, is the co-developer of 
the rotavirus vaccine. It took roughly 26 years to perfect that protection 
against a disease that, according to the Centers for Disease Control and 
Prevention, was the leading cause for severe diarrhea in children before the 
vaccine’s introduction in 2006.

Why is it unrealistic to expect a vaccine for coronavirus in a few months?

Nobody’s ever seen this virus before. Therefore, if you’re interested in making 
a vaccine, you first had access to that virus only a couple months ago. That’s 
not long.

[To make a vaccine] you first need to make a decision as to what approach you 
want to take. Then you have to do extensive animal model testing to make sure 
that the approach that you’ve taken is safe in animals, and that it induces an 
immune response which would likely be protective. Then you gradually do studies 
in people to make sure it’s safe, and then to make sure that it induces an 
immune response. That takes time, a lot of time, typically years. Then and only 
then, are you ready to put it into people to see whether or not it works in an 
outbreak situation.

In 2018, after the World Health Organization declared an Ebola outbreak in the 
Democratic Republic of Congo, there was an experimental vaccine very quickly.

I think people got fooled by Ebola. When the outbreak occurred in West Africa 
and we had a vaccine pretty much that rolled off shelf within weeks, people 
thought, Ha! That’s easy.

But what they didn’t realize is people have been working on an Ebola vaccine 
for 20 years. They’ve done the animal model testing. They’ve done the testing 
to make sure that the vaccine was safe and was immunogenic.

But that’s not true here. This is a new virus. So we’re starting from scratch.

What is it about this virus that makes people confident that a vaccine will be 
available?

I don’t know. You know, I’d say about 15% to 20% of the respiratory infections 
that we see in our hospital in the winter months are [types of] coronavirus. 
This is a virus that has been around for 50 years.

But here are these three newer strains of coronavirus — MERS, SARS, and now 
this COVID-19. The first two viruses, SARS and MERS, have come and gone.

I think this [COVID-19] virus likely will come back because it’s different. If 
you were infected with SARS or MERS viruses, you were sick. And it’s very easy 
to tell who was sick and who wasn’t. You could then quarantine those people — 
put a moat around them, if you will — so that they wouldn’t infect others. So 
those infections quickly died out. This virus is more like flu. It spreads in a 
similar manner to flu by respiratory droplet. It’s about as contagious as flu. 
It has the same set of symptoms as flu. And I think in the end, frankly, it’s 
going to have the same mortality rate as flu.

There are certainly human studies showing that if you’re infected with a 
coronavirus — meaning one of the typical coronaviruses — you can have immunity 
to that strain for at least a year and probably longer. That’s encouraging. If 
natural infection can protect you, then it’s encouraging that it can produce an 
immune response which is protective and which you should be able to mimic with 
vaccination.

Vaccine development is tightly regulated. How much of that is about safety vs. 
red tape?

If you’re going to be testing this in otherwise healthy people who are very, 
very unlikely to die from this infection, you better make sure it’s safe. So 
you want those regulations in 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Andrew Strasfogel via Mercedes
But if you're an antivaxxer that is exactly what you want!

On Fri, Mar 13, 2020 at 3:42 PM Floyd Thursby via Mercedes <
mercedes@okiebenz.com> wrote:

> Yeah, so if it starts having adverse effects the media will start
> howling and Trump will be blamed for inadequate testing etcetc
> blahblahblah and the lawyers will have a field day filing billions in
> claims against the vax manufacturers
>
> --FT
>
> On 3/13/20 3:19 PM, Andrew Strasfogel via Mercedes wrote:
> > What takes 1-2 years is the testing to determine 1) is it safe on humans?
> > and 2) does it work?
> >
> > On Fri, Mar 13, 2020 at 3:15 PM Meade Dillon via Mercedes <
> > mercedes@okiebenz.com> wrote:
> >
> >> Let me try again, this link should work
> >>
> >>
> >>
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-mostread
> >>
> >> " *A Canadian company says that it has *produced a COVID-19 vaccine
> just 20
> >> days after receiving the coronavirus’s genetic sequence, using a unique
> >> technology that they soon hope to submit for FDA approval.
> >>
> >> Medicago CEO Bruce Clark said his company could produce as many as 10
> >> million doses a month. If regulatory hurdles can be cleared, he said in
> a
> >> Thursday interview, the vaccine could start to become available
> >> in November 2021. "
> >> -
> >> Max
> >> Charleston SC
> >>
> >>
> >> On Fri, Mar 13, 2020 at 3:06 PM Max Dillon 
> wrote:
> >>
> >>> Looks like some companies think they've already got a vaccine ready for
> >>> testing.
> >>>
> >>>
> >>>
> >>
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
> >>>
> >>> Max Dillon
> >>> Charleston SC
> >>>
> >>> Mar 13, 2020 12:24:51 PM archer75--- via Mercedes <
> mercedes@okiebenz.com
> >>> :
> >>>
> 
> 
>  Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> 
> 
>  At a White House news conference Tuesday, Anthony Fauci, the head of
> >> the
> >>> National Institute of Allergy and Infectious Disease, told President
> >> Donald
> >>> Trump a coronavirus vaccine would likely not be available within the
> next
> >>> year or two. Trump responded: “I like the sound of a couple of months
> >>> better.”
>  But a vaccine is not going to be available in the next couple of
> >> months,
> >>> and according to Dr. Paul Offit, that’s appropriate. Offit, director of
> >> the
> >>> Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> >>> co-developer of the rotavirus vaccine. It took roughly 26 years to
> >> perfect
> >>> that protection against a disease that, according to the Centers for
> >>> Disease Control and Prevention, was the leading cause for severe
> diarrhea
> >>> in children before the vaccine’s introduction in 2006.
>  Why is it unrealistic to expect a vaccine for coronavirus in a few
> >>> months?
>  Nobody’s ever seen this virus before. Therefore, if you’re interested
> >> in
> >>> making a vaccine, you first had access to that virus only a couple
> months
> >>> ago. That’s not long.
>  [To make a vaccine] you first need to make a decision as to what
> >>> approach you want to take. Then you have to do extensive animal model
> >>> testing to make sure that the approach that you’ve taken is safe in
> >>> animals, and that it induces an immune response which would likely be
> >>> protective. Then you gradually do studies in people to make sure it’s
> >> safe,
> >>> and then to make sure that it induces an immune response. That takes
> >> time,
> >>> a lot of time, typically years. Then and only then, are you ready to
> put
> >> it
> >>> into people to see whether or not it works in an outbreak situation.
>  In 2018, after the World Health Organization declared an Ebola
> outbreak
> >>> in the Democratic Republic of Congo, there was an experimental vaccine
> >> very
> >>> quickly.
>  I think people got fooled by Ebola. When the outbreak occurred in West
> >>> Africa and we had a vaccine pretty much that rolled off shelf within
> >> weeks,
> >>> people thought, Ha! That’s easy.
>  But what they didn’t realize is people have been working on an Ebola
> >>> vaccine for 20 years. They’ve done the animal model testing. They’ve
> done
> >>> the testing to make sure that the vaccine was safe and was immunogenic.
>  But that’s not true here. This is a new virus. So we’re starting from
> >>> scratch.
>  What is it about this virus that makes people confident that a vaccine
> >>> will be available?
>  I don’t know. You know, I’d say about 15% to 20% of the respiratory
> >>> infections that we see in our hospital in the winter months are [types
> >> of]
> >>> coronavirus. This is a virus that has been around for 50 years.
>  But here are these three newer strains of coronavirus — MERS, SARS,
> and
> >>> now this COVID-19. The first two viruses, SARS and MERS, have come and
> >> gone.
>  I think this [COVID-19] 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Floyd Thursby via Mercedes
Yeah, so if it starts having adverse effects the media will start 
howling and Trump will be blamed for inadequate testing etcetc 
blahblahblah and the lawyers will have a field day filing billions in 
claims against the vax manufacturers


