Re: Notes from informal Demo F2F / "aha"

2007-03-07 Thread Mark Montgomery
Thanks Alan for the explanation- helps those of us not engaged in the phone conferences to understand, which is of course necessary in order to add value. value of component research? (not sure what you mean) Making an argument for more research investment in this particular area. Some foo

Re: Notes from informal Demo F2F

2007-03-07 Thread William Bug
One final note, since my last few emails may have clouded this issue: 1) However much I may believe we are closer than it may seem - despite the very real concerns Nigam points out below - to providing a means whereby domain expert scientists will be able to construct the manner of stateme

RE: Notes from informal Demo F2F

2007-03-06 Thread Nigam Shah
Hi Alan, Tim and Steve (the other HyBrow guy) have discussed this in some detail I believe. Its great to have formally structured representations at the level of biological entities created by the scientists themselves. However, right now (A) The ontologies and relations for doing so might or mig

RE: Notes from informal Demo F2F

2007-03-06 Thread Eric Neumann
ilto:[EMAIL PROTECTED] Sent: Tue 3/6/2007 7:33 PM To: William Bug Cc: Eric Neumann; Alan Ruttenberg; public-semweb-lifesci@w3.org Subject: Re: Notes from informal Demo F2F Bill, I am trying to understand your proposal. Which are you suggesting: (1) we curate in to SWAN some existing published

Re: Notes from informal Demo F2F

2007-03-06 Thread William Bug
Sorry to contribute to what appears to be an endless chain, here, but - I see the relation between this OBO Phenotype Assertion Wiki page and SWAN EXACTLY as Tim describes it below. Also - I would not expect working neuroscientists to go through what I did to produce what's on that page - H

Re: Notes from informal Demo F2F

2007-03-06 Thread William Bug
Many thanks, Alan. I think you do an excellent job capturing most of the essential issues related to the effort depicted on that page - with two caveats: 1) I'm not asking or expecting the SWAN group to change anything about what they are doing internally in SWAN. I'm only suggesting th

Re: Notes from informal Demo F2F

2007-03-06 Thread kc28
Hi Eric, I was the ?. I attended for about 1.5 hours of the call and then I had to leave quietly (I didn't want to disturb the discussion) for teaching a class. I think the suggestions are great. It's important to show the benefits that SW can potentially bring to the healthcare and life sci

Re: Notes from informal Demo F2F / "aha"

2007-03-06 Thread Alan Ruttenberg
On Mar 6, 2007, at 5:19 PM, Mark Montgomery wrote: I agree with Olivier, particularly when considering multi-component systems (certainly our goal). Which brings up the questions of priorities? (1-10 each?) Is it to demonstrate the functionality and value of languages/OWL? informatics? un

Re: Notes from informal Demo F2F

2007-03-06 Thread Tim Clark
Alan, Thanks for that summary. SWAN is not a software project - it is a project for a technology- mediated social infrastructure. Those fancy words mean we are trying to get the working scientists themselves to curate the material for their own benefit, self-understanding & "karma points".

Re: Notes from informal Demo F2F

2007-03-06 Thread Alan Ruttenberg
Here's my analysis: I think Bill wants (1). Bill is trying to convince the SWAN team to curate to a level deeper than you are going now, by naming and collecting relationships between the biological entities that are being talked about in the paper SWAN curates. The page he references is

Re: Notes from informal Demo F2F

2007-03-06 Thread Tim Clark
BIll: (1) or (2) or none of the above is good enough for right now. I am finding your proposal difficult to follow. Tim On TuesdayMar 6, 2007, at 7:43 PM, William Bug wrote: Sorry, Tim. Can't really go into more detail right now. I have a lot of planning still to do on an all day meet

Re: Notes from informal Demo F2F

2007-03-06 Thread William Bug
Sorry, Tim. Can't really go into more detail right now. I have a lot of planning still to do on an all day meeting I must lead tomorrow. I lay it out considerable detail on this proposal on that page I cite below: http://esw.w3.org/topic/HCLS/OntologyTaskForce/ OboPhenotypeSynta

Re: Notes from informal Demo F2F

2007-03-06 Thread William Bug
Meant to add I don't mean to imply the implicated models of cellular physiology (LTP/LTD) and of disease - or the hypotheses are not equally important. I just feel there will be a "missing link" between those high level, abstracted views and the large data repositories (GENEBANK sequences,

Re: Notes from informal Demo F2F

2007-03-06 Thread Tim Clark
Bill, I am trying to understand your proposal. Which are you suggesting: (1) we curate in to SWAN some existing published work hypothesizing connection of, for example, MPTP/MPP+ mechanism to some forms of PD; or (2) we build "our own" hypothesis of MPTP/MPP+ mechanism relationship etc, not

Re: Notes from informal Demo F2F

2007-03-06 Thread William Bug
Hi All, Looks like a lot of substantive work was done at the F2F. Kudos to all who participated! I'd like to highlight one of the issues EricN mentioned. On Mar 6, 2007, at 8:29 AM, Eric Neumann wrote: As part of the scernario using the known aggregate of facts, add a few *select* hypothe

Re: Notes from informal Demo F2F / "aha"

2007-03-06 Thread Mark Montgomery
Eric Neumann" <[EMAIL PROTECTED]> Cc: "Alan Ruttenberg" <[EMAIL PROTECTED]>; Sent: Tuesday, March 06, 2007 10:19 AM Subject: Re: Notes from informal Demo F2F / "aha" Eric Neumann wrote: [...] It was also apparent that we need to identify what the specific &quo

Re: Notes from informal Demo F2F

2007-03-06 Thread Twigger Simon
Dear All, I've been lurking on list for a while and saw this email and wanted to chime in briefly. I have a few other suggestions for some of your 'Other Resources' that we have at the Rat Genome Database. We have rat genes annotated with the Mammalian Phenotype ontology, along with a di

RE: Notes from informal Demo F2F

2007-03-06 Thread Eric Neumann
At one point during the informal F2F, the folks on the call (Karen Skinner, Eric P, John Barkely, Scott Marshall, Eric N, ?) were cut off from the conference, but we ended up having a discussion amonst ourselves, where we came up with a few suggestions regarding the demo: - it might be compell

Re: Notes from informal Demo F2F

2007-03-06 Thread Alan Ruttenberg
Lovely! We would indeed data rather than web pages in order to translate into RDF/OWL and integrate into our queries. I'll contact you off-list to talk about possibilities. -Alan On Mar 6, 2007, at 9:42 AM, Twigger Simon wrote: Dear All, I've been lurking on list for a while and saw this e