In analyzing Dave's data and reviewing again the Altman study I believe that I have found (or more accurately, stumbled upon) the reason why EIS is safer to use than other forms of silver. It also explains why EIS is both processed the same as other silver compounds, primarily by the liver, and also differently at the same time. I will go into that shortly. I think you will find it interesting. Either as a long sought after answer or as an opportunity to tell me what an idiot I am.
But first, a request. I think that some good information can be gained from evaluating the silver usage of those on the list who have blue moons in their fingernails. I would like to request all who can, to provide it the following info: Average daily amount used. Average ppm of EIS How EIS was made Number of years till nail beds turned blue/grey Any unusual supplements used in conjunction with the EIS The more data we have the better we can know how to best use EIS. While I think that there are few things we can conclusively draw from Dave's experience, one item think I feel is encouraging is that there appears to be a significant difference between the time blue moons appear and when argyria might occur. And maybe we can use Dave's timeline as a rough predictor for someone with blue moons to develop more serious signs with or without changes in usage. And yes, it would be very speculative but it might be better that what we have now - nothing. For those who might wish to brush up on the Roger Altman Silver Elimination Study, here is a link to Roger's report. http://www.silver-colloids.com/Papers/AltmanStudy.PDF And here is a discussion of the study and silver elimination in general: http://www.info-archive.com/colsil%20silvertox.ht First, I would like to discuss how much silver the liver can the liver excrete in a day. When silver compounds in the blood exceed that limit it leads to increased deposition of silver in the tissues. The excess silver has to go somewhere. The following study puts that at about 1 mg of silver per day (or 3.4 oz of 10 ppm CS): "In a study involving biologic monitoring of workers (n = 37) in one of the silver smelting and refining industries in which the exposure is entirely by inhalation, silver was found in the blood (0.011 :g per milliliter [mL]), urine (<0.005 :g/mL), and feces (15 :g/g). Control subjects excreted about 1.5 :g/g in the feces (n = 35). The author suggests that human fecal excretion of silver at exposure levels equal to the Threshold Limit Value (TLV) (0.1 mg per cubic meter [m3]) would be about 1 mg of silver per day (Di- Vincenzo et al. 1985)." If you exceed this limit continuously over a period of time you will have excess silver deposited in the tissues. For non EIS silver compounds, it has been found that roughly 10% of the silver ingested is absorbed into the bloodstream. That would indicate that you can take up to 34 oz of 10 ppm CS per day and not saturate the biliary excretion path. However, the Altman study shows that 100% of ingested EIS enters the bloodstream and so EIS should be limited to 3.4 oz of 10 ppm EIS, or equivalent, to remain within the bilary excretion capability of the liver. However, should you exceed that amount, EIS is uniquely processed by the body and that is where EIS becomes safer to use and less likely to cause argyria. To understand what happens when you take more EIS than the liver bilary excretion path can handle, you need to look at the Altman study. The Altman study starts by Roger Altman taking 2.34 mg of silver, in the form of EIS, daily for an extended period of time. That amount is significantly higher than the 1 mg daily amount the liver can process and caused a buildup of silver in Roger's system. Roger then stopped taking any EIS and then measured over a 96 day period the excretion of silver out through the liver (feces) and the kidney (urine). Over the 96 day period, the silver excreted through the feces was fairly constant but varying around 1.5 mg per day. I believe that this represents the excretion capacity of Roger's bilary excretion path and is consistent with the study referenced previously. What is interesting, and what sets EIS apart from other forms of silver, is what was happening in the kidney. For silver compounds other than EIS, only a little silver is excreted through the urine. Even when there is excess silver in bloodstream or when the bilary excretion path is blocked and preventing the liver from excreting silver. But the Altman study shows a large amount of silver excreting out in the urine. Usually in the 3 to 4 mg per day range, but at times as much as 10 mg. It is this result that has erroneously led people to believe that EIS is primarily excreted through the urine. Out at the 96th day samples, the silver in the urine has dropped to 0.64 mg but the excretion through the feces was 2 mg, indicating that the bilary excretion path was still eliminating silver at its maximum capacity while only a little silver was still passing out through the kidney. I propose that the primary excretion path for EIS is through the liver EXCEPT when the amount of silver from EIS in the blood exceeds the liver's capacity to excrete it AND AS LONG AS THE SILVER IS IN SOLUTION. Why do I say that? It is clear that EIS is somehow unique from other types of silver. We can tell that by the fact that it is processed differently as shown by the study. But what is that difference? I propose that it is that EIS forms silver chloride in the stomach acid. And that silver chloride has a low solubility in the blood. I also propose that silver chloride does not have to go into solution to pass into the bloodstream. But that the silver chloride molecule is small enough to pass into the blood while still a particle. Small particles in the blood are filtered by the kidneys. When the silver chloride exceeds the solubility capability of the blood, it exists in the blood as particles and is filtered out by the kidney. It is this unique excretion path that makes EIS less likely to cause argyria. However, EIS is not impervious to causing argyria. As long as silver content in the blood is higher than what the liver can process, some of that silver is being deposited in the tissues. It is just that EIS significantly reduces the problem. It also makes me think that the problems with using non distilled water and additives to the water is not caused so much by the silver chloride that is formed but by other silver compounds formed with other impurities. - Steve N -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: silver-list@eskimo.com Address Off-Topic messages to: silver-off-topic-l...@eskimo.com The Silver List and Off Topic List archives are currently down... List maintainer: Mike Devour <mdev...@eskimo.com>