--FT

On 3/13/20 3:19 PM, Andrew Strasfogel via Mercedes wrote:

What takes 1-2 years is the testing to determine 1) is it safe on humans?
and 2) does it work?

On Fri, Mar 13, 2020 at 3:15 PM Meade Dillon via Mercedes <
mercedes@okiebenz.com> wrote:


Let me try again, this link should work


https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-mostread

" *A Canadian company says that it has *produced a COVID-19 vaccine just 20
days after receiving the coronavirus’s genetic sequence, using a unique
technology that they soon hope to submit for FDA approval.

Medicago CEO Bruce Clark said his company could produce as many as 10
million doses a month. If regulatory hurdles can be cleared, he said in a
Thursday interview, the vaccine could start to become available
in November 2021. "
-
Max
Charleston SC


On Fri, Mar 13, 2020 at 3:06 PM Max Dillon  wrote:


Looks like some companies think they've already got a vaccine ready for
testing.




https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/


Max Dillon
Charleston SC

Mar 13, 2020 12:24:51 PM archer75--- via Mercedes 


Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q


At a White House news conference Tuesday, Anthony Fauci, the head of

the

National Institute of Allergy and Infectious Disease, told President

Donald

Trump a coronavirus vaccine would likely not be available within the next
year or two. Trump responded: “I like the sound of a couple of months
better.”

But a vaccine is not going to be available in the next couple of

months,

and according to Dr. Paul Offit, that’s appropriate. Offit, director of

the

Vaccine Education Center at Children’s Hospital of Philadelphia, is the
co-developer of the rotavirus vaccine. It took roughly 26 years to

perfect

that protection against a disease that, according to the Centers for
Disease Control and Prevention, was the leading cause for severe diarrhea
in children before the vaccine’s introduction in 2006.

Why is it unrealistic to expect a vaccine for coronavirus in a few

months?

Nobody’s ever seen this virus before. Therefore, if you’re interested

in

making a vaccine, you first had access to that virus only a couple months
ago. That’s not long.

[To make a vaccine] you first need to make a decision as to what

approach you want to take. Then you have to do extensive animal model
testing to make sure that the approach that you’ve taken is safe in
animals, and that it induces an immune response which would likely be
protective. Then you gradually do studies in people to make sure it’s

safe,

and then to make sure that it induces an immune response. That takes

time,

a lot of time, typically years. Then and only then, are you ready to put

it

into people to see whether or not it works in an outbreak situation.

In 2018, after the World Health Organization declared an Ebola outbreak

in the Democratic Republic of Congo, there was an experimental vaccine

very

quickly.

I think people got fooled by Ebola. When the outbreak occurred in West

Africa and we had a vaccine pretty much that rolled off shelf within

weeks,

people thought, Ha! That’s easy.

But what they didn’t realize is people have been working on an Ebola

vaccine for 20 years. They’ve done the animal model testing. They’ve done
the testing to make sure that the vaccine was safe and was immunogenic.

But that’s not true here. This is a new virus. So we’re starting from

scratch.

What is it about this virus that makes people confident that a vaccine

will be available?

I don’t know. You know, I’d say about 15% to 20% of the respiratory

infections that we see in our hospital in the winter months are [types

of]

coronavirus. This is a virus that has been around for 50 years.

But here are these three newer strains of coronavirus — MERS, SARS, and

now this COVID-19. The first two viruses, SARS and MERS, have come and

gone.

I think this [COVID-19] virus likely will come back because it’s

different. If you were infected with SARS or MERS viruses, you were sick.
And it’s very easy to tell who was sick and who wasn’t. You could then
quarantine those people — put a moat around them, if you will — so that
they wouldn’t infect others. So those infections quickly died out. This
virus is more like flu. It spreads in a similar manner to flu by
respiratory droplet. It’s about as contagious as flu. It has the same set
of symptoms as flu. And I think in the end, frankly, it’s going to have

the

same mortality rate as flu.

There are certainly human studies showing that if you’re infected with

a

coronavirus — meaning one of the typical coronaviruses — you can have

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Andrew Strasfogel via Mercedes
What takes 1-2 years is the testing to determine 1) is it safe on humans?
and 2) does it work?

On Fri, Mar 13, 2020 at 3:15 PM Meade Dillon via Mercedes <
mercedes@okiebenz.com> wrote:

