This might be a wild goose chase, and I'm not convinced it's directly
related, but AMD multi-core CPUs are known to have timing issues.  Google
for "AMD negative ping" and you'll see it affects the results from the ping
utility for example.  They've released a "Dual-Core Optimizer" patch to
correct this:
http://www.amd.com/us-en/Processors/TechnicalResources/0,,30_182_871_13118,0
0.html

This is backwards from your situation, but it at least demonstrates issues
in a related area, so perhaps there's something there.

Doug




> -----Original Message-----
> From: [EMAIL PROTECTED] [mailto:sqlite-users-
> [EMAIL PROTECTED] On Behalf Of Benilton Carvalho
> Sent: Monday, September 08, 2008 2:20 PM
> To: [email protected]
> Subject: [sqlite] SQLite vs. quad-cores
> 
> Hi everyone,
> 
> I'm a BioConductor developer and we use SQLite (via RSQLite package) to
> handle annotation of high-density oligonucleotide microarrays.
> 
> Our solution, implemented in the pdInfoBuilder package, worked great
> until
> we got machines with quad-core processors. One particular setup is a
> machine
> with 2 Quad-Core AMD Opteron Processor 2356. The processes that usually
> took
> 1-2 hours on older machines (dual-cores AMD), now take 6-8 hours on the
> new
> computers.
> 
> We thought there would be something wrong with our switch (given the
> particular network scenario we have here), and changing it didn't solve
> the
> problem. Later, we decided to run everything on local storage (instead
> of
> network), and the same behavior was observed again.
> 
> Is there anything else that you guys could recommend?
> 
> thanks a bunch,
> 
> benilton
> _______________________________________________
> sqlite-users mailing list
> [email protected]
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