We see approximately 20% of our pts with severe sepsis being treated on 
general medsurg floors. these are typically patients with a single organ 
dysfunction (typically lactate 2-4 or a small Cr. elevation) who have 
rather rapid improvement in vital signs after fluids in the ED.

We see that approximately 15% of these patients end up requiring transfer 
to step down (more common) or ICU (less common) in the 48 hours after 
admission. The patients that do transfer have a mortality rate similar or 
slightly higher than patients initially admitted to a step down unit or 
ICU. We have to date been unable to determine which characteristics 
predict which patients will further deteriorate.

Based on these observations we are trying to guarantee that such patients 
are admitted directly to at least a step down unit. We struggle with this 
because of space limitations, so this is an ongoing issue we are working 
on.

Joe
Joseph Clement RN, MS, CCNS
Clinical Nurse Specialist

San Francisco General Hospital
phone: (415) 206-6174
pager: (415) 327-0220
[email protected]




"Townsend, Sean, M.D." <[email protected]> 
Sent by: [email protected]
03/17/2013 09:37 AM

To
"'Doberenz, Doris'" <[email protected]>, 
"'[email protected]'" 
<'[email protected]'>
cc

Subject
Re: [Sepsis Groups] Where Does Severe Sepsis Belong?






Dear Doris,

Questions about strategies to improve practice on the listserv are a good 
thing. Not having a strategy beyond everyone's best judgment is probably 
not the right answer on the exam. 

I'm sure you have great judgment, but we all know many colleagues who 
would benefit from some guidance on where to place patients. 

Judgment alone hasn't done much to get adherence to best therapies. In the 
world's best example, Intermountain Healthcare in Utah, adherence to 
bundled therapies is 85% or so. Their mortality rate for severe sepsis is 
less than 10%. The rest of us can't say either of those things. Their 
publication is in peer review and soon we'll all see clearly the power of 
their example.

I just wanted to survey the crowd that has demonstrated interest in this 
subject for what they do so I can fix my own problems.

Sean




Sean R. Townsend, M.D.
Vice President of Quality & Safety
California Pacific Medical Center
2330 Clay Street, #301
San Francisco, CA 94115
email [email protected]
office (415) 600-5770
fax (415) 600-1541

-----Original Message-----
From: Doberenz, Doris [[email protected]]
Sent: Sunday, March 17, 2013 08:44 AM Pacific Standard Time
To: '[email protected]'
Subject: Re: [Sepsis Groups] Where Does Severe Sepsis Belong?

Why is so much written about this without much real content? How many more 
or less rhetoric questions with or without answers because our patients 
and their diseases and severity actually vary... OOOPS who'd have thought 
that!? For example 'where severe sepsis belongs' will depend on seeing the 
patient as a clinician in addition to certain quite clear severity 
criteria in their context and conjunction e.g. heart rate, blood pressure, 
resp rate, urine output, lab signs of organ failure, lactate, central 
venous sats if available), and to decide how severe the whole situation is 
and thus how much monitoring and support a specific patient in a specific 
situation and severity needs. How many more mails and how many more pages 
of guidelines and time and expense of development of these guidelines by 
experts do we need for this and how many not always sufficiently evidence 
based but dictatorial bundles, which then get overtaken by the scientific 
evidence (e.g APC, steroids)??? Back t
 o the shopfloor (and the floor or the ICU according to the real need) and 
back to basics, and back to applying good medicine and good science for 
each individual patient and his or her specific situation rather than 
being spoonfed and dictated bundle criteria from some "institute" without 
sufficient robust and durable scientific evidence...


Doris Doberenz FRCA FFICM EDAIC EDA
Consultant
Intensive Care Unit and Anaesthetic Department
Charing Cross Hospital
Fulham Palace Rd
London W6 8RF
Tel 020 3311 1234 bleep 5742
Mobile 07855 754 160









-----Original Message-----
From: [email protected] [
mailto:[email protected]] On Behalf Of Townsend, 
Sean, M.D.
Sent: 15 March 2013 06:32
To: '[email protected]'
Subject: [Sepsis Groups] Where Does Severe Sepsis Belong?

It's been a long time since I've had to ask this question. I used to think 
I knew the answer.

Here it is: do all patients who meet severe sepsis criteria need to be 
admitted to the ICU ?

Examples:

1. Pneumonia, fever, tachycardia, INR 1.5.
2. Cellulitis, leukocytosis, fever, creatinine 2.0.
3. UTI, leukocytosis, fever, lactate 3.0.

Where do people put these patients in reality? What mind of monitoring do 
they deserve?

By prevailing bundles, each gets lactate checked, blood cultures, broad 
spectrum antibiotics. That's it. Good enough? Good enough for the floor? 
Need the ICU? Why?

Sean


Sean R. Townsend, M.D.
Vice President of Quality & Safety
California Pacific Medical Center
2330 Clay Street, #301
San Francisco, CA 94115
email [email protected]
office (415) 600-5770
fax (415) 600-1541
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