> Let me try again, this link should work
>
>
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-mostread
>
> " *A Canadian company says that it has *produced a COVID-19 vaccine just 20
> days after receiving the coronavirus’s genetic sequence, using a unique
> technology that they soon hope to submit for FDA approval.
>
> Medicago CEO Bruce Clark said his company could produce as many as 10
> million doses a month. If regulatory hurdles can be cleared, he said in a
> Thursday interview, the vaccine could start to become available
> in November 2021. "
> -
> Max
> Charleston SC
>
>
> On Fri, Mar 13, 2020 at 3:06 PM Max Dillon  wrote:
>
> > Looks like some companies think they've already got a vaccine ready for
> > testing.
> >
> >
> >
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
> >
> >
> > Max Dillon
> > Charleston SC
> >
> > Mar 13, 2020 12:24:51 PM archer75--- via Mercedes  >:
> >
> > >
> > >
> > >
> > > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> > >
> > >
> > > At a White House news conference Tuesday, Anthony Fauci, the head of
> the
> > National Institute of Allergy and Infectious Disease, told President
> Donald
> > Trump a coronavirus vaccine would likely not be available within the next
> > year or two. Trump responded: “I like the sound of a couple of months
> > better.”
> > >
> > > But a vaccine is not going to be available in the next couple of
> months,
> > and according to Dr. Paul Offit, that’s appropriate. Offit, director of
> the
> > Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> > co-developer of the rotavirus vaccine. It took roughly 26 years to
> perfect
> > that protection against a disease that, according to the Centers for
> > Disease Control and Prevention, was the leading cause for severe diarrhea
> > in children before the vaccine’s introduction in 2006.
> > >
> > > Why is it unrealistic to expect a vaccine for coronavirus in a few
> > months?
> > >
> > > Nobody’s ever seen this virus before. Therefore, if you’re interested
> in
> > making a vaccine, you first had access to that virus only a couple months
> > ago. That’s not long.
> > >
> > > [To make a vaccine] you first need to make a decision as to what
> > approach you want to take. Then you have to do extensive animal model
> > testing to make sure that the approach that you’ve taken is safe in
> > animals, and that it induces an immune response which would likely be
> > protective. Then you gradually do studies in people to make sure it’s
> safe,
> > and then to make sure that it induces an immune response. That takes
> time,
> > a lot of time, typically years. Then and only then, are you ready to put
> it
> > into people to see whether or not it works in an outbreak situation.
> > >
> > > In 2018, after the World Health Organization declared an Ebola outbreak
> > in the Democratic Republic of Congo, there was an experimental vaccine
> very
> > quickly.
> > >
> > > I think people got fooled by Ebola. When the outbreak occurred in West
> > Africa and we had a vaccine pretty much that rolled off shelf within
> weeks,
> > people thought, Ha! That’s easy.
> > >
> > > But what they didn’t realize is people have been working on an Ebola
> > vaccine for 20 years. They’ve done the animal model testing. They’ve done
> > the testing to make sure that the vaccine was safe and was immunogenic.
> > >
> > > But that’s not true here. This is a new virus. So we’re starting from
> > scratch.
> > >
> > > What is it about this virus that makes people confident that a vaccine
> > will be available?
> > >
> > > I don’t know. You know, I’d say about 15% to 20% of the respiratory
> > infections that we see in our hospital in the winter months are [types
> of]
> > coronavirus. This is a virus that has been around for 50 years.
> > >
> > > But here are these three newer strains of coronavirus — MERS, SARS, and
> > now this COVID-19. The first two viruses, SARS and MERS, have come and
> gone.
> > >
> > > I think this [COVID-19] virus likely will come back because it’s
> > different. If you were infected with SARS or MERS viruses, you were sick.
> > And it’s very easy to tell who was sick and who wasn’t. You could then
> > quarantine those people — put a moat around them, if you will — so that
> > they wouldn’t infect others. So those infections quickly died out. This
> > virus is more like flu. It spreads in a similar manner to flu by
> > respiratory droplet. It’s about as contagious as flu. It has the same set
> > of symptoms as flu. And I think in the end, frankly, it’s going to have
> the
> > same mortality rate as flu.
> > >
> > > There are certainly human studies showing that 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Meade Dillon via Mercedes
Let me try again, this link should work

https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/163739/?oref=d-mostread

" *A Canadian company says that it has *produced a COVID-19 vaccine just 20
days after receiving the coronavirus’s genetic sequence, using a unique
technology that they soon hope to submit for FDA approval.

Medicago CEO Bruce Clark said his company could produce as many as 10
million doses a month. If regulatory hurdles can be cleared, he said in a
Thursday interview, the vaccine could start to become available
in November 2021. "
-
Max
Charleston SC


On Fri, Mar 13, 2020 at 3:06 PM Max Dillon  wrote:

> Looks like some companies think they've already got a vaccine ready for
> testing.
>
>
> https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/
>
>
> Max Dillon
> Charleston SC
>
> Mar 13, 2020 12:24:51 PM archer75--- via Mercedes :
>
> >
> >
> >
> > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> >
> >
> > At a White House news conference Tuesday, Anthony Fauci, the head of the
> National Institute of Allergy and Infectious Disease, told President Donald
> Trump a coronavirus vaccine would likely not be available within the next
> year or two. Trump responded: “I like the sound of a couple of months
> better.”
> >
> > But a vaccine is not going to be available in the next couple of months,
> and according to Dr. Paul Offit, that’s appropriate. Offit, director of the
> Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> co-developer of the rotavirus vaccine. It took roughly 26 years to perfect
> that protection against a disease that, according to the Centers for
> Disease Control and Prevention, was the leading cause for severe diarrhea
> in children before the vaccine’s introduction in 2006.
> >
> > Why is it unrealistic to expect a vaccine for coronavirus in a few
> months?
> >
> > Nobody’s ever seen this virus before. Therefore, if you’re interested in
> making a vaccine, you first had access to that virus only a couple months
> ago. That’s not long.
> >
> > [To make a vaccine] you first need to make a decision as to what
> approach you want to take. Then you have to do extensive animal model
> testing to make sure that the approach that you’ve taken is safe in
> animals, and that it induces an immune response which would likely be
> protective. Then you gradually do studies in people to make sure it’s safe,
> and then to make sure that it induces an immune response. That takes time,
> a lot of time, typically years. Then and only then, are you ready to put it
> into people to see whether or not it works in an outbreak situation.
> >
> > In 2018, after the World Health Organization declared an Ebola outbreak
> in the Democratic Republic of Congo, there was an experimental vaccine very
> quickly.
> >
> > I think people got fooled by Ebola. When the outbreak occurred in West
> Africa and we had a vaccine pretty much that rolled off shelf within weeks,
> people thought, Ha! That’s easy.
> >
> > But what they didn’t realize is people have been working on an Ebola
> vaccine for 20 years. They’ve done the animal model testing. They’ve done
> the testing to make sure that the vaccine was safe and was immunogenic.
> >
> > But that’s not true here. This is a new virus. So we’re starting from
> scratch.
> >
> > What is it about this virus that makes people confident that a vaccine
> will be available?
> >
> > I don’t know. You know, I’d say about 15% to 20% of the respiratory
> infections that we see in our hospital in the winter months are [types of]
> coronavirus. This is a virus that has been around for 50 years.
> >
> > But here are these three newer strains of coronavirus — MERS, SARS, and
> now this COVID-19. The first two viruses, SARS and MERS, have come and gone.
> >
> > I think this [COVID-19] virus likely will come back because it’s
> different. If you were infected with SARS or MERS viruses, you were sick.
> And it’s very easy to tell who was sick and who wasn’t. You could then
> quarantine those people — put a moat around them, if you will — so that
> they wouldn’t infect others. So those infections quickly died out. This
> virus is more like flu. It spreads in a similar manner to flu by
> respiratory droplet. It’s about as contagious as flu. It has the same set
> of symptoms as flu. And I think in the end, frankly, it’s going to have the
> same mortality rate as flu.
> >
> > There are certainly human studies showing that if you’re infected with a
> coronavirus — meaning one of the typical coronaviruses — you can have
> immunity to that strain for at least a year and probably longer. That’s
> encouraging. If natural infection can protect you, then it’s encouraging
> that it can produce an immune response which is protective and which you
> should be able to mimic with vaccination.
> >
> > Vaccine development is tightly regulated. How 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Floyd Thursby via Mercedes

