Dear Freesurfer experts,
We investigated the relation between cortical thickness and performance on
several cognitive tasks within a large group of Parkinson’s disease patients,
but are slightly puzzled by the results. We obtained several, both in the
vertex-wise analysis in qdec and in the
Hi Stan
we have found positive correlations between performance (in this case
CVLT) and thickness, so it is certainly possible. And negative correlations
aren't necssarily false - you could certainly imagine that successful
pruning for example could help performance. Have you visually inspecte
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From: Bruce Fischl [fis...@nmr.mgh.harvard.edu]
Sent: 05 February 2013 15:54
To: Berg, S.F. van den
Cc: Freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Difficult results from our PD data
Hi Stan
we have found positive correlations between performance (in this case
CVLT) and thickness
Hi Stan, the VBM results may be picking up changes in GM volume. These
volume changes may be driven by differences in surface area and would
not necessarily show up in a thickness analysis. Maybe the surface area
is increasing with performance but the thickness is decreasing. You can
do a surfa
