We report 5 cases of chronic myelogenous leukemia (CML) and 1 case of acute myeloid leukemia (AML) with the dual presence of t(9;22) and inv(16). --Posted by Rob to
CML Newswire: Medical And Technical News On Chronic Myelogenous Leukemia at 2/17/2006 11:55:41 PM
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Imatinib mesylate (STI571), a specific inhibitor of BCR/ABL tyrosine kinase, exhibits potent antileukemic effects in the treatment of chronic myelogenous leukemia (CML). --
Posted by Rob to CML Newswire: Medical And Technical News On Chronic Myelogenous Leukemia
at 2/17/2006 11:35:38 PM
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Since its introduction 6 years ago, imatinib mesylate, a selective tyrosine kinase inhibitor, has been a phenomenon in treating chronic myelogenous leukemia (CML) with remarkably superior cytogenetic and molecular response rates at all stages of CML followed by longer progression free survival.
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The hitherto unknown 2-methylsulfanyldecanoic acid and 2-methylsulfanyldodecanoic acid were synthesized from methyl decanoate and methyl dodecanoate, respectively, through the reaction of lithium diisopropylamide and dimethyldisulfide in THF followed by saponification with potassium hydroxide in et
OBJECTIVE: To report disease transformation in 3 imatinib mesylate treated Philadelphia chromosome-positive chronic myelogenous leukemia (Ph(+)CML) patients who achieved cytogenetic response.--
Posted by Rob to CML Newswire: Medical And Technical News On Chronic Myelogenous Leukemia
at 2/17/2006
The virtually obligatory presence of the Philadelphia chromosome may suggest a causal homogeneity, but chronic myelogenous leukemia (CML) is a clinically heterogeneous disease. This may be a consequence of the variable BCR breakpoints on chromosome 22 and of nonrandom secondary chromosomal abnormal
PURPOSE: Chronic myelogenous leukemia (CML) is a disease characterized cytogenetically by the presence of the Philadelphia chromosome. Recent studies suggested that altered PDCD5 _expression_ may have significant implications in CML progression.
--Posted by Rob to
CML Newswire: Medical And Techni
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With me it is not shortness of breath issue and has nothing to do with
lungs or the bronchial system. My problem is restricted airflow
through the nasal passages, a condition that hits a lot of people,
especially men, in their 60s and 70s. The reason I suspect Gleevec
might have something to do
Hi Mike, I have had nighttime breathing problems related to reflux, which has nothing to do with the fact that I am on Gleevec. I even woke up gasping for breath once - not fun. A visit to a gastroenterologist fixed me right up (Nexium, yay!). Just thought I'd throw that in - good luck finding
You might want to check your hemogloben count from your last blood
test.
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