And vaccines would give me autism

--FT

On 3/13/20 2:58 PM, Andrew Strasfogel wrote:

I flushed at least one out into the open.  Any others?

On Fri, Mar 13, 2020 at 2:56 PM Floyd Thursby via Mercedes 
mailto:mercedes@okiebenz.com>> wrote:


It's a way to poison our precious bodily fluids just like the commie
fluoridation of our water supplies!

--FT

On 3/13/20 2:06 PM, Andrew Strasfogel via Mercedes wrote:
> Who on the list is an antivaxxer?
>
> On Fri, Mar 13, 2020 at 12:29 PM Meade Dillon via Mercedes <
> mercedes@okiebenz.com > wrote:
>
>> Thanks Gerry, some common sense there.
>>
>> " There’s a virus that the CDC currently estimated has killed
between
>> 20,000 and 45,000 people in the United States -- influenza. But
only half
>> the country gets that vaccine.
>>
>> There’s only 14 deaths [in the U.S., as of Friday afternoon]
from COVID-19,
>> but everybody would get a vaccine now.
>>
>> The point being: We’re not very good at assessing risk."
>>
>> I think we are up to 40 dead now from this Wuhan flu.
>> -
>> Max
>> Charleston SC
>>
>>
>> On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
>> mercedes@okiebenz.com > wrote:
>>
>>>
>>>
>>> Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
>>>
>>>
>>> At a White House news conference Tuesday, Anthony Fauci, the
head of the
>>> National Institute of Allergy and Infectious Disease, told
President
>> Donald
>>> Trump a coronavirus vaccine would likely not be available
within the next
>>> year or two. Trump responded: “I like the sound of a couple of
months
>>> better.”
>>>
>>> But a vaccine is not going to be available in the next couple
of months,
>>> and according to Dr. Paul Offit, that’s appropriate. Offit,
director of
>> the
>>> Vaccine Education Center at Children’s Hospital of
Philadelphia, is the
>>> co-developer of the rotavirus vaccine. It took roughly 26 years to
>> perfect
>>> that protection against a disease that, according to the
Centers for
>>> Disease Control and Prevention, was the leading cause for
severe diarrhea
>>> in children before the vaccine’s introduction in 2006.
>>>
>>> Why is it unrealistic to expect a vaccine for coronavirus in a few
>> months?
>>> Nobody’s ever seen this virus before. Therefore, if you’re
interested in
>>> making a vaccine, you first had access to that virus only a
couple months
>>> ago. That’s not long.
>>>
>>> [To make a vaccine] you first need to make a decision as to
what approach
>>> you want to take. Then you have to do extensive animal model
testing to
>>> make sure that the approach that you’ve taken is safe in
animals, and
>> that
>>> it induces an immune response which would likely be
protective. Then you
>>> gradually do studies in people to make sure it’s safe, and
then to make
>>> sure that it induces an immune response. That takes time, a
lot of time,
>>> typically years. Then and only then, are you ready to put it
into people
>> to
>>> see whether or not it works in an outbreak situation.
>>>
>>> In 2018, after the World Health Organization declared an Ebola
outbreak
>> in
>>> the Democratic Republic of Congo, there was an experimental
vaccine very
>>> quickly.
>>>
>>> I think people got fooled by Ebola. When the outbreak occurred
in West
>>> Africa and we had a vaccine pretty much that rolled off shelf
within
>> weeks,
>>> people thought, Ha! That’s easy.
>>>
>>> But what they didn’t realize is people have been working on an
Ebola
>>> vaccine for 20 years. They’ve done the animal model testing.
They’ve done
>>> the testing to make sure that the vaccine was safe and was
immunogenic.
>>>
>>> But that’s not true here. This is a new virus. So we’re
starting from
>>> scratch.
>>>
>>> What is it about this virus that makes people confident that a
vaccine
>>> will be available?
>>>
>>> I don’t know. You know, I’d say about 15% to 20% of the
respiratory
>>> infections that we see in our hospital in the winter months
are [types
>> of]
>>> coronavirus. This is a virus that has been around for 50 years.
>>>
>>> But here are these three newer strains of coronavirus — MERS,
SARS, and
>>> now this COVID-19. The first two viruses, SARS and MERS, have
come and
>> gone.
>>> I think this [COVID-19] virus likely will come back because it’s
>>> different. If you were infected with SARS or MERS viruses, you
were sick.
>>> And it’s very easy to tell who was sick and who wasn’t. You
could 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread dan--- via Mercedes
I’ve heard that women seek your essence. Feeling a profound sense of loss?

Group Captain Lionel Mandrake

> On Mar 13, 2020, at 2:55 PM, Floyd Thursby via Mercedes 
>  wrote:
> 
> It's a way to poison our precious bodily fluids just like the commie 
> fluoridation of our water supplies!
> 
> --FT
> 
>> On 3/13/20 2:06 PM, Andrew Strasfogel via Mercedes wrote:
>> Who on the list is an antivaxxer?
>> 
>> On Fri, Mar 13, 2020 at 12:29 PM Meade Dillon via Mercedes <
>> mercedes@okiebenz.com> wrote:
>> 
>>> Thanks Gerry, some common sense there.
>>> 
>>> " There’s a virus that the CDC currently estimated has killed between
>>> 20,000 and 45,000 people in the United States -- influenza. But only half
>>> the country gets that vaccine.
>>> 
>>> There’s only 14 deaths [in the U.S., as of Friday afternoon] from COVID-19,
>>> but everybody would get a vaccine now.
>>> 
>>> The point being: We’re not very good at assessing risk."
>>> 
>>> I think we are up to 40 dead now from this Wuhan flu.
>>> -
>>> Max
>>> Charleston SC
>>> 
>>> 
>>> On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
>>> mercedes@okiebenz.com> wrote:
>>> 
 
 
 Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
 
 
 At a White House news conference Tuesday, Anthony Fauci, the head of the
 National Institute of Allergy and Infectious Disease, told President
>>> Donald
 Trump a coronavirus vaccine would likely not be available within the next
 year or two. Trump responded: “I like the sound of a couple of months
 better.”
 
