Has anyone tried out the the MSBL Email Blocklist (EBL) HashBL.pm with Spamassassin from msbl.org and possibly considered packaging this module (available from this page: http://msbl.org/ebl-implementation.html) with SpamAssassin (perhaps in a forthcoming release)? rSpamD already has internal support for the EBL. So I believe the MSBL folks are for this sort of thing in general.
This plugin looks through the message (not just headers) for email addresses which have been identified as email drop boxes for scams like 419 advance fee fraud. It then looks hashes of these addresses up in a blocklist. I'm not affiliated with these folks. I do however use this module in my setup though and find it catches a bunch of things we wouldn't have otherwise caught. Michael Grant