Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-11-02 Thread Lars M. Rimol
Hi Martin, Does that mean that one would expect to see reduced lgi (local gyrification index) where this occurs? Thank you! LMR yours, Lars M. Rimol, PhD Norwegian University of Science and Technology (NTNU) Trondheim, Norway On Wed, Oct 29, 2014 at 3:39 PM, Martin Reuter wrote: > Hi Lars

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-10-29 Thread Martin Reuter
Hi Lars, two thoughts that came up reading this thread: - each vertex has usually more than 3 triangles (your first mail), the number differs depending on where you are. With a uniform mesh you'd have nearly 60 degree angles so you'd have approx 6 triangles at a vertex. - wm volume can increase

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-10-29 Thread Bruce Fischl
Hi Lars yes, it seems plausible, particularly since it is so universal. cheers Bruce On Wed, 29 Oct 2014, Lars M. Rimol wrote: Hi Bruce (and Jorge), Yes, it's the wm surface.  I have also done the analyses with the pial surface and the results are similar to wm surface. To your second que

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-10-29 Thread Lars M. Rimol
Hi Bruce (and Jorge), Yes, it's the wm surface. I have also done the analyses with the pial surface and the results are similar to wm surface. To your second question: White matter volume increased over this time period (lme analysis; controls: logP = 8.49, patients: logP = 6.34). Since the co

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-10-28 Thread Lars M. Rimol
Hi Doug, For some reason, I no longer get an e-mail when you respond to my questions on the mailinglist, so until today I only saw the first response to this question (from Bruce). Anyway, I get your point about smoothing and clusters but I guess showing a continuous cortical map with vertex valu

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-09-09 Thread Douglas N Greve
This is tough to interpret, but basically, yes it would be 0-.004mm2/year. It is not quite right to say that it is at that vertex because of smoothing, but in that area. It is also hard to say what the total change would be for a cluster. One could sum the changes over the cluster vertices, bu

Re: [Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-09-06 Thread Bruce Fischl
Hi Lars which surface are you using? If it's the white surface you might try looking at white matter volume to see if it is decreasing cheers Bruce On Sat, 6 Sep 2014, Lars M. Rimol wrote: Hi, I have performed a longitudinal analysis using the lme module in FreeSurfer, with this model: 

[Freesurfer] how to interpret a change in area of 0.004 mm² per year?

2014-09-06 Thread Lars M. Rimol
Hi, I have performed a longitudinal analysis using the lme module in FreeSurfer, with this model: *intercept(random effect) + centered age + group + group x centered age + sex* I tested the effect of time with this contrast vector [ 0 1 0 0 0 ]. Dependent variable is area. Here, mapping the se