 But a vaccine is not going to be available in the next couple of months,
 and according to Dr. Paul Offit, that’s appropriate. Offit, director of
>>> the
 Vaccine Education Center at Children’s Hospital of Philadelphia, is the
 co-developer of the rotavirus vaccine. It took roughly 26 years to
>>> perfect
 that protection against a disease that, according to the Centers for
 Disease Control and Prevention, was the leading cause for severe diarrhea
 in children before the vaccine’s introduction in 2006.
 
 Why is it unrealistic to expect a vaccine for coronavirus in a few
>>> months?
 Nobody’s ever seen this virus before. Therefore, if you’re interested in
 making a vaccine, you first had access to that virus only a couple months
 ago. That’s not long.
 
 [To make a vaccine] you first need to make a decision as to what approach
 you want to take. Then you have to do extensive animal model testing to
 make sure that the approach that you’ve taken is safe in animals, and
>>> that
 it induces an immune response which would likely be protective. Then you
 gradually do studies in people to make sure it’s safe, and then to make
 sure that it induces an immune response. That takes time, a lot of time,
 typically years. Then and only then, are you ready to put it into people
>>> to
 see whether or not it works in an outbreak situation.
 
 In 2018, after the World Health Organization declared an Ebola outbreak
>>> in
 the Democratic Republic of Congo, there was an experimental vaccine very
 quickly.
 
 I think people got fooled by Ebola. When the outbreak occurred in West
 Africa and we had a vaccine pretty much that rolled off shelf within
>>> weeks,
 people thought, Ha! That’s easy.
 
 But what they didn’t realize is people have been working on an Ebola
 vaccine for 20 years. They’ve done the animal model testing. They’ve done
 the testing to make sure that the vaccine was safe and was immunogenic.
 
 But that’s not true here. This is a new virus. So we’re starting from
 scratch.
 
 What is it about this virus that makes people confident that a vaccine
 will be available?
 
 I don’t know. You know, I’d say about 15% to 20% of the respiratory
 infections that we see in our hospital in the winter months are [types
>>> of]
 coronavirus. This is a virus that has been around for 50 years.
 
 But here are these three newer strains of coronavirus — MERS, SARS, and
 now this COVID-19. The first two viruses, SARS and MERS, have come and
>>> gone.
 I think this [COVID-19] virus likely will come back because it’s
 different. If you were infected with SARS or MERS viruses, you were sick.
 And it’s very easy to tell who was sick and who wasn’t. You could then
 quarantine those people — put a moat around them, if you will — so that
 they wouldn’t infect others. So those infections quickly died out. This
 virus is more like flu. It spreads in a similar manner to flu by
 respiratory droplet. It’s about as contagious as flu. It has the same set
 of symptoms as flu. And I think in the end, frankly, it’s going to have
>>> the
 same mortality rate as flu.
 
 There are certainly human studies showing that if you’re infected with a
 coronavirus — 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Max Dillon via Mercedes
Looks like some companies think they've already got a vaccine ready for testing.

https://www.defenseone.com/technology/2020/03/breaking-weve-got-vaccine-says-pentagon-funded-company/


Max Dillon
Charleston SC

Mar 13, 2020 12:24:51 PM archer75--- via Mercedes :

> 
> 
> 
> Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> 
> 
> At a White House news conference Tuesday, Anthony Fauci, the head of the 
> National Institute of Allergy and Infectious Disease, told President Donald 
> Trump a coronavirus vaccine would likely not be available within the next 
> year or two. Trump responded: “I like the sound of a couple of months better.”
> 
> But a vaccine is not going to be available in the next couple of months, and 
> according to Dr. Paul Offit, that’s appropriate. Offit, director of the 
> Vaccine Education Center at Children’s Hospital of Philadelphia, is the 
> co-developer of the rotavirus vaccine. It took roughly 26 years to perfect 
> that protection against a disease that, according to the Centers for Disease 
> Control and Prevention, was the leading cause for severe diarrhea in children 
> before the vaccine’s introduction in 2006.
> 
> Why is it unrealistic to expect a vaccine for coronavirus in a few months?
> 
> Nobody’s ever seen this virus before. Therefore, if you’re interested in 
> making a vaccine, you first had access to that virus only a couple months 
> ago. That’s not long.
> 
> [To make a vaccine] you first need to make a decision as to what approach you 
> want to take. Then you have to do extensive animal model testing to make sure 
> that the approach that you’ve taken is safe in animals, and that it induces 
> an immune response which would likely be protective. Then you gradually do 
> studies in people to make sure it’s safe, and then to make sure that it 
> induces an immune response. That takes time, a lot of time, typically years. 
> Then and only then, are you ready to put it into people to see whether or not 
> it works in an outbreak situation.
> 
> In 2018, after the World Health Organization declared an Ebola outbreak in 
> the Democratic Republic of Congo, there was an experimental vaccine very 
> quickly.
> 
> I think people got fooled by Ebola. When the outbreak occurred in West Africa 
> and we had a vaccine pretty much that rolled off shelf within weeks, people 
> thought, Ha! That’s easy.
> 
> But what they didn’t realize is people have been working on an Ebola vaccine 
> for 20 years. They’ve done the animal model testing. They’ve done the testing 
> to make sure that the vaccine was safe and was immunogenic.
> 
> But that’s not true here. This is a new virus. So we’re starting from scratch.
> 
> What is it about this virus that makes people confident that a vaccine will 
> be available?
> 
> I don’t know. You know, I’d say about 15% to 20% of the respiratory 
> infections that we see in our hospital in the winter months are [types of] 
> coronavirus. This is a virus that has been around for 50 years.
> 
> But here are these three newer strains of coronavirus — MERS, SARS, and now 
> this COVID-19. The first two viruses, SARS and MERS, have come and gone.
> 
> I think this [COVID-19] virus likely will come back because it’s different. 
> If you were infected with SARS or MERS viruses, you were sick. And it’s very 
> easy to tell who was sick and who wasn’t. You could then quarantine those 
> people — put a moat around them, if you will — so that they wouldn’t infect 
> others. So those infections quickly died out. This virus is more like flu. It 
> spreads in a similar manner to flu by respiratory droplet. It’s about as 
> contagious as flu. It has the same set of symptoms as flu. And I think in the 
> end, frankly, it’s going to have the same mortality rate as flu.
> 
> There are certainly human studies showing that if you’re infected with a 
> coronavirus — meaning one of the typical coronaviruses — you can have 
> immunity to that strain for at least a year and probably longer. That’s 
> encouraging. If natural infection can protect you, then it’s encouraging that 
> it can produce an immune response which is protective and which you should be 
> able to mimic with vaccination.
> 
> Vaccine development is tightly regulated. How much of that is about safety 
> vs. red tape?
> 
> If you’re going to be testing this in otherwise healthy people who are very, 
> very unlikely to die from this infection, you better make sure it’s safe. So 
> you want those regulations in place.
> 
> An example is the dengue vaccine. When it was tested in Latin America and 
> Philippines, it was found to actually increase your risk of dengue shock 
> syndrome. Children who were less than 9 years of age, who had never been 
> exposed to the virus before, were actually more likely to be hurt by the 
> vaccine than helped by it. Now, you only knew that from doing large clinical 
> trials with tens of thousands of people.
> 
> The history of medical breakthroughs is 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Andrew Strasfogel via Mercedes
I flushed at least one out into the open.  Any others?

