Terri, Everyone is different due to bodyweight so I am told. I know Marsha took 3 mouthfuls a day and that helped her. Right now I am trying to get my body balanced with acidophillus to see what is from that and what is left of the lyme. I did take it three times a day and was up to an ounce or so at a time, maybe more, but that was the low (5-6)ppm. I am taking 500ppm and am taking a tsp at a time. If you are feeling good just try to increase every two weeks until the symptoms are gone and then continue on for a couple of months just to be sure. If I left anything out let me know, it is late and this has been a day from h--- Donna
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