This subclinical scenario presents the uncomfortable strategy of allowing for voluntary (pre)infection of some kind. ... somewhat reminiscent of an early approach to fighting polio.
Jim Dickenson wrote: A discussion that I saw talked about how the size of the virus load (the inoculum) may affect disease progression... a few virions from touching a handrail may lead to a longer and milder buildup to symptoms (if any) than receiving a huge load of virions...the severity of some of these outbreaks may be a direct function of how efficiently the infected (both symptomatic and asymptomatic) infected the never infected.