On Fri, Mar 13, 2020 at 2:56 PM Floyd Thursby via Mercedes <
mercedes@okiebenz.com> wrote:

> It's a way to poison our precious bodily fluids just like the commie
> fluoridation of our water supplies!
>
> --FT
>
> On 3/13/20 2:06 PM, Andrew Strasfogel via Mercedes wrote:
> > Who on the list is an antivaxxer?
> >
> > On Fri, Mar 13, 2020 at 12:29 PM Meade Dillon via Mercedes <
> > mercedes@okiebenz.com> wrote:
> >
> >> Thanks Gerry, some common sense there.
> >>
> >> " There’s a virus that the CDC currently estimated has killed between
> >> 20,000 and 45,000 people in the United States -- influenza. But only
> half
> >> the country gets that vaccine.
> >>
> >> There’s only 14 deaths [in the U.S., as of Friday afternoon] from
> COVID-19,
> >> but everybody would get a vaccine now.
> >>
> >> The point being: We’re not very good at assessing risk."
> >>
> >> I think we are up to 40 dead now from this Wuhan flu.
> >> -
> >> Max
> >> Charleston SC
> >>
> >>
> >> On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
> >> mercedes@okiebenz.com> wrote:
> >>
> >>>
> >>>
> >>> Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> >>>
> >>>
> >>> At a White House news conference Tuesday, Anthony Fauci, the head of
> the
> >>> National Institute of Allergy and Infectious Disease, told President
> >> Donald
> >>> Trump a coronavirus vaccine would likely not be available within the
> next
> >>> year or two. Trump responded: “I like the sound of a couple of months
> >>> better.”
> >>>
> >>> But a vaccine is not going to be available in the next couple of
> months,
> >>> and according to Dr. Paul Offit, that’s appropriate. Offit, director of
> >> the
> >>> Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> >>> co-developer of the rotavirus vaccine. It took roughly 26 years to
> >> perfect
> >>> that protection against a disease that, according to the Centers for
> >>> Disease Control and Prevention, was the leading cause for severe
> diarrhea
> >>> in children before the vaccine’s introduction in 2006.
> >>>
> >>> Why is it unrealistic to expect a vaccine for coronavirus in a few
> >> months?
> >>> Nobody’s ever seen this virus before. Therefore, if you’re interested
> in
> >>> making a vaccine, you first had access to that virus only a couple
> months
> >>> ago. That’s not long.
> >>>
> >>> [To make a vaccine] you first need to make a decision as to what
> approach
> >>> you want to take. Then you have to do extensive animal model testing to
> >>> make sure that the approach that you’ve taken is safe in animals, and
> >> that
> >>> it induces an immune response which would likely be protective. Then
> you
> >>> gradually do studies in people to make sure it’s safe, and then to make
> >>> sure that it induces an immune response. That takes time, a lot of
> time,
> >>> typically years. Then and only then, are you ready to put it into
> people
> >> to
> >>> see whether or not it works in an outbreak situation.
> >>>
> >>> In 2018, after the World Health Organization declared an Ebola outbreak
> >> in
> >>> the Democratic Republic of Congo, there was an experimental vaccine
> very
> >>> quickly.
> >>>
> >>> I think people got fooled by Ebola. When the outbreak occurred in West
> >>> Africa and we had a vaccine pretty much that rolled off shelf within
> >> weeks,
> >>> people thought, Ha! That’s easy.
> >>>
> >>> But what they didn’t realize is people have been working on an Ebola
> >>> vaccine for 20 years. They’ve done the animal model testing. They’ve
> done
> >>> the testing to make sure that the vaccine was safe and was immunogenic.
> >>>
> >>> But that’s not true here. This is a new virus. So we’re starting from
> >>> scratch.
> >>>
> >>> What is it about this virus that makes people confident that a vaccine
> >>> will be available?
> >>>
> >>> I don’t know. You know, I’d say about 15% to 20% of the respiratory
> >>> infections that we see in our hospital in the winter months are [types
> >> of]
> >>> coronavirus. This is a virus that has been around for 50 years.
> >>>
> >>> But here are these three newer strains of coronavirus — MERS, SARS, and
> >>> now this COVID-19. The first two viruses, SARS and MERS, have come and
> >> gone.
> >>> I think this [COVID-19] virus likely will come back because it’s
> >>> different. If you were infected with SARS or MERS viruses, you were
> sick.
> >>> And it’s very easy to tell who was sick and who wasn’t. You could then
> >>> quarantine those people — put a moat around them, if you will — so that
> >>> they wouldn’t infect others. So those infections quickly died out. This
> >>> virus is more like flu. It spreads in a similar manner to flu by
> >>> respiratory droplet. It’s about as contagious as flu. It has the same
> set
> >>> of symptoms as flu. And I think in the end, frankly, it’s going to have
> >> the
> >>> same mortality rate as flu.
> >>>
> >>> There are certainly 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Floyd Thursby via Mercedes
It's a way to poison our precious bodily fluids just like the commie 
fluoridation of our water supplies!


--FT

On 3/13/20 2:06 PM, Andrew Strasfogel via Mercedes wrote:

Who on the list is an antivaxxer?

On Fri, Mar 13, 2020 at 12:29 PM Meade Dillon via Mercedes <
mercedes@okiebenz.com> wrote:


Thanks Gerry, some common sense there.

" There’s a virus that the CDC currently estimated has killed between
20,000 and 45,000 people in the United States -- influenza. But only half
the country gets that vaccine.

There’s only 14 deaths [in the U.S., as of Friday afternoon] from COVID-19,
but everybody would get a vaccine now.

The point being: We’re not very good at assessing risk."

I think we are up to 40 dead now from this Wuhan flu.
-
Max
Charleston SC


On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
mercedes@okiebenz.com> wrote:




Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q


At a White House news conference Tuesday, Anthony Fauci, the head of the
National Institute of Allergy and Infectious Disease, told President

Donald

Trump a coronavirus vaccine would likely not be available within the next
year or two. Trump responded: “I like the sound of a couple of months
better.”

But a vaccine is not going to be available in the next couple of months,
and according to Dr. Paul Offit, that’s appropriate. Offit, director of

the

Vaccine Education Center at Children’s Hospital of Philadelphia, is the
co-developer of the rotavirus vaccine. It took roughly 26 years to

perfect

that protection against a disease that, according to the Centers for
Disease Control and Prevention, was the leading cause for severe diarrhea
in children before the vaccine’s introduction in 2006.

Why is it unrealistic to expect a vaccine for coronavirus in a few

months?

Nobody’s ever seen this virus before. Therefore, if you’re interested in
making a vaccine, you first had access to that virus only a couple months
ago. That’s not long.

[To make a vaccine] you first need to make a decision as to what approach
you want to take. Then you have to do extensive animal model testing to
make sure that the approach that you’ve taken is safe in animals, and

that

it induces an immune response which would likely be protective. Then you
gradually do studies in people to make sure it’s safe, and then to make
sure that it induces an immune response. That takes time, a lot of time,
typically years. Then and only then, are you ready to put it into people

to

see whether or not it works in an outbreak situation.

In 2018, after the World Health Organization declared an Ebola outbreak

in

the Democratic Republic of Congo, there was an experimental vaccine very
quickly.

I think people got fooled by Ebola. When the outbreak occurred in West
Africa and we had a vaccine pretty much that rolled off shelf within

weeks,

people thought, Ha! That’s easy.

But what they didn’t realize is people have been working on an Ebola
vaccine for 20 years. They’ve done the animal model testing. They’ve done
the testing to make sure that the vaccine was safe and was immunogenic.

But that’s not true here. This is a new virus. So we’re starting from
scratch.

What is it about this virus that makes people confident that a vaccine
will be available?

I don’t know. You know, I’d say about 15% to 20% of the respiratory
infections that we see in our hospital in the winter months are [types

of]

coronavirus. This is a virus that has been around for 50 years.

But here are these three newer strains of coronavirus — MERS, SARS, and
now this COVID-19. The first two viruses, SARS and MERS, have come and

gone.

I think this [COVID-19] virus likely will come back because it’s
different. If you were infected with SARS or MERS viruses, you were sick.
And it’s very easy to tell who was sick and who wasn’t. You could then
quarantine those people — put a moat around them, if you will — so that
they wouldn’t infect others. So those infections quickly died out. This
virus is more like flu. It spreads in a similar manner to flu by
respiratory droplet. It’s about as contagious as flu. It has the same set
of symptoms as flu. And I think in the end, frankly, it’s going to have

the

same mortality rate as flu.

There are certainly human studies showing that if you’re infected with a
coronavirus — meaning one of the typical coronaviruses — you can have
immunity to that strain for at least a year and probably longer. That’s
encouraging. If natural infection can protect you, then it’s encouraging
that it can produce an immune response which is protective and which you
should be able to mimic with vaccination.

Vaccine development is tightly regulated. How much of that is about

safety

vs. red tape?

If you’re going to be testing this in otherwise healthy people who are
very, very unlikely to die from this infection, you better make sure it’s
safe. So you want those regulations in place.

An example is the dengue vaccine. When it was tested in 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Andrew Strasfogel via Mercedes
Who on the list is an antivaxxer?

On Fri, Mar 13, 2020 at 12:29 PM Meade Dillon via Mercedes <
mercedes@okiebenz.com> wrote:

> Thanks Gerry, some common sense there.
>
> " There’s a virus that the CDC currently estimated has killed between
> 20,000 and 45,000 people in the United States -- influenza. But only half
> the country gets that vaccine.
>
> There’s only 14 deaths [in the U.S., as of Friday afternoon] from COVID-19,
> but everybody would get a vaccine now.
>
> The point being: We’re not very good at assessing risk."
>
> I think we are up to 40 dead now from this Wuhan flu.
> -
> Max
> Charleston SC
>
>
> On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
> mercedes@okiebenz.com> wrote:
>
> >
> >
> >
> > Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
> >
> >
> > At a White House news conference Tuesday, Anthony Fauci, the head of the
> > National Institute of Allergy and Infectious Disease, told President
> Donald
> > Trump a coronavirus vaccine would likely not be available within the next
> > year or two. Trump responded: “I like the sound of a couple of months
> > better.”
> >
> > But a vaccine is not going to be available in the next couple of months,
> > and according to Dr. Paul Offit, that’s appropriate. Offit, director of
> the
> > Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> > co-developer of the rotavirus vaccine. It took roughly 26 years to
> perfect
> > that protection against a disease that, according to the Centers for
> > Disease Control and Prevention, was the leading cause for severe diarrhea
> > in children before the vaccine’s introduction in 2006.
> >
> > Why is it unrealistic to expect a vaccine for coronavirus in a few
> months?
> >
> > Nobody’s ever seen this virus before. Therefore, if you’re interested in
> > making a vaccine, you first had access to that virus only a couple months
> > ago. That’s not long.
> >
> > [To make a vaccine] you first need to make a decision as to what approach
> > you want to take. Then you have to do extensive animal model testing to
> > make sure that the approach that you’ve taken is safe in animals, and
> that
> > it induces an immune response which would likely be protective. Then you
> > gradually do studies in people to make sure it’s safe, and then to make
> > sure that it induces an immune response. That takes time, a lot of time,
> > typically years. Then and only then, are you ready to put it into people
> to
> > see whether or not it works in an outbreak situation.
> >
> > In 2018, after the World Health Organization declared an Ebola outbreak
> in
> > the Democratic Republic of Congo, there was an experimental vaccine very
> > quickly.
> >
> > I think people got fooled by Ebola. When the outbreak occurred in West
> > Africa and we had a vaccine pretty much that rolled off shelf within
> weeks,
> > people thought, Ha! That’s easy.
> >
> > But what they didn’t realize is people have been working on an Ebola
> > vaccine for 20 years. They’ve done the animal model testing. They’ve done
> > the testing to make sure that the vaccine was safe and was immunogenic.
> >
> > But that’s not true here. This is a new virus. So we’re starting from
> > scratch.
> >
> > What is it about this virus that makes people confident that a vaccine
> > will be available?
> >
> > I don’t know. You know, I’d say about 15% to 20% of the respiratory
> > infections that we see in our hospital in the winter months are [types
> of]
> > coronavirus. This is a virus that has been around for 50 years.
> >
> > But here are these three newer strains of coronavirus — MERS, SARS, and
> > now this COVID-19. The first two viruses, SARS and MERS, have come and
> gone.
> >
> > I think this [COVID-19] virus likely will come back because it’s
> > different. If you were infected with SARS or MERS viruses, you were sick.
> > And it’s very easy to tell who was sick and who wasn’t. You could then
> > quarantine those people — put a moat around them, if you will — so that
> > they wouldn’t infect others. So those infections quickly died out. This
> > virus is more like flu. It spreads in a similar manner to flu by
> > respiratory droplet. It’s about as contagious as flu. It has the same set
> > of symptoms as flu. And I think in the end, frankly, it’s going to have
> the
> > same mortality rate as flu.
> >
> > There are certainly human studies showing that if you’re infected with a
> > coronavirus — meaning one of the typical coronaviruses — you can have
> > immunity to that strain for at least a year and probably longer. That’s
> > encouraging. If natural infection can protect you, then it’s encouraging
> > that it can produce an immune response which is protective and which you
> > should be able to mimic with vaccination.
> >
> > Vaccine development is tightly regulated. How much of that is about
> safety
> > vs. red tape?
> >
> > If you’re going to be testing this in otherwise healthy people who are
> > very, 

Re: [MBZ] Coronavirus Vaccine

2020-03-13 Thread Meade Dillon via Mercedes
Thanks Gerry, some common sense there.

" There’s a virus that the CDC currently estimated has killed between
20,000 and 45,000 people in the United States -- influenza. But only half
the country gets that vaccine.

There’s only 14 deaths [in the U.S., as of Friday afternoon] from COVID-19,
but everybody would get a vaccine now.

The point being: We’re not very good at assessing risk."

I think we are up to 40 dead now from this Wuhan flu.
-
Max
Charleston SC


On Fri, Mar 13, 2020 at 12:24 PM archer75--- via Mercedes <
mercedes@okiebenz.com> wrote:

>
>
>
> Philly vaccine pioneer: We can’t rush a coronavirus vaccine | Q
>
>
> At a White House news conference Tuesday, Anthony Fauci, the head of the
> National Institute of Allergy and Infectious Disease, told President Donald
> Trump a coronavirus vaccine would likely not be available within the next
> year or two. Trump responded: “I like the sound of a couple of months
> better.”
>
> But a vaccine is not going to be available in the next couple of months,
> and according to Dr. Paul Offit, that’s appropriate. Offit, director of the
> Vaccine Education Center at Children’s Hospital of Philadelphia, is the
> co-developer of the rotavirus vaccine. It took roughly 26 years to perfect
> that protection against a disease that, according to the Centers for
> Disease Control and Prevention, was the leading cause for severe diarrhea
> in children before the vaccine’s introduction in 2006.
>
> Why is it unrealistic to expect a vaccine for coronavirus in a few months?
>
> Nobody’s ever seen this virus before. Therefore, if you’re interested in
> making a vaccine, you first had access to that virus only a couple months
> ago. That’s not long.
>
> [To make a vaccine] you first need to make a decision as to what approach
> you want to take. Then you have to do extensive animal model testing to
> make sure that the approach that you’ve taken is safe in animals, and that
> it induces an immune response which would likely be protective. Then you
> gradually do studies in people to make sure it’s safe, and then to make
> sure that it induces an immune response. That takes time, a lot of time,
> typically years. Then and only then, are you ready to put it into people to
> see whether or not it works in an outbreak situation.
>
> In 2018, after the World Health Organization declared an Ebola outbreak in
> the Democratic Republic of Congo, there was an experimental vaccine very
> quickly.
>
> I think people got fooled by Ebola. When the outbreak occurred in West
> Africa and we had a vaccine pretty much that rolled off shelf within weeks,
> people thought, Ha! That’s easy.
>
> But what they didn’t realize is people have been working on an Ebola
> vaccine for 20 years. They’ve done the animal model testing. They’ve done
> the testing to make sure that the vaccine was safe and was immunogenic.
>
> But that’s not true here. This is a new virus. So we’re starting from
> scratch.
>
> What is it about this virus that makes people confident that a vaccine
> will be available?
>
> I don’t know. You know, I’d say about 15% to 20% of the respiratory
> infections that we see in our hospital in the winter months are [types of]
> coronavirus. This is a virus that has been around for 50 years.
>
> But here are these three newer strains of coronavirus — MERS, SARS, and
> now this COVID-19. The first two viruses, SARS and MERS, have come and gone.
>
> I think this [COVID-19] virus likely will come back because it’s
> different. If you were infected with SARS or MERS viruses, you were sick.
> And it’s very easy to tell who was sick and who wasn’t. You could then
> quarantine those people — put a moat around them, if you will — so that
> they wouldn’t infect others. So those infections quickly died out. This
> virus is more like flu. It spreads in a similar manner to flu by
> respiratory droplet. It’s about as contagious as flu. It has the same set
> of symptoms as flu. And I think in the end, frankly, it’s going to have the
> same mortality rate as flu.
>
> There are certainly human studies showing that if you’re infected with a
> coronavirus — meaning one of the typical coronaviruses — you can have
> immunity to that strain for at least a year and probably longer. That’s
> encouraging. If natural infection can protect you, then it’s encouraging
> that it can produce an immune response which is protective and which you
> should be able to mimic with vaccination.
>
> Vaccine development is tightly regulated. How much of that is about safety
> vs. red tape?
>
> If you’re going to be testing this in otherwise healthy people who are
> very, very unlikely to die from this infection, you better make sure it’s
> safe. So you want those regulations in place.
>
> An example is the dengue vaccine. When it was tested in Latin America and
> Philippines, it was found to actually increase your risk of dengue shock
> syndrome. Children who were less than 9 years of age, who had never